Results 31 to 40 of about 119,468 (286)

RNA-binding protein immunoprecipitation as a tool to investigate plant miRNA processing interference by regulatory proteins of diverse origin [PDF]

open access: yes, 2018
Background: Due to the nature of viral RNA genomes, RNA viruses depend on many RNA-binding proteins (RBP) of viral and host origin for replication, dissemination and evasion of host RNA degradation pathways.
Garcia, Maria Laura   +2 more
core   +2 more sources

Functional organization of cytoplasmic inclusion bodies in cells infected by respiratory syncytial virus

open access: yesNature Communications, 2017
Respiratory syncytial virus (RSV) induces formation of inclusion bodies (IBs) sheltering viral RNA synthesis. Here, Rincheval et al. identify highly dynamic IB-associated granules (IBAGs) that accumulate newly synthetized viral mRNA and the viral M2-1 ...
Vincent Rincheval   +9 more
doaj   +1 more source

Pur-Alpha Induces JCV Gene Expression and Viral Replication by Suppressing SRSF1 in Glial Cells. [PDF]

open access: yesPLoS ONE, 2016
OBJECTIVE:PML is a rare and fatal demyelinating disease of the CNS caused by the human polyomavirus, JC virus (JCV), which occurs in AIDS patients and those on immunosuppressive monoclonal antibody therapies (mAbs).
Ilker Kudret Sariyer   +3 more
doaj   +1 more source

Human Respiratory Syncytial Virus Infection in a Human T Cell Line Is Hampered at Multiple Steps

open access: yesViruses, 2021
Human respiratory syncytial virus (HRSV) is the most frequent cause of severe respiratory disease in children. The main targets of HRSV infection are epithelial cells of the respiratory tract, and the great majority of the studies regarding HRSV ...
Ricardo de Souza Cardoso   +10 more
doaj   +1 more source

Innate immune basis for rift valley fever susceptibility in mouse models [PDF]

open access: yes, 2017
Rift Valley fever virus (RVFV) leads to varied clinical manifestations in animals and in humans that range from moderate fever to fatal illness, suggesting that host immune responses are important determinants of the disease severity. We investigated the
Bruhns, Pierre   +7 more
core   +3 more sources

Modulation of plant autophagy during pathogen attack [PDF]

open access: yes, 2017
In plants, the highly conserved catabolic process of autophagy has long been known as a means of maintaining cellular homeostasis and coping with abiotic stress conditions. Accumulating evidence has linked autophagy to immunity against invading pathogens,
Bozkurt, Tolga O.   +9 more
core   +1 more source

An Outbreak of the Saddled Prominent Caterpillar, \u3ci\u3eHeteocampa Guttivitta\u3c/i\u3e (Lepidoptera: Notodontidae) on Beaver Island, Michigan [PDF]

open access: yes, 2017
(excerpt) In 1975 and 1976 an outbreak of the saddled prominent caterpillar, Heterocarnpa guttivitta (Walker) was observed in Beech-Maple climax forests on Beaver Island, Michigan.
Foran, Jeffry, Loesch, Alice
core   +2 more sources

Human Cytomegalovirus. Studies on the Mechanism of Viral Gytopathology and Inclusion Body Formation.

open access: yesExperimental Biology and Medicine, 1967
SummaryWhen cultured human fetal fi-broblasts were infected by human cytomegalo-virus, virus-induced morphologic changes consisting of cytopathology, intracytoplasmic and intranuclear inclusion bodies developed during a 72-hour period. Thus, in this system, virus-induced cell changes followed closely upon viral multiplication.
R M, McAllister   +2 more
openaire   +2 more sources

Structure of the N-RNA/P interface indicates mode of L/P recruitment to the nucleocapsid of human metapneumovirus

open access: yesNature Communications, 2023
Human metapneumovirus (HMPV) is a major cause of respiratory illness in young children. The HMPV polymerase (L) binds an obligate cofactor, the phosphoprotein (P).
Jack D. Whitehead   +7 more
doaj   +1 more source

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