Results 221 to 230 of about 203,793 (303)

VE‐Cadherin–Actin Regulation Promotes Mechanotransduction and Monolayer Maturation Involving a Tension‐Sensitive Intermediate State

Advanced Science, Volume 13, Issue 25, 4 May 2026.
This study investigates how endothelial monolayers balance cohesion and plasticity during mechanical stimulation. In HUVECs, shear stress induces a tension‐sensitive intermediate state in which junctional VE‐cadherin and actomyosin relaxation levels coordinate actin/integrin remodeling. This rapid, reversible state strengthens cell junctions, preserves
Jonas Franz, Maria Odenthal‐Schnittler, Jan Philip Kipcke, Jochen Seebach, Zahra Labbaf, Franziska Merten, Vesna Bojovic, Muna Taha, Johannes A. Eble, Erez Raz, Milos Galic, Hans Schnittler   +11 more
wiley   +1 more source

Impact of cellular proteases on the function of antiviral antibodies. [PDF]

J Virol
Krzypow M, Schwartz O, Bruel T, Cottignies-Calamarte A.   +3 more
europepmc   +1 more source

Nuclear Mechanotransduction Across the Metastatic Cascade: Decoding Spatiotemporal Heterogeneity in Cancer Dissemination

Advanced Science, Volume 13, Issue 25, 4 May 2026.
Tumor metastasis results from complex interactions between cancer cells and mechanical microenvironments. We propose a “nucleus‐centered, cross‐stage mechanical signal decoding” model, highlighting how nuclear mechanosensors interpret forces at different stages.
Linqi Song, Jingyang Liu, Xue Wang, Minpu Zhang, Changgang Sun   +4 more
wiley   +1 more source

Advances in Engineered Virus-Like Particles for Genome Editing and Therapy. [PDF]

BioDrugs
Son SH, Woo S, Choi A, Ahn S, Yoo HC.
europepmc   +1 more source

Dengue Virus Capsid Protein Interaction With Nucleic Acids

BioFactors, Volume 52, Issue 3, May/June 2026.
Binding of dengue virus capsid protein (DENV C) to ssDNA alters Trp fluorescence intensity, lifetime, and anisotropy, revealing structural rearrangements in the complex and suggesting a possible association with liquid–liquid phase separation (LLPS). ABSTRACT Dengue virus (DENV) transmission has greatly increased in the last decade, partly due to the ...
Nelly M. Silva, Ana S. Martins, Nina E. Karguth, Maria J. Sarmento, Francisco J. Enguita, Roland G. Huber, Ivo C. Martins, Nuno C. Santos   +7 more
wiley   +1 more source

Daidzin protects against dengue virus infection by targeting viral envelope protein

Industrial Crops and Products
Xuemei He, Bing Chen, Jingtao Yu, Gefei Peng, Yuhua Li, Zibin Lu, Jinying Ou, Jianhai Yu, Wei Zhao, Huihui Cao, Wen Li, Linzhong Yu, Junshan Liu   +12 more
openaire   +1 more source

Engagement of a Neighboring Lys Residue by a Salicylaldehyde‐Modified Glycomimetic Ligand Enables Potent and Selective Binding to DC‐SIGN Over L‐SIGN

ChemistryEurope, Volume 4, Issue 5, May 2026.
Mannose derivatives connected to the aminophilic salicylaldehyde tag show high binding affinity for C‐type lectin DC‐SIGN, favored by an imine bond with a protein's Lys residue in the ligand binding site. This reversible‐covalent binding interaction enables ligand selectivity for DC‐SIGN over the closely related L‐SIGN.
Sara Pollastri, Clara Delaunay, Giulia Antonini, Carine Froment, Michel Thépaut, Davide Pasquali, Sarah Mazzotta, Laura Belvisi, Julien Marcoux, Franck Fieschi, Alberto Dal Corso, Anna Bernardi   +11 more
wiley   +1 more source

Brefeldin A inhibits duck plague virus replication by impairing virion envelopment. [PDF]

Poult Sci
Wang X, Tian B, Liu Z, Cai D, Tian Y, Wang M, Wu Y, Yang Q, Zhang S, Zhu D, Liu M, Zhao X, Sun D, Huang J, Ou X, Wu Z, He Y, Jia R, Chen S, Cheng A.   +19 more
europepmc   +1 more source

A Genetic Reporter for Visualizing Nitroreductase Activity Using Magnetic Resonance Imaging

Chemistry–Methods, Volume 6, Issue 5, May 2026.
We introduce a reporter gene technology to noninvasively visualize bacterial nitroreductase activity. Our method utilizes a magnetic resonance imaging (MRI) reporter based on aquaporin, which is fused to a destabilizing domain, resulting in their degradation (off‐state).
Jinyang Wan, Asish N. Chacko, Emrys Xu, Kiran Kuriakose, Arnab Mukherjee   +4 more
wiley   +1 more source

S-palmitoylation and depalmitoylation at the interface of animal virus-host interactions. [PDF]

Front Cell Infect Microbiol
Xu RQ, Chen XM, Wang CR, Ma SJ, Wang PL, Chen HY.   +5 more
europepmc   +1 more source