Results 71 to 80 of about 60,752 (282)

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito, Kamal Benguerba, Ken Tsuchida, Kazushige Yazawa, Isao Tsumiyama, Hiromitsu Kayama, Sandra P. Reyna, Farid Khan, Richard S. Finkel   +8 more
wiley   +1 more source

Managing Japanese Encephalitis Virus as a Veterinary Infectious Disease Through Animal Surveillance and One Health Control Strategies

Life
Japanese encephalitis virus (JEV) is a mosquito-borne zoonotic flavivirus that circulates primarily within animal populations and occasionally spills over to humans, causing severe neurological disease. While humans are terminal hosts, veterinary species
Jae-Yeon Park, Hye-Mi Lee
doaj   +1 more source

Inebilizumab in AQP4‐Seropositive NMOSD: One‐Year Follow‐Up From a Multicenter, Real‐World Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Real‐world evidence on inebilizumab among neuromyelitis optica spectrum disorder (NMOSD) patients is lacking. This study assessed inebilizumab among Chinese patients with aquaporin 4 autoantibody (AQP4‐IgG)‐seropositive NMOSD in a real‐world setting.
Mengcui Gui, Jiayang Zhan, Wei Li, Tao Jin, Dan He, Daishi Tian, Zhijun Li, Jing Lin, Yue Li, Hongyu Zhou, Bitao Bu   +10 more
wiley   +1 more source

The Development of Rheumatoid Arthritis–Specific Ambulatory Care–Sensitive Conditions: Results of a Consensus Process

Arthritis Care &Research, EarlyView.
Objective Ambulatory care–sensitive conditions (ACSCs) serve as indicators of access, quality, and performance of the health system. This study aimed to determine rheumatoid arthritis (RA)‐specific ACSCs for use in the evaluation of care system access and quality.
Kara Irwin, Candace H. Feldman, Claire E. H. Barber, Gabriel Fabreau, Jake Jennings, Scott Patten, Cheryl Barnabe, Inflammatory Arthritis‐Specific ACSC Consensus Process Working Group   +7 more
wiley   +1 more source

Viral Metagenomic Next-Generation Sequencing for One Health Discovery and Surveillance of (Re)Emerging Viruses: A Deep Review

International Journal of Molecular Sciences
Viral metagenomic next-generation sequencing (vmNGS) has transformed our capacity for the untargeted detection and characterisation of (re)emerging zoonotic viruses, surpassing the limitations of traditional targeted diagnostics. In this review, we critically evaluate the current landscape of vmNGS, highlighting its integration within the One Health ...
Tristan Russell, Elisa Formiconi, Mícheál Casey, Maíre McElroy, Patrick W. G. Mallon, Virginie W. Gautier   +5 more
openaire   +2 more sources

Treating and Preventing Influenza in Aged Care Facilities: A Cluster Randomised Controlled Trial [PDF]

, 2012
PMCID: PMC3474842This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
Dominic E Dwyer, Lindley, RI, Clayton K Chiu, Zhanhai Gao (126426), MacIntyre, CR, Alexander E. Rosewell (126422), Dominic E. Dwyer (126405), Jiehui K Yin, Clayton K. Chiu (126418), C. Raina MacIntyre (126428), Timothy Dobbins, Jiehui K. Yin (126408), Timothy Dobbins (126424), Dwyer, DE, Cameron R M Moffatt, Alexander E Rosewell, Philp, DJ, Zhanhai Gao, Anna S. Dean (113917), Richard I. Lindley (126404), Gao, Z, Chiu, CK, Robert Booy (126402), David J. Philp (23192), Robert Booy, Yin, JK, Heron, LG, Leon G Heron, C Raina MacIntyre, Dobbins, T, Richard I Lindley, Rosewell, AE, Cameron R. M. Moffatt (126415), Moffatt, CRM, Dean, AS, David J Philp, Anna S Dean, Leon G. Heron (126411), Booy, R   +38 more
core   +2 more sources

Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration

Advanced Healthcare Materials, EarlyView.
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu, Lorenzo Moroni, Nicolas Lebonvallet, Vincent Flacher, Paul Wieringa   +4 more
wiley   +1 more source

The role of viruses in human infectious pathology

Вопросы вирусологии
The global virome (virosphere; unformal domain Viraea) has evolved over at least three billion years through continuous co-evolution with the major domains of life, including Archaea, Bacteria, and Eukarya.
Dmitry K. Lvov, Vasily G. Akimkin, Victor V. Maleev, Andrey V. Letarov, Sergey V. Alkhovsky   +4 more
doaj   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

African swine fever in the era of global expansion: Epidemiology, transmission dynamics, viral evolution, and One Health control strategies [PDF]

Veterinary World
Background and Aim: African swine fever (ASF) has become one of the most devastating transboundary diseases affecting domestic pigs and wild boar, causing severe economic losses, disruption of international trade, and threatening global food security ...
Jia Bie
doaj   +1 more source