Results 11 to 20 of about 623,045 (205)

Skin Viral Infections: Host Antiviral Innate Immunity and Viral Immune Evasion [PDF]

open access: yesFrontiers in Immunology, 2020
The skin is an active immune organ that functions as the first and largest site of defense to the outside environment. Serving as the primary interface between host and pathogen, the skin's early immune responses to viral invaders often determine the course and severity of infection.
Vivian Lei   +8 more
openaire   +3 more sources

Gut Leakage of Fungal‐Related Products: Turning Up the Heat for HIV Infection

open access: yesFrontiers in Immunology, 2021
The intestinal epithelial layer serves as a physical and functional barrier between the microbiota in the lumen and immunologically active submucosa. Th17 T-cell function protects the gut epithelium from aggression from microbes and their by-products ...
Stéphane Isnard   +13 more
doaj   +1 more source

What role for cellular metabolism in the control of hepatitis viruses?

open access: yesFrontiers in Immunology, 2022
Hepatitis B, C and D viruses (HBV, HCV, HDV, respectively) specifically infect human hepatocytes and often establish chronic viral infections of the liver, thus escaping antiviral immunity for years.
Olivier Diaz   +5 more
doaj   +1 more source

Viral hepatitis prevention by immunization [PDF]

open access: yesJornal de Pediatria, 2006
To present an updated review and criticism of viral hepatitis A and B prevention by immunization.Review of medical articles obtained from the MEDLINE database. The most recent and representative articles on the subject (2000-2006) were selected. The Centers for Disease Control and Prevention (CDC), American Academy of Pediatrics (AAP), Brazilian ...
Ferreira, Cristina Helena Targa   +1 more
openaire   +3 more sources

Engineered CD4 T cells expressing a membrane anchored viral inhibitor restrict HIV-1 through cis and trans mechanisms

open access: yesFrontiers in Immunology, 2023
HIV-1 infection of target cells can occur through either cell-free virions or cell-cell transmission in a virological synapse, with the latter mechanism of infection reported to be 100- to 1,000-fold more efficient.
Weiming Wang   +9 more
doaj   +1 more source

Viral miRNAs and immune evasion [PDF]

open access: yesBiochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2011
Viral miRNAs, ~22nt RNA molecules which post-transcriptionally regulate gene expression, are emerging as important tools in immune evasion. Viral infection is a complex process that requires immune evasion in order to establish persistent life-long infection of the host.
Department of Molecular Genetics and Microbiology, University of Florida Mowry Road, Gainesville, FL 32610, USA ( host institution )   +2 more
openaire   +3 more sources

Immune Checkpoints in Viral Infections [PDF]

open access: yesViruses, 2020
As evidence has mounted that virus-infected cells, such as cancer cells, negatively regulate the function of T-cells via immune checkpoints, it has become increasingly clear that viral infections similarly exploit immune checkpoints as an immune system escape mechanism.
Huiming Cai   +11 more
openaire   +3 more sources

Simian Immunodeficiency Virus Infection of Rhesus Macaques Results in Delayed Zika Virus Clearance

open access: yesmBio, 2019
Flaviviruses are controlled by adaptive immune responses but are exquisitely sensitive to interferon-stimulated genes (ISGs). How coinfections, particularly simian immunodeficiency viruses (SIVs), that induce robust ISG signatures influence flavivirus ...
Carol L. Vinton   +13 more
doaj   +1 more source

Using the nonhuman primate model of HCMV to guide vaccine development. [PDF]

open access: yes, 2014
The natural history of human cytomegalovirus (HCMV) is inextricably associated with mucosal surfaces. The vast preponderance of primary infections occur following mucosal exposure to infectious virions, and the high seroprevalence of HCMV throughout the ...
Barry, Peter A, Deere, Jesse D
core   +3 more sources

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