Results 1 to 10 of about 9,076 (199)

Cell surface heparan sulfate is an attachment receptor for grass carp reovirus [PDF]

iScience
Summary: Grass carp reovirus (GCRV) causes hemorrhagic disease in grass carp, leading to significant economic losses in China’s aquaculture. However, the cellular receptors responsible for the initiation of GCRV infection remain unclear.
Qian Wang, Hanyue Wang, Xuyang Wang, Cheng Yang, Yongming Li, Lanjie Liao, Zuoyan Zhu, Yaping Wang, Libo He   +8 more
doaj   +7 more sources

Type II Grass Carp Reovirus Rapidly Invades Grass Carp (Ctenopharyngodon idella) via Nostril–Olfactory System–Brain Axis, Gill, and Skin on Head [PDF]

Viruses, 2023
Type II grass carp reovirus (GCRV-II) with high pathogenicity and infectivity causes severe hemorrhagic disease, which leads to extensive death in the grass carp and black carp aquaculture. However, the early invasion portal remains unclear.
Wentao Zhu, Meihua Qiao, Meidi Hu, Xingchen Huo, Yongan Zhang, Jianguo Su   +5 more
doaj   +5 more sources

Rapid detection of grass carp reovirus type 1 using RPA-based test strips combined with CRISPR Cas13a system [PDF]

Frontiers in Microbiology, 2023
IntroductionDue to the existence of grass carp reovirus (GCRV), grass carp hemorrhagic disease occurs frequently, and its high pathogenicity and infectivity are great challenges to the aquaculture industry.
Huaming Li, Xinyue Cao, Ruige Chen, Min Guang, Mengran Xu, Xiaomin Wu, Rongrong Yang, Liancheng Lei, Fuxian Zhang   +8 more
doaj   +6 more sources

Recombinant Baculovirus-Produced Grass Carp Reovirus Virus-Like Particles as Vaccine Candidate That Provides Protective Immunity against GCRV Genotype II Infection in Grass Carp [PDF]

Vaccines, 2021
Grass carp reovirus (GCRV) leads to severe hemorrhagic disease in grass carp (Ctenopharyngodon idella) and causes economic losses in grass carp aquaculture.
Jiyuan Yin, Qing Wang, Yingying Li
exaly   +8 more sources

Recombinant Lactococcus lactis Expressing Grass Carp Reovirus VP6 Induces Mucosal Immunity Against Grass Carp Reovirus Infection [PDF]

Frontiers in Immunology, 2022
Grass carp haemorrhagic disease caused by grass carp reovirus II is a serious disease of the aquaculture industry and vaccination is the only effective method of GCRV protection.
Nan Wang, Jiahao Li, Yajun Wang, Yingying Wang, Defeng Zhang, Cunbin Shi, Yingying Li, Sven M. Bergmann, Xubing Mo, Jiyuan Yin, Qing Wang   +10 more
doaj   +4 more sources

ATG5 negatively regulates grass carp reovirus-induced immune-inflammatory response by degrading RIG-I and MDA5 [PDF]

Journal of Virology
Grass carp reovirus (GCRV) is the most virulent aquareovirus, inducing hemorrhagic disease that results in significant economic losses for the grass carp aquaculture industry in China.
Pengfei Chu, Yingying Wang, Jian Shen, Yaping Wang, Guobin Chang, Libo He   +5 more
doaj   +3 more sources

Piscine Vitamin D Receptors Vdra/Vdrb in the Absence of Vitamin D Are Utilized by Grass Carp Reovirus for Promoting Viral Replication [PDF]

Microbiology Spectrum, 2023
The vitamin D receptor (VDR) plays a pivotal role in the biological actions of vitamin D (VitD). However, little is known about the functions of VDR in the production of viral inclusion bodies (VIBs). Using a representative strain of grass carp reovirus (
Yun Jie Song, Jie Zhang, Jun Xiao, Hao Feng, Zhen Xu, Pin Nie, Ming Xian Chang   +6 more
doaj   +3 more sources

Grass carp reovirus VP4 manipulates TOLLIP to degrade STING for inhibition of IFN production [PDF]

Journal of Virology
Although fish possess an effective interferon (IFN) system to defend against viral infection, grass carp reovirus (GCRV) still causes epidemic hemorrhagic disease and tremendous economic loss in grass carp.
Yang-Yang Wang, Xue-Li Wang, Zhuo-Cong Li, Can Zhang, Xiao Xu, Bao-Jie Cui, Meng-Ze Tian, Chu-Jing Zhou, Na Xu, Yue Wu, Xiao-Li Yang, Dan-Dan Chen, Long-Feng Lu, Shun Li   +13 more
doaj   +3 more sources

Grass carp reovirus VP56 and VP35 induce formation of viral inclusion bodies for replication [PDF]

iScience, 2023
Summary: Viral inclusion bodies (VIBs) are subcellular structures required for efficient viral replication. How type II grass carp reovirus (GCRV-II), the mainly prevalent strain, forms VIBs is unknown.
Chu Zhang, Hui Wu, Hao Feng, Yong-An Zhang, Jiagang Tu   +4 more
doaj   +3 more sources

Comparative Transcriptomics Analysis Reveals Unique Immune Response to Grass Carp Reovirus Infection in Barbel Chub (Squaliobarbus curriculus) [PDF]

Biology
Grass carp (Ctenopharyngodon idella) and barbel chub (Squaliobarbus curriculus)—both Leuciscinae subfamily species—demonstrate differences in grass carp reovirus (GCRV) infection resistance.
Yuhong Huang, Xiaodong Wang, Zhao Lv, Xudong Hu, Baohong Xu, Hong Yang, Tiaoyi Xiao, Qiaolin Liu   +7 more
doaj   +3 more sources