Results 31 to 40 of about 53,272 (209)

Structural Vaccinology for Viral Vaccine Design

open access: yesFrontiers in Microbiology, 2019
Although vaccines have proven pivotal against arrays of infectious viral diseases, there are still no effective vaccines against many viruses. New structural insights into the viral envelope, protein conformation, and antigenic epitopes can guide the ...
Mohd Ishtiaq Anasir, Chit Laa Poh
doaj   +1 more source

Hepatitis E Virus Infection in Voluntary Blood Donors in the Russian Federation

open access: yesViruses
Transfusion-transmitted hepatitis E virus (HEV) infection is an increasing concern in many countries. We investigated the detection rate of HEV viremia in blood donors in Russia. A total of 20,405 regular repetitive voluntary non-renumerated blood donors
Ilya A. Potemkin   +16 more
doaj   +1 more source

Viral hepatitis

open access: yesSouth African Family Practice, 2006
The hepatitis A, B, C, D and E viruses primarily target the liver to cause viral hepatitis. Hepatitis A (HAV) and E (HEV) viruses are transmitted by the faecal-oral route and cause acute viral hepatitis.
D. Brink
doaj   +1 more source

Potential of CRISPR/Cas system as emerging tools in the detection of viral hepatitis infection

open access: yesVirology Journal, 2023
Viral hepatitis, the most common cause of inflammatory liver disease, affects hundreds of millions of people worldwide. It is most commonly associated with one of the five nominal hepatitis viruses (hepatitis A–E viruses).
Howra Bahrulolum   +6 more
doaj   +1 more source

TLR agonists as vaccine adjuvants in the prevention of viral infections: an overview

open access: yesFrontiers in Microbiology, 2023
Tol-like receptor (TLR) agonists, as potent adjuvants, have gained attention in vaccine research for their ability to enhance immune responses. This study focuses on their application in improving vaccine efficacy against key viral infections, including ...
Mohammad Enamul Hoque Kayesh   +2 more
doaj   +1 more source

Development of polyepitopic immunogenic contrast against hepatitis C virus 1a-6a genotype by in silico approach

open access: yesBiomedical and Biotechnology Research Journal, 2020
Background: Hepatitis C is a viral disease associated with chronic hepatitis and hepatocellular carcinoma. Hepatitis C virus (HCV) plays a critical role in the pathogenesis of this disease.
Zeinab Dehghan   +6 more
doaj   +1 more source

The roles of different microRNAs in the regulation of cholesterol in viral hepatitis

open access: yesCell Communication and Signaling, 2023
Cholesterol plays a significant role in stabilizing lipid or membrane rafts, which are specific cellular membrane structures. Cholesterol is involved in numerous cellular processes, including regulating virus entry into the host cell.
Xuan Meng   +7 more
doaj   +1 more source

Recent advancements in combination subunit vaccine development

open access: yesHuman Vaccines & Immunotherapeutics, 2017
Viral structural proteins share a common nature of homotypic interactions that drive viral capsid formation. This natural process has been mimicked in vitro through recombinant technology to generate various virus-like particles (VLPs) and small subviral
Ming Tan, Xi Jiang
doaj   +1 more source

Liver disease during pregnancy: acute viral hepatitis

open access: yesAnnals of Hepatology, 2006
Acute viral hepatitis is the most common cause of jaundice in pregnancy. The course of most viral hepatitis infections (e.g., hepatitis A, B, C and D) is unaffected by pregnancy, however, a more severe course of viral hepatitis in pregnancy has been ...
Silvia Sookoian
doaj   +1 more source

Development of virus-like particles with inbuilt immunostimulatory properties as vaccine candidates

open access: yesFrontiers in Microbiology, 2023
The development of virus-like particle (VLP) based vaccines for human papillomavirus, hepatitis B and hepatitis E viruses represented a breakthrough in vaccine development.
Simon Collett   +25 more
doaj   +1 more source

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