Results 31 to 40 of about 334,138 (333)
The essential role of mitochondrial dynamics in antiviral immunity. [PDF]
, 2018 Viruses alter cellular physiology and function to establish cellular environment conducive for viral proliferation. Viral immune evasion is an essential aspect of viral persistence and proliferation.
Ahn, Dae-Gyun +3 more
core +2 more sources
The Many Mechanisms of Viral Membrane Fusion Proteins [PDF]
, 2004 Every enveloped virus fuses its membrane with a host cell membrane, thereby releasing its genome into the cytoplasm and initiating the viral replication cycle. In each case, one or a small set of viral surface transmembrane glycoproteins mediates fusion. Viral fusion proteins vary in their mode of activation and in structural class.
Earp, L. J. +3 more
openaire +2 more sources
Biomolecules, 2018 Membrane fusion proteins are responsible for viral entry into host cells—a crucial first step in viral infection. These proteins undergo large conformational changes from pre-fusion to fusion-initiation structures, and, despite differences in viral
Anna Lappala +8 more
doaj +1 more source
Inhibition of the Hantavirus Fusion Process by Predicted Domain III and Stem Peptides from Glycoprotein Gc. [PDF]
PLoS Neglected Tropical Diseases, 2016 Hantaviruses can cause hantavirus pulmonary syndrome or hemorrhagic fever with renal syndrome in humans. To enter cells, hantaviruses fuse their envelope membrane with host cell membranes.
Gonzalo P Barriga +9 more
doaj +1 more source
Structure of the Core Postfusion Porcine Endogenous Retrovirus Fusion Protein
mBio, 2022 Retroviral elements from endogenous retroviruses have functions in mammalian physiology. The best-known examples are the envelope proteins that function in placenta development and immune suppression.
Trevor T. Dean +2 more
doaj +1 more source
SARS-CoV-2 Fusion Peptide Conjugated to a Tetravalent Dendrimer Selectively Inhibits Viral Infection
Pharmaceutics, 2023 Fusion is a key event for enveloped viruses, through which viral and cell membranes come into close contact. This event is mediated by viral fusion proteins, which are divided into three structural and functional classes.
Carla Zannella +10 more
doaj +1 more source
Understanding the process of envelope glycoprotein incorporation into virions in simian and feline immunodeficiency viruses [PDF]
, 2014 The lentiviral envelope glycoproteins (Env) mediate virus entry by interacting with specific receptors present at the cell surface, thereby determining viral tropism and pathogenesis.
Affranchino, Jose Luis +1 more
core +4 more sources
Viruses, 2019 Fusion of viral and cellular membranes is a key step during the viral life cycle. Enveloped viruses trigger this process by means of specialized viral proteins expressed on their surface, the so-called viral fusion proteins.
María J. García-Murria +4 more
doaj +1 more source
Protein transduction: A novel tool for tissue regeneration [PDF]
, 2002 Tissue regeneration in humans is limited and excludes vitals organs like heart and brain. Transformation experiments with oncogenes like T antigen have shown that retrodifferentiation of the respective cells is possible but hard to control. To bypass the
Derer W. +4 more
core +1 more source
Interactions in vivo between the Vif protein of HIV-1 and the precursor (Pr55GAG) of the virion nucleocapsid proteins [PDF]
, 2009 The abnormality of viral core structure seen in vif-defective HIV-1 grown in PBMCs has suggested a role for Vif in viral morphogenesis. Using an in vivo mammalian two-hybrid assay, the interaction between Vif and the precursor (Pr55GAG) of the virion ...
A Harmache +42 more
core +1 more source