Results 51 to 60 of about 60,752 (282)

Recombinant SARS-CoV-2 Delta/Omicron BA.5 emerging in an immunocompromised long-term infected COVID-19 patient

Scientific Reports
The emergence of the SARS-CoV-2 virus led to a global pandemic, prompting extensive research efforts to understand its molecular biology, transmission dynamics, and pathogenesis.
Ignacio Garcia, Jon Bråte, Even Fossum, Andreas Rohringer, Line V. Moen, Olav Hungnes, Olav Fjære, Kyriakos Zaragkoulias, Karoline Bragstad   +8 more
doaj   +1 more source

Detection of novel coronaviruses in bats in Myanmar.

PLoS ONE, 2020
The recent emergence of bat-borne zoonotic viruses warrants vigilant surveillance in their natural hosts. Of particular concern is the family of coronaviruses, which includes the causative agents of severe acute respiratory syndrome (SARS), Middle East ...
Marc T Valitutto, Ohnmar Aung, Kyaw Yan Naing Tun, Megan E Vodzak, Dawn Zimmerman, Jennifer H Yu, Ye Tun Win, Min Thein Maw, Wai Zin Thein, Htay Htay Win, Jasjeet Dhanota, Victoria Ontiveros, Brett Smith, Alexandre Tremeau-Brevard, Tracey Goldstein, Christine K Johnson, Suzan Murray, Jonna Mazet   +17 more
doaj   +1 more source

Rotavirus A in Brazil: Molecular Epidemiology and Surveillance during 2018–2019

, 2020
Rotavirus A (RVA) vaccines succeeded in lowering the burden of acute gastroenteritis (AGE) worldwide, especially preventing severe disease and mortality.
Rosane Maria Santos de Assis, José Paulo Gagliardi Leite, Juliana da Silva Ribeiro de Andrade, Fábio Correia Malta, Adriana Gonçalves Maranhão, Tulio Machado Fumian, Meylin Bautista Gutierrez, Alexandre Madi Fialho, Sérgio da Silva e Mouta, Marize Pereira Miagostovich   +9 more
core   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

A century of emergence: trends and patterns in human viral pathogens, 1900–2024, a systematic review

BMC Infectious Diseases
Background Emerging infectious diseases (EIDs) pose ongoing global health threats, making it essential to understand their temporal, geographic, and biological patterns to inform prevention and control strategies. Methods We conducted a systematic review
Ashley Quigley, Rosalie Chen, Adriana Notaras, Atalay Goshu Muluneh, Samsung Lim, Abrar A. Chughtai, C. Raina MacIntyre   +6 more
doaj   +1 more source

Human-Altered Landscapes and Climate to Predict Human Infectious Disease Hotspots

Tropical Medicine and Infectious Disease, 2022
Background: Zoonotic diseases account for more than 70% of emerging infectious diseases (EIDs). Due to their increasing incidence and impact on global health and the economy, the emergence of zoonoses is a major public health challenge.
Soushieta Jagadesh, Marine Combe, Rodolphe Elie Gozlan   +2 more
doaj   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Estudio epidemiológico de los brotes de gastroenteritis aguda de etología vírica en Cataluña

, 2008
[spa] La gastroenteritis aguda es un problema de salud, constituyendo la primera causa de morbilidad y de mortalidad en la población infantil en los países en vías de desarrollo.
Torner Gràcia, Núria
core   +6 more sources

Risks and Challenges of Arboviral Diseases in Sudan: The Urgent Need for Actions

Viruses, 2020
The risk of emergence and/or re-emergence of arthropod-borne viral (arboviral) infections is rapidly growing worldwide, particularly in Africa.
Ayman Ahmed, Isabelle Dietrich, A. Desiree LaBeaud, Steve W. Lindsay, Ahmed Musa, Scott C. Weaver   +5 more
doaj   +1 more source

Serology for trachoma surveillance after cessation of mass drug administration. [PDF]

, 2015
BACKGROUND: Trachoma, caused by Chlamydia trachomatis (Ct), is the leading infectious cause of blindness worldwide. Yearly azithromycin mass drug administration (MDA) plays a central role in efforts to eliminate blinding trachoma as a public health ...
William Makupa, Anthony W Solomon, Lammie, Patrick J, Martin J Holland, Diana L. Martin (300642), Anthony W. Solomon (146301), Chris Drakeley (79962), Martin, Diana L, Diana L Martin, Molina, Sandra, Patrick J Lammie, Drakeley, Chris, David C. W. Mabey (168760), Makupa, William, Frank Sandi, Chris Drakeley, Augustin Lasway (695785), Bid, Rhiannon, Rhiannon Bid, Sandra Molina, David C W Mabey, Massae, Patrick A, Rhiannon Bid (695782), Sandra Molina (211312), Augustin Lasway, Philippin, Heiko, Solomon, Anthony W, Patrick J. Lammie (113203), Goodhew, E Brook, E Brook Goodhew, Heiko Philippin (695786), Martin J. Holland (146345), Holland, Martin J, Patrick A Massae, Lasway, Augustin, E. Brook Goodhew (300641), Sandi, Frank, Patrick A. Massae (695784), Mabey, David CW, Heiko Philippin, Frank Sandi (695783), William Makupa (695787)   +41 more
core   +1 more source