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Setting Up Shop: The Formation and Function of the Viral Factories of Cauliflower mosaic virus [PDF]
Similar to cells, viruses often compartmentalize specific functions such as genome replication or particle assembly. Viral compartments may contain host organelle membranes or they may be mainly composed of viral proteins.
J. Schoelz, S. Leisner
semanticscholar +4 more sources
Unravelling the structure of viral replication complexes at super-resolution [PDF]
During infection, many RNA viruses produce characteristic inclusion bodies that contain both viral and host components. These structures were first described over a century ago and originally termed ‘X bodies’, as their function was not immediately ...
Olga eLinnik +4 more
doaj +2 more sources
Single- and/or double-membrane viral factories?
To our current knowledge the only (+) strand RNA family following both strategies is the family Flaviviridae. It seems, however, that members of the same genus within this family follow the same strategy.
I. Romero-Brey
semanticscholar +2 more sources
Borna Disease Virus Assembles Porous Cage-like Viral Factories in the Nucleus* [PDF]
Animal-derived RNA viruses frequently generate viral factories in infected cells. However, the details of how RNA viruses build such intracellular structures are poorly understood.
Yuya Hirai +5 more
semanticscholar +3 more sources
Significance Multiple families of DNA viruses including herpesviruses amplify their genomes in nuclear sites termed replication compartments. What benefits the viruses gain by this spatial and temporal control is unclear. We have analyzed the replication
T. Nagaraju, Arthur U. Sugden, B. Sugden
semanticscholar +3 more sources
Viral proteins can aggregate into granules within host cells, known as viral factories, or viroplasms, which play a pivotal role in facilitating viral replication and shielding the viral genome from cellular defense mechanisms.
Zhiyi Wang +7 more
doaj +2 more sources
Stress granules (SGs) are membrane-less dynamic structures consisting of mRNA and protein aggregates that form rapidly in response to a wide range of environmental cellular stresses and viral infections.
Jovan Nikolic +4 more
semanticscholar +6 more sources
The Endocytic Recycling Compartment Serves as a Viral Factory for Hepatitis E Virus [PDF]
Abstract Background & Aims Although Hepatitis E virus (HEV) is the major leading cause of enterically transmitted viral hepatitis worldwide, many gaps remain in the understanding of the HEV lifecycle. Notably, viral factories induced by HEV have not been documented yet and it is currently unknown
Cyrine Bentaleb +19 more
openaire +4 more sources
Reovirus Nonstructural Protein σNS Recruits Viral RNA to Replication Organelles
The function of the mammalian orthoreovirus (reovirus) σNS nonstructural protein is enigmatic. σNS is an RNA-binding protein that forms oligomers and enhances the stability of bound RNAs, but the mechanisms by which it contributes to reovirus replication
Christopher H. Lee +8 more
doaj +1 more source

