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Iscom of viral envelope proteins protects against Aujeszky's disease

Veterinary Microbiology, 1989
An immunostimulating complex (iscom) containing the envelope proteins of pseudorabies virus (PRV) was prepared and its efficacy was evaluated in two experiments on sheep. In the first experiment, sheep were intramuscularly (i.m.) or intradermally (i.d.) vaccinated with PRV iscom doses varying between 1 and 81 micrograms. The vaccination was repeated on
B, Morein   +5 more
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On The Role of Viral Envelope Proteins in Pathogenesis

1984
The paramyxovirus envelope contains two surface glycoproteins (HN and F) and an internal non-glycosylated protein (M). The F protein is involved in viral pathogenesis in three different ways, each related to its ability to cause membrane fusion, which mediates virus penetration, cell fusion, and hemolysis. 1.
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Lysis of retroviruses with monoclonal antibodies against viral envelope proteins

Virology, 1980
Abstract Monoclonal antibodies identifying six independent antigenic determinants (epitopes) on the gp70 and p15(E) envelope proteins of murine leukemia virus were tested for their ability to lyse a panel of serologically different [3H]uridine-labeled retroviruses in the presence of complement.
S, Oroszlan, R C, Nowinski
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Epitope mapping of the gp53 envelope protein of bovine viral diarrhea virus

Virology, 1992
Epitopes recognized by nine monoclonal antibodies (mAbs) on the envelope protein, gp53, of two strains of bovine viral diarrhoea virus (NADL and Oregon C24V) were mapped by competitive binding assays and by the characterization and sequence analyses of mAb neutralization escape mutants.
D J, Paton, J P, Lowings, A D, Barrett
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Structural characterization of viral envelope proteins

2022
Infection by viruses having lipid bilayer envelopes proceeds through the fusion of the viral envelope with a membrane of the host cell. This reaction is catalyzed by viral envelope proteins, which are exposed on the virus surface. Viral envelope proteins are responsible for the two major steps in virus entry: 1)attachment to cellular receptor/s and 2 ...
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Role of the N-terminal peptides of viral envelope proteins in membrane fusion

Advanced Drug Delivery Reviews, 1999
Membrane fusion is an important biological process that is observed in a wide variety of intra and intercellular events. In this review, work done in the last few years on the molecular mechanism of viral membrane fusion is highlighted, focusing in particular on the role of the fusion peptide and the modification of the lipid bilayer structure.
Martin, Isabelle   +2 more
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Beyond the Viroporin: The Envelope Protein as a Therapeutic Target in Viral Immunomodulation

Reviews in Medical Virology
ABSTRACT In their comprehensive review, Shekhar et al. (Rev Med Virol. 2025; 35:e70067) provide a valuable synthesis of the viral envelope (E) protein's role in subverting innate immunity and its potential as a pharmacological target.
DuJiang Yang, GuoYou Wang
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A Dissection of Steps Leading to Viral Envelope Protein‐Mediated Membrane Fusion

Annals of the New York Academy of Sciences, 1991
increase in [Ca”] at the presynaptic nerve terminal sets a complex set of biochemical events in motion that finally terminates in the specific fusion of the membrane of the secretory vesicle with the plasma membrane.’ In studying the action of CaZ+ at the presynaptic terminal a distinction has to be made between processes that occur in the cytosol that
R, Blumenthal   +3 more
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Dengue viral envelope protein and histidine protonation

2009
In enveloped viruses, like flaviviruses, that enter cells via receptor-mediated endocytosis, fusion is initiated in low-pH of the endosomal vesicle. Upon appropriate triggering, the fusion protein interacts with the target membrane through a hydrophobic fusion peptide and undergoes a conformational change that drives the membrane fusion reaction1.
Yennamalli, RM   +4 more
openaire   +1 more source

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