HIV envelope pseudotyped virus- an indispensable tool in HIV research. [PDF]
Vivekanandan S, Sonawane A, Hanna LE.
europepmc +1 more source
Updates on intratumoral therapies in melanoma
Abstract Intratumoral therapies provide an opportunity for novel strategies in the management of advanced melanoma. These approaches deliver concentrated doses of therapeutic immune agents directly into individual tumor(s), achieving local tumor control and induction of systemic antitumor immune responses while minimizing the risk of immune‐related ...
Vincent T. Ma +12 more
wiley +1 more source
Studies on the roles of viral envelope surface proteins in cell attachment and entry
The Ebola virus (EBOV) surface glycoprotein (GP) is a trimeric class I viral fusion protein, which plays a key role in viral attachment and entry. The major cell entry mechanism during EBOV infection involves the endosomal pathway, where GP specifically binds to domain C of NPC1 (a cholesterol transporter) in the endosome, and causes fusion between the
openaire +1 more source
Creation of enveloped viral replica equipped with SARS-CoV2 spike protein
Kazunori, Matsuura, Hiroto, Furukawa
openaire +2 more sources
Inflammatory bowel disease (IBD), comprising ulcerative colitis (UC) and Crohn's disease (CD), is a recognised gastrointestinal disorder. Mycobacterium avium subspecies paratuberculosis (MAP) is implicated in IBD pathogenesis. Persistent exposure and active infections by MAP may contribute to the unsilencing of human endogenous retroviruses (HERV ...
Stefano Ruberto +14 more
wiley +1 more source
In vivo CAR T cell generation using retargeted and functionalized lentiviral vectors with reduced immunogenicity. [PDF]
Ibrahim KE +11 more
europepmc +1 more source
Gingival and Periodontal Diseases and Conditions in Children and Adolescents: Consensus Report
ABSTRACT Background The objectives of this Focused Workshop were to update the epidemiology, aetiology, risk factors, diagnosis and management of gingival and periodontal diseases and conditions in children and adolescents, and to explore the applicability of the 2018 Classification in children and adolescents.
Iain Chapple +30 more
wiley +1 more source
Comparative Molecular Docking and Pharmacokinetic Profiling of Cinnamic Acid and Oleic Acid from <i>Cinnamomum verum</i> as Potential Inhibitors of Dengue Virus Proteins. [PDF]
Habeeb WH +8 more
europepmc +1 more source
From EM to AI: Multiscale imaging of the secretory pathway with insights from plant cells
Abstract The secretory pathway is a central and evolutionarily conserved feature of eukaryotic cells, responsible for protein and lipid trafficking, membrane biogenesis, signalling, and cellular homeostasis. Its complexity, dynamic behaviour, and nanoscale organisation have made it a longstanding target of microscopy‐driven investigation.
Charlotte Pain, Emily Farley
wiley +1 more source
Conserved histidine residues and the control of tick-borne encephalitis virus maturation. [PDF]
Medits-Weiss I +4 more
europepmc +1 more source

