Results 121 to 130 of about 319,921 (262)

Low-pH induced conformational changes in viral fusion proteins: implications for the fusion mechanism

open access: yesJournal of General Virology, 1995
Introduction. Entry of enveloped viruses into host cells requires binding of the virus to one or more receptors present at the host cell surface followed by fusion of the viral envelope with a cellular membrane. After binding, viruses such as paramyxoviruses, retroviruses and herpesviruses are thought to fuse directly with the plasma membrane.
Rob W.H. Ruigrok   +2 more
openaire   +2 more sources

Breaking In: Human Metapneumovirus Fusion and Entry

open access: yesViruses, 2013
Human metapneumovirus (HMPV) is a leading cause of respiratory infection that causes upper airway and severe lower respiratory tract infections. HMPV infection is initiated by viral surface glycoproteins that attach to cellular receptors and mediate ...
John V. Williams, Reagan G. Cox
doaj   +1 more source

Identification of a novel retroviral gene unique to human immunodeficiency virus type 2 and simian immunodeficiency virus SIVMAC [PDF]

open access: yes, 1988
Human and simian immunodeficiency-associated retroviruses are extraordinarily complex, containing at least five genes, tat, art, sor, R, and 3' orf, in addition to the structural genes gag, pol, and env.
Hahn, Beatrice H.   +7 more
core  

Inhibition of Viral Fusion by Interferon-Induced Transmembrane Proteins [PDF]

open access: yesBiophysical Journal, 2021
Xiangyang Guo   +4 more
openaire   +2 more sources

Role of Viral Envelope Proteins in Determining Susceptibility of Viruses to IFITM Proteins

open access: yesViruses
Interferon-induced transmembrane proteins (IFITMs) are a family of proteins which inhibit infections of various enveloped viruses. While their general mechanism of inhibition seems to be non-specific, involving the tightening of membrane structures to ...
Thomas Marceau, Martine Braibant
doaj   +1 more source

Fusion peptide induced modification of membrane organization and dynamics: Implications in developing fusion inhibitors

open access: yesChemical Physics Impact, 2023
An essential step in the entrance of enveloped viruses such as coronaviruses, the human immunodeficiency virus, and influenza is membrane fusion. A unique class of glycoprotein found on the viral envelope, known as a fusion protein, is responsible for ...
Smruti Mishra   +2 more
doaj  

Peptides from conserved regions of paramyxovirus fusion (F) proteins are potent inhibitors of viral fusion. [PDF]

open access: bronze, 1996
D.M. Lambert   +9 more
openalex   +1 more source

Relating structure to evolution in class II viral membrane fusion proteins

open access: yesCurrent Opinion in Virology, 2014
Enveloped viruses must fuse their lipid membrane to a cellular membrane to deliver the viral genome into the cytoplasm for replication. Viral envelope proteins catalyze this critical membrane fusion event. They fall into at least three distinct structural classes. Class II fusion proteins have a conserved three-domain architecture and are found in many
openaire   +4 more sources

Dynamic organization of Herpesvirus glycoproteins on the viral envelope revealed by super-resolution microscopy.

open access: yesPLoS Pathogens, 2019
The processes of cell attachment and membrane fusion of Herpes Simplex Virus 1 involve many different envelope glycoproteins. Viral proteins gC and gD bind to cellular receptors.
Frauke Beilstein   +5 more
doaj   +1 more source

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