Role of Gram‐Negative Bacterial Infections in Acute‐On‐Chronic Liver Failure
ABSTRACT Acute‐on‐chronic liver failure (ACLF) is a systemic disease characterised by an acute clinical deterioration of pre‐existing liver cirrhosis leading to multiple organ failure due to systemic inflammation. It may be triggered by the translocation of bacteria and bacterial compounds across the gut barrier.
Camilla Cadoli +5 more
wiley +1 more source
Host factors in parainfluenza virus replication: from entry to innate immunity evasion. [PDF]
Lin X +5 more
europepmc +1 more source
ABSTRACT Background and Aims Chronic hepatitis D is the most severe form of viral hepatitis. Despite recommendations for systematic screening of HBsAg‐positive individuals, hepatitis D infection remains underdiagnosed. Standard HDV virological markers are classically assessed in serum or plasma specimens obtained through venous whole blood sampling ...
Rola Matar +10 more
wiley +1 more source
Optimizing In Vivo CAR T-cell Engineering for Cancer Immunotherapy. [PDF]
Wang R, Yu J, Caligiuri MA, Ma S.
europepmc +1 more source
Beyond Starch: Towards a Scalable Potato Platform for Molecular Farming
Re‐engineering potato as a biosafe and host‐optimised platform for plant molecular farming by integrating intrinsic biological traits with targeted engineering strategies. ABSTRACT Thirty‐five years after the first recombinant protein was produced in potato and 30 years after clinical trials of edible vaccines from its tubers, the crop is being ...
Izabela Anna Chincinska +2 more
wiley +1 more source
Research advances in chikungunya virus: Epidemiology, pathogenesis, and control. [PDF]
Dai S, Li H, Li S, Shao X, Cheng X.
europepmc +1 more source
ABSTRACT HLA loci have been implicated in several diseases, including HIV‐1, from different world populations. It is necessary to characterise HLA allele variation at the population level prior to investigating associations linked to human diseases. In global databases, limited high‐resolution HLA allele types generated by next‐generation sequencing ...
Yvonne V. Rosario +15 more
wiley +1 more source
ZDHHC11-mediated palmitoylation of viral envelope protein restricts dengue virus replication: implication for the development of universal anti-flavivirus therapeutic strategies. [PDF]
Lai M +8 more
europepmc +1 more source
Beyond Hemostasis: Platelet Biomarkers and Vascular‐Immune Crosstalk in Dengue
Several biomarkers are associated with platelet activation during dengue virus (DENV) infection. These include serum markers (AST, ALT, ferritin), platelet surface or secreted molecules (P‐selectin, PF4, RANTES, VEGF‐A, CD40L, TREM‐1, TLT‐1), immune and endothelial markers (TREM‐1, Ang‐1, Ang‐2), and viral components such as DENV EIII.
Amanda Beatriz Adriano da Silva‐Alencar +6 more
wiley +1 more source
Proximity labelling identifies proteins associated with HSV-2 pUL21 at early and late times after infection. [PDF]
Holder SM +3 more
europepmc +1 more source

