Inclusion bodies of human parainfluenza virus type 3 inhibit antiviral stress granule formation by shielding viral RNAs. [PDF]
PLoS Pathogens, 2018 Viral invasion triggers the activation of the host antiviral response. Besides the innate immune response, stress granules (SGs) also act as an additional defense response to combat viral replication. However, many viruses have evolved various strategies
Zhulong Hu +5 more
doaj +3 more sources
Molluscum Contagiosum Complicated With an Epidermal Cyst: A Case Report [PDF]
Clinical Case ReportsMolluscum contagiosum (MC) is a viral infection that primarily affects pediatric patients, sexually active young adults, and immunocompromised individuals of all ages.
Ruixian Niu +6 more
doaj +2 more sources
Liquid-liquid phase separation mediated immune evasion of respiratory syncytial virus against oligoadenylate synthetase-RNase L pathway. [PDF]
PLoS PathogensRespiratory syncytial virus (RSV) infection is the major cause of severe respiratory illnesses in infants and older adults. RSV forms phase-separated biomolecular condensates called inclusion bodies (IBs), which serve as hubs for viral replication ...
Woo Yeon Hwang +3 more
doaj +2 more sources
Involvement of L polymerase and heat shock proteins in the biogenesis of viral circular RNAs derived from respiratory syncytial virus [PDF]
mBioCircular RNAs (circRNAs) are new members of noncoding RNAs that have gained increased attention, and reports on viral circRNAs and their functions continue to emerge in recent years.
Mingzhen Lin +11 more
doaj +2 more sources
N6 -Methyladenosine Negatively Regulates Human Respiratory Syncytial Virus Replication
Frontiers in Cell and Developmental Biology, 2021 N6-methyladenosine (m6A) is the most abundant internal modification described in eukaryotic mRNA and several viral RNA including human respiratory syncytial virus (HRSV).
Fabian Figueroa +15 more
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Toll-like receptor 3 (TLR3) plays a major role in the formation of rabies virus Negri Bodies. [PDF]
PLoS Pathogens, 2009 Human neurons express the innate immune response receptor, Toll-like receptor 3 (TLR3). TLR3 levels are increased in pathological conditions such as brain virus infection.
Pauline Ménager +8 more
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Aquareovirus NS80 recruits viral proteins to its inclusions, and its C-terminal domain is the primary driving force for viral inclusion formation. [PDF]
PLoS ONE, 2013 Cytoplasmic inclusion bodies formed in reovirus-infected cells are the sites of viral replication and assembly. Previous studies have suggested that the NS80 protein of aquareovirus may be involved in the formation of viral inclusion bodies.
Ling Shao +4 more
doaj +1 more source
Cytomegalovirus-associated esophageal ulcer in an immunocompetent infant: When should ganciclovir be administered? [PDF]
Korean Journal of Pediatrics, 2012 Cytomegalovirus (CMV)-associated esophageal ulcer is rare in immunocompetent infants. The presence of inclusion bodies and immunohistochemical staining for CMV in biopsy specimens obtained during esophagogastroduodenoscopy (EGD) indicate that such ulcers
Hyo-Jeong Jang +2 more
doaj +1 more source
The N-Terminal of Aquareovirus NS80 Is Required for Interacting with Viral Proteins and Viral Replication. [PDF]
PLoS ONE, 2016 Reovirus replication and assembly occurs within viral inclusion bodies that formed in specific intracellular compartments of cytoplasm in infected cells.
Jie Zhang +4 more
doaj +1 more source
Microbiology Spectrum, 2023 The vitamin D receptor (VDR) plays a pivotal role in the biological actions of vitamin D (VitD). However, little is known about the functions of VDR in the production of viral inclusion bodies (VIBs). Using a representative strain of grass carp reovirus (
Yun Jie Song +6 more
doaj +1 more source