Results 1 to 10 of about 719 (120)

Recombinant Lactococcus lactis Expressing Grass Carp Reovirus VP6 Induces Mucosal Immunity Against Grass Carp Reovirus Infection [PDF]

Frontiers in Immunology, 2022
Grass carp haemorrhagic disease caused by grass carp reovirus II is a serious disease of the aquaculture industry and vaccination is the only effective method of GCRV protection.
Nan Wang, Jiahao Li, Yajun Wang, Yingying Wang, Defeng Zhang, Cunbin Shi, Yingying Li, Sven M. Bergmann, Xubing Mo, Jiyuan Yin, Qing Wang   +10 more
doaj   +2 more sources

Identification, Virulence, and Molecular Characterization of a Recombinant Isolate of Grass Carp Reovirus Genotype I [PDF]

Viruses, 2021
The hemorrhagic disease of grass carp (HDGC) caused by grass carp reovirus (GCRV) still poses a great threat to the grass carp industry. Isolation and identification of the GCRV genotype I (GCRV-I) has been rarely reported in the past decade.
Weiwei Zeng, Sven M. Bergmannc, Hanxu Dong, Ying Yang, Minglin Wu, Hong Liu, Yanfeng Chen, Hua Li   +7 more
doaj   +2 more sources

Piscine Vitamin D Receptors Vdra/Vdrb in the Absence of Vitamin D Are Utilized by Grass Carp Reovirus for Promoting Viral Replication [PDF]

Microbiology Spectrum, 2023
The vitamin D receptor (VDR) plays a pivotal role in the biological actions of vitamin D (VitD). However, little is known about the functions of VDR in the production of viral inclusion bodies (VIBs). Using a representative strain of grass carp reovirus (
Yun Jie Song, Jie Zhang, Jun Xiao, Hao Feng, Zhen Xu, Pin Nie, Ming Xian Chang   +6 more
doaj   +2 more sources

Type II Grass Carp Reovirus Rapidly Invades Grass Carp (Ctenopharyngodon idella) via Nostril–Olfactory System–Brain Axis, Gill, and Skin on Head [PDF]

Viruses, 2023
Type II grass carp reovirus (GCRV-II) with high pathogenicity and infectivity causes severe hemorrhagic disease, which leads to extensive death in the grass carp and black carp aquaculture. However, the early invasion portal remains unclear.
Wentao Zhu, Meihua Qiao, Meidi Hu, Xingchen Huo, Yongan Zhang, Jianguo Su   +5 more
doaj   +2 more sources

Grass Carp Reovirus Induces Formation of Lipid Droplets as Sites for Its Replication and Assembly [PDF]

mBio, 2022
Grass carp is an important commercial fish in China that is plagued by various diseases, especially the hemorrhagic disease induced by grass carp reovirus (GCRV).
Libo He, Qian Wang, Xinyu Liang, Hanyue Wang, Pengfei Chu, Cheng Yang, Yongming Li, Lanjie Liao, Zuoyan Zhu, Yaping Wang   +9 more
doaj   +2 more sources

Isolation, Identification, and Genomic Analysis of a Novel Reovirus from Healthy Grass Carp and Its Dynamic Proliferation In Vitro and In Vivo

Viruses, 2021
A new grass carp reovirus (GCRV), healthy grass carp reovirus (HGCRV), was isolated from grass carp in 2019. Its complete genome sequence was determined and contained 11 dsRNAs with a total size of 23,688 bp and 57.2 mol% G+C content, encoding 12 ...
Wenzhi Liu, Yong Zhou, Yan Meng
exaly   +3 more sources

Rapid detection of grass carp reovirus type 1 using RPA-based test strips combined with CRISPR Cas13a system [PDF]

Frontiers in Microbiology, 2023
IntroductionDue to the existence of grass carp reovirus (GCRV), grass carp hemorrhagic disease occurs frequently, and its high pathogenicity and infectivity are great challenges to the aquaculture industry.
Huaming Li, Xinyue Cao, Ruige Chen, Min Guang, Mengran Xu, Xiaomin Wu, Rongrong Yang, Liancheng Lei, Fuxian Zhang   +8 more
doaj   +2 more sources

Cell surface heparan sulfate is an attachment receptor for grass carp reovirus [PDF]

iScience
Summary: Grass carp reovirus (GCRV) causes hemorrhagic disease in grass carp, leading to significant economic losses in China’s aquaculture. However, the cellular receptors responsible for the initiation of GCRV infection remain unclear.
Qian Wang, Hanyue Wang, Xuyang Wang, Cheng Yang, Yongming Li, Lanjie Liao, Zuoyan Zhu, Yaping Wang, Libo He   +8 more
doaj   +2 more sources

Autophagy Inhibits Grass Carp Reovirus (GCRV) Replication and Protects Ctenopharyngodon idella Kidney (CIK) Cells from Excessive Inflammatory Responses after GCRV Infection [PDF]

Biomolecules, 2020
Autophagy is an essential and highly conserved process in mammals, which is critical to maintaining physiological homeostasis, including cell growth, development, repair, and survival.
Pengfei Chu, Libo He, Rong Huang, Lanjie Liao, Yongming Li, Zuoyan Zhu, Wei Hu, Yaping Wang   +7 more
doaj   +2 more sources

ATG5 negatively regulates grass carp reovirus-induced immune-inflammatory response by degrading RIG-I and MDA5 [PDF]

Journal of Virology
Grass carp reovirus (GCRV) is the most virulent aquareovirus, inducing hemorrhagic disease that results in significant economic losses for the grass carp aquaculture industry in China.
Pengfei Chu, Yingying Wang, Jian Shen, Yaping Wang, Guobin Chang, Libo He   +5 more
doaj   +2 more sources