Results 41 to 50 of about 1,577 (195)

Biochemical profiling of the protein encoded by grass carp reovirus genotype II. [PDF]

iScience
In this study, we obtained the whole genome sequence of GCRV-DY197 and investigated the localization, post-translational modifications, and host interactions of the 11 viral proteins encoded by GCRV-DY197 in grass carp ovary (GCO) cells. The whole genome sequence is 24,704 kb and contains 11 segments (S1-S11).
Liu M, Xu C, Zhou Y, Xue M, Jiang N, Li Y, Huang Z, Meng Y, Liu W, Kong X, Fan Y.   +10 more
europepmc   +4 more sources

GCRV 096 VP6 protein and its impacts on GCRV replication with different genotypes in CIK cells

Aquaculture and Fisheries, 2018
Grass carp reovirus (GCRV) is the causative agent of grass carp hemorrhagic disease, which has detrimental effects on the grass carp aquaculture industry. There are four known genotypes of GCRV and strains of different GCRV genotypes differ greatly.
Xiuying Yan, Lingfang Xiong, Jie Li, Ya Wang, Zaohe Wu, Jichang Jian, Yu Ding   +6 more
doaj   +1 more source

Gig1, a novel antiviral effector involved in fish interferon response [PDF]

, 2014
Vertebrate interferon (IFN) response defenses against viral infection through the induction of hundreds of IFN-stimulated genes (ISGs). Most ISGs are conserved across vertebrates; however, little is known about the species-specific ISGs.
Chen, Chen, Gui, Jian-Fang, Jiang, Jun, Sun, Fan, Wang, Bing, Zhang, Jun, Zhang, YB (reprint author), Univ Chinese Acad Sci, Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Peoples R China., Zhang, Yi-Bing   +7 more
core   +1 more source

Genome-wide DNA methylation reveals potential epigenetic mechanism of age-dependent viral susceptibility in grass carp

Immunity & Ageing, 2022
Background Grass carp are an important farmed fish in China that are infected by many pathogens, especially grass carp reovirus (GCRV). Notably, grass carp showed age-dependent susceptibility to GCRV; that is, grass carp not older than one year were ...
Libo He, Xinyu Liang, Qian Wang, Cheng Yang, Yongming Li, Lanjie Liao, Zuoyan Zhu, Yaping Wang   +7 more
doaj   +1 more source

The use of an in vitro microneutralization assay to evaluate the potential of recombinant VP5 protein as an antigen for vaccinating against Grass carp reovirus [PDF]

, 2011
Background Grass carp reovirus (GCRV) is the causative pathogen of grass carp hemorrhagic disease, one of the major diseases damaging grass carp Ctenopharyngon idellus breeding industry in China.
Yongxing He, Hongxu Xu, Qian Yang, Dan Xu, Liqun Lu   +4 more
core   +1 more source

Multi-Omics Sequencing Provides Insights Into Age-Dependent Susceptibility of Grass Carp (Ctenopharyngodon idellus) to Reovirus

Frontiers in Immunology, 2021
Grass carp (Ctenopharyngodon idellus) is an important aquaculture species in China that is affected by serious diseases, especially hemorrhagic disease caused by grass carp reovirus (GCRV). Grass carp have previously shown age-dependent susceptibility to
Libo He, Libo He, Denghui Zhu, Denghui Zhu, Xinyu Liang, Xinyu Liang, Yongming Li, Lanjie Liao, Cheng Yang, Rong Huang, Zuoyan Zhu, Yaping Wang, Yaping Wang   +12 more
doaj   +1 more source

Isolation and expression of grass carp toll-like receptor 5a (CiTLR5a) and 5b (CiTLR5b) gene involved in the response to flagellin stimulation and grass carp reovirus infection [PDF]

, 2015
Toll-like receptor 5 (TLR5), a member of Toll-like receptors (TLRs) family and is responsible for the bacterial flagellin recognition in vertebrates, play an important role in innate immunity.
He, Libo, Jang, Songhun, Ji, Myonghuan, Jiang, Yao, Ju, Changsong, Li, Yongming, Liao, Lanjie, Pei, Yongyan, Wang, Yaping, Wang, YP (reprint author), Chinese Acad Sci, Inst Hydrobiol, Wuhan 430072, Peoples R China., Zhu, Zuoyan   +10 more
core   +1 more source

Molecular and antigenic characterization of Piscine orthoreovirus (PRV) from rainbow trout (Oncorhynchus mykiss) [PDF]

, 2018
Piscine orthoreovirus (PRV-1) causes heart and skeletal muscle inflammation (HSMI) in farmed Atlantic salmon (Salmo salar). Recently, a novel PRV (formerly PRV-Om, here called PRV-3), was found in rainbow trout (Oncorhynchus mykiss) with HSMI-like ...
Cuenca, Argelia, Dhamotharan, Kannimuthu, Krudtaa Dahle, Maria, Markussen, Turhan, Nyman, Ingvild B., Olsen, Anne Berit, Rimstad, Espen, Tengs, Torstein, Vendramin, Niccolò, Wessel, Øystein   +9 more
core   +2 more sources

Nutrigenomics and immune function in fish : new insights from omics technologies [PDF]

, 2017
This study was funded by BBSRC grant BB/M026604/1.Peer reviewedPublisher ...
Krol, Elzbieta, Martin, Samuel A. M.
core   +1 more source

Oncolytic reovirus as a combined antiviral and anti-tumour agent for the treatment of liver cancer [PDF]

, 2018
Objective: Oncolytic viruses (OVs) represent promising, proinflammatory cancer treatments. Here, we explored whether OV-induced innate immune responses could simultaneously inhibit HCV while suppressing hepatocellular carcinoma (HCC).
Abigail Bloy, Adam Peckham-Cooper, Adel Samson, Alan Melcher, Elizabeth Appleton, Fiona Errington-Mais, Franssen, Gerard Nuovo, Giles Toogood, Hagan, Hsu, Jebar, Karen Scott, Kevin Harrington, Lao, Matthew Coffey, Matthew J Bentham, Peter Selby, Rajiv Dave, Reig, Richard Vile, Robert A Adair, Seishi Nagamori, Stephen Griffin, Utsunomiya, Yamashita   +25 more
core   +1 more source