Conserved Eukaryotic Fusogens Can Fuse Viral Envelopes to Cells [PDF]
Science, 2011 A Caenorhabditis elegans cell-surface fusion protein can promote viral fusion with mammalian cells.
Avinoam, Ori +10 more
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Possible immunoenhancement of persistent viremia by feline leukemia virus envelope glycoprotein vaccines in challenge-exposure situations where whole inactivated virus vaccines were protective. [PDF]
, 1986 Kittens immunized with purified native FeLV-gp70 or -gp85 envelope proteins developed ELISA, but not virus neutralizing, antibodies in their serum to both whole FeLV and FeLV-gp70.
Birch, D +3 more
core
Hepatoma cell density promotes claudin-1 and scavenger receptor BI expression and hepatitis C virus internalization. [PDF]
, 2009 Hepatitis C virus (HCV) entry occurs via a pH- and clathrin-dependent endocytic pathway and requires a number of cellular factors, including CD81, the tight-junction proteins claudin 1 (CLDN1) and occludin, and scavenger receptor class B member I (SR-BI).
Balfe, Peter +5 more
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Human Vaccines & Immunotherapeutics, 2021 The third outbreak of coronavirus (CoV) infection (after SARS-CoV and MERS-CoV) caused by a novel CoV (SARS-CoV-2) of the genus Beta-coronavirus has become a global pandemic.
Abdolkarim Sheikhi +1 more
doaj +1 more source
A Single Substitution in gp41 Modulates the Neutralization Profile of SHIV during In Vivo Adaptation
Cell Reports, 2019 Summary: The HIV-1 envelope glycoprotein (Env) maintains a delicate balance between mediating viral entry and escaping antibody neutralization. Adaptation during transmission of neutralization-sensitive Envs with an “open” conformation remains poorly ...
Qian Wang +9 more
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Viral O‐GalNAc peptide epitopes: a novel potential target in viral envelope glycoproteins
Reviews in Medical Virology, 2015 SummaryViral envelope glycoproteins are major targets for antibodies that bind to and inactivate viral particles. The capacity of a viral vaccine to induce virus‐neutralizing antibodies is often used as a marker for vaccine efficacy. Yet the number of known neutralization target epitopes is restricted owing to various viral escape mechanisms. We expand
Olofsson, Sigvard +4 more
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Localization of viral-envelope-glycoprotein-binding sites in fibronectin [PDF]
Biochemical Journal, 1984 Purified viral-envelope glycoproteins from influenza A virus were found to bind to two fragments of the fibronectin molecule. Human plasma fibronectin was digested by leucocyte cathepsin G, and three different fragments, of Mr 30000, 40000 and 12000-140000, with specific binding functions were isolated.
I, Julkunen, T, Vartio, J, Keski-Oja
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Immunogens and Antigen Processing: Report from a Global HIV Vaccine Enterprise Working Group [PDF]
, 2010 The Global HIV Vaccine Enterprise convened a meeting of a Working Group in July 2009 to discuss recent progress in rational design of the components of an HIV vaccine, such as inserts, vectors and adjuvants,and in understanding antigen processing and ...
John Mascola +3 more
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Acta Médica Portuguesa, 2008 Human immunodeficiency virus (HIV) infection of host cells begins with binding of viral envelope (Env) surface (SU) glycoprotein to specific receptors present at plasma cell membrane.
J M Azevedo-Pereira, Q Santos-Costa
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Retrovirology, 2011 Background Over the last several decades it has been noted, using a variety of different methods, that cells infected by a specific gammaretrovirus are resistant to infection by other retroviruses that employ the same receptor; a phenomenon termed ...
Eiden Maribeth V, Liu Meihong
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