Results 231 to 240 of about 146,326 (305)

Updates on intratumoral therapies in melanoma

open access: yesCancer, Volume 132, Issue 13, 1 July 2026.
Abstract Intratumoral therapies provide an opportunity for novel strategies in the management of advanced melanoma. These approaches deliver concentrated doses of therapeutic immune agents directly into individual tumor(s), achieving local tumor control and induction of systemic antitumor immune responses while minimizing the risk of immune‐related ...
Vincent T. Ma   +12 more
wiley   +1 more source

Studies on the roles of viral envelope surface proteins in cell attachment and entry

open access: yes, 2018
The Ebola virus (EBOV) surface glycoprotein (GP) is a trimeric class I viral fusion protein, which plays a key role in viral attachment and entry. The major cell entry mechanism during EBOV infection involves the endosomal pathway, where GP specifically binds to domain C of NPC1 (a cholesterol transporter) in the endosome, and causes fusion between the
openaire   +1 more source

Mycobacterium avium Subsp. paratuberculosis and Human Endogenous Retrovirus in Italian Patients With Inflammatory Bowel Disease (IBD) and Irritable Bowel Syndrome (IBS)

open access: yesImmunology, Volume 178, Issue 3, Page 417-427, July 2026.
Inflammatory bowel disease (IBD), comprising ulcerative colitis (UC) and Crohn's disease (CD), is a recognised gastrointestinal disorder. Mycobacterium avium subspecies paratuberculosis (MAP) is implicated in IBD pathogenesis. Persistent exposure and active infections by MAP may contribute to the unsilencing of human endogenous retroviruses (HERV ...
Stefano Ruberto   +14 more
wiley   +1 more source

In vivo CAR T cell generation using retargeted and functionalized lentiviral vectors with reduced immunogenicity. [PDF]

open access: yesNat Commun
Ibrahim KE   +11 more
europepmc   +1 more source

Gingival and Periodontal Diseases and Conditions in Children and Adolescents: Consensus Report

open access: yesJournal of Clinical Periodontology, Volume 53, Issue 7, Page 1068-1099, July 2026.
ABSTRACT Background The objectives of this Focused Workshop were to update the epidemiology, aetiology, risk factors, diagnosis and management of gingival and periodontal diseases and conditions in children and adolescents, and to explore the applicability of the 2018 Classification in children and adolescents.
Iain Chapple   +30 more
wiley   +1 more source

From EM to AI: Multiscale imaging of the secretory pathway with insights from plant cells

open access: yesJournal of Microscopy, Volume 303, Issue 1, Page 3-20, July 2026.
Abstract The secretory pathway is a central and evolutionarily conserved feature of eukaryotic cells, responsible for protein and lipid trafficking, membrane biogenesis, signalling, and cellular homeostasis. Its complexity, dynamic behaviour, and nanoscale organisation have made it a longstanding target of microscopy‐driven investigation.
Charlotte Pain, Emily Farley
wiley   +1 more source

Conserved histidine residues and the control of tick-borne encephalitis virus maturation. [PDF]

open access: yesJ Gen Virol
Medits-Weiss I   +4 more
europepmc   +1 more source

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