Results 61 to 70 of about 1,577 (195)

Diversification of the expanded teleost-specific toll-like receptor family in Atlantic cod, Gadus morhua. [PDF]

open access: yes, 2012
BACKGROUND: Toll-like receptors (Tlrs) are major molecular pattern recognition receptors of the innate immune system. Atlantic cod (Gadus morhua) is the first vertebrate known to have lost most of the mammalian Tlr orthologues, particularly all bacterial
Dopazo, Joaquin   +3 more
core   +2 more sources

Deep Illumina sequencing reveals conserved and novel microRNAs in grass carp in response to grass carp reovirus infection [PDF]

open access: yesBMC Genomics, 2017
The grass carp hemorrhagic disease caused by the grass carp reovirus (GCRV) is a major disease that hampers the development of grass carp aquaculture. The mechanism underlying GCRV pathogenesis and hemorrhagic symptoms is still unknown. MicroRNAs (miRNAs) are key regulators involved in various biological processes. The aim of this study was to identify
He, Libo   +7 more
openaire   +2 more sources

Protection of teleost fish against infectious diseases through oral administration of vaccines: Update 2021 [PDF]

open access: yes, 2021
Immersion and intraperitoneal injection are the two most common methods used for the vaccination of fish. Because both methods require that fish are handled and thereby stressed, oral administration of vaccines as feed supplements is desirable.
Bøgwald, Jarl, Dalmo, Roy Ambli
core   +1 more source

Global and Complement Gene-Specific DNA Methylation in Grass Carp after Grass Carp Reovirus (GCRV) Infection. [PDF]

open access: yesInt J Mol Sci, 2018
Grass carp reovirus (GCRV) causes huge economic loss to the grass carp cultivation industry but the mechanism remains largely unknown. In this study, we investigated the global and complement gene-specific DNA methylation in grass carp after GCRV infection aimed to uncover the mechanism underlying GCRV infection.
Xiong L   +7 more
europepmc   +4 more sources

Novel Duck Orthoreovirus Induces Ferroptosis in HD11 Cells by Hijacking Cellular Iron Metabolism and Promoting Iron Accumulation

open access: yesTransboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Novel duck orthoreovirus (NDRV) infection induces severe splenic necrosis in ducks, resulting in a cascade of detrimental consequences, including immunosuppression, secondary infections, and diminished vaccine efficacy. Avian orthoreovirus (ARV) exhibits high tropism for macrophages, with splenic macrophages being identified as the primary target cells
Hongzhi Wang   +6 more
wiley   +1 more source

The effects of GCRV on various tissues of grass carp (Ctenopharyngodon idella) and identification of differential interferon-stimulating genes (ISGs) through muscle transcriptome analysis

open access: yesEcotoxicology and Environmental Safety
Grass carp hemorrhagic disease is caused by the grass carp reovirus (GCRV). The disease spreads rapidly and has a high fatality rate, which seriously affects grass carp culture. Moreover, the molecular mechanisms underlying grass carp hemorrhagic disease
Ziquan Yang   +5 more
doaj   +1 more source

Transcriptome analysis of head kidney in grass carp and discovery of immune-related genes

open access: yesBMC Veterinary Research, 2012
Background Grass carp (Ctenopharyngodon idella) is one of the most economically important freshwater fish, but its production is often affected by diseases that cause serious economic losses.
Chen Jin   +6 more
doaj   +1 more source

Characterization of IL-22 Bioactivity and IL-22-Positive Cells in Grass Carp Ctenopharyngodon idella

open access: yesFrontiers in Immunology, 2020
Interleukin (IL)-22 plays an important role in regulating inflammation and clearance of infectious pathogens. IL-22 homologs have been discovered in fish, but the functions and sources of IL-22 have not been fully characterized.
Yibin Yang   +27 more
doaj   +1 more source

Structure and function of S9 segment of grass carp reovirus Anhui strain. [PDF]

open access: yesVirusdisease, 2017
A highly virulent grass carp reovirus (GCRV) strain, named GCRV-AH528, was recently purified from a diseased grass carp with hemorrhage disease in Anhui, China. GCRV-AH528 S9 segment was 1320 nucleotides in length and encoded a 418 amino acid VP6 protein.
Wu M   +6 more
europepmc   +4 more sources

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