Results 41 to 50 of about 9,793 (243)
The ubiquitin-proteasome system is required for African swine fever replication. [PDF]
PLoS ONE, 2017 Several viruses manipulate the ubiquitin-proteasome system (UPS) to initiate a productive infection. Determined viral proteins are able to change the host's ubiquitin machinery and some viruses even encode their own ubiquitinating or deubiquitinating ...
Lucía Barrado-Gil +4 more
doaj +1 more source
Recruitment of reovirus RNAs to viral factories [PDF]
, 2022 Viruses face monumental challenges when colonizing a cell. They are much smaller than the cells they infect, yet they can efficiently replicate in relatively-large complex environments.
Lee, Christopher
core
Virus-Mediated Compartmentalization of the Host Translational Machinery
mBio, 2014 Viruses require the host translational apparatus to synthesize viral proteins. Host stress response mechanisms that suppress translation, therefore, represent a significant obstacle that viruses must overcome.
Emily A. Desmet +2 more
doaj +1 more source
Viruses, 2015 Replication of the poliovirus genome is localized to cytoplasmic replication factories that are fashioned out of a mixture of viral proteins, scavenged cellular components, and new components that are synthesized within the cell due to viral manipulation/
Evan D. Rossignol +2 more
doaj +1 more source
Reovirus uses temporospatial compartmentalization to orchestrate core versus outercapsid assembly.
PLoS Pathogens, 2022 Reoviridae virus family members, such as mammalian orthoreovirus (reovirus), encounter a unique challenge during replication. To hide the dsRNA from host recognition, the genome remains encapsidated in transcriptionally active proteinaceous core capsids ...
Justine Kniert +5 more
doaj +1 more source
Function, Architecture, and Biogenesis of Reovirus Replication Neoorganelles
Viruses, 2019 Most viruses that replicate in the cytoplasm of host cells form neoorganelles that serve as sites of viral genome replication and particle assembly. These highly specialized structures concentrate viral proteins and nucleic acids, prevent the activation ...
Raquel Tenorio +6 more
doaj +1 more source
Large late viral factories enclose internal ER membranes. [PDF]
, 2016 (A) BSC-40 cells were infected with VACV strain WR for 4 h (middle panel) or 8 h (third panel) and then fixed and stained to detect DNA (DAPI), the ER membrane marker calreticulin, and the viral I3 protein.
Patrick Paszkowski (2941836) +2 more
core +1 more source
Frontiers in Plant Science, 2018 Double-stranded RNA (dsRNA) plays essential functions in many biological processes, including the activation of innate immune responses and RNA interference.
Baptiste Monsion +9 more
doaj +1 more source
Viruses, 2020 Zika virus (ZIKV; Flaviviridae) is a mosquito-borne flavivirus shown to cause fetal abnormalities collectively known as congenital Zika syndrome and Guillain-Barré syndrome in recent outbreaks.
Jamie Royle +9 more
doaj +1 more source
Ribosomal control in RNA virus-infected cells
Frontiers in Microbiology, 2022 Viruses are strictly intracellular parasites requiring host cellular functions to complete their reproduction cycle involving virus infection of host cell, viral genome replication, viral protein translation, and virion release.
Xiao Wang +3 more
doaj +1 more source