Results 81 to 90 of about 1,577 (195)

Carbon‐Based Nanomaterials for Antiviral Applications

Advanced Functional Materials, Volume 34, Issue 38, September 18, 2024.
Carbon‐based nanomaterials (CBNs), including fullerenes, carbon dots, graphene, and their derivatives, show promise as antiviral tools in the antimicrobial resistance era. They exhibit broad‐spectrum antiviral activity with a low risk of resistance development. CBNs also enhance efficacy under light exposure and support antiviral immune responses. CBNs
Ángel Serrano‐Aroca, Kazuo Takayama, Yogendra Kumar Mishra, Cesar de la Fuente‐Nunez   +3 more
wiley   +1 more source

Molecular characterization of nonstructural protein NS38 of grass carp reovirus

Virologica Sinica, 2010
Viral nonstructural proteins in both enveloped and non-enveloped viruses play important roles in viral replication. Protein NS38 of Grass carp reovirus (GCRV), has been deduced to be a non-structural protein, and, consistent with other reoviruses, is considered to cooperate with the NS80 protein in viral particle assembly.
Ling, Shao, Chao, Fan, Ewa, Maj, Qin, Fang   +3 more
openaire   +3 more sources

Antibodies against outer-capsid proteins of grass carp reovirus expressed in E. coli are capable of neutralizing viral infectivity [PDF]

, 2011
Background Grass carp reovirus (GCRV), which causes severe infectious outbreaks of hemorrhagic disease in aquatic animals, is a highly pathogenic agent in the Aquareovirus genus of family Reoviridae.
Ling Shao, Xiaoyun Sun, Qin Fang
core   +2 more sources

Further diversity in the origins of fish antifreeze proteins

The FEBS Journal, Volume 291, Issue 18, Page 4024-4026, September 2024.
Shifts in environmental conditions can impose strong selection for adaptive traits. During the Cenozoic era, as the oceans cooled, many marine teleost fish species were at risk of freezing. This led to the independent emergence of distinct ice‐binding antifreeze proteins (AFPs).
Kathryn Vanya Ewart
wiley   +1 more source

Zebrafish foxo3b Negatively Regulates Antiviral Response through Suppressing the Transactivity of irf3 and irf7 [PDF]

, 2016
Forkhead box O (FOXO)3, a member of the FOXO family of transcription factors, plays key roles in various cellular processes, including development, longevity, reproduction, and metabolism.
Cai, Xiaolian, Liu, Xing, Xiao, Wuhan, Xu, Chenxi, Zhang, Dawei   +4 more
core   +1 more source

Optimising commercial traits through gene editing in aquaculture: Strategies for accelerating genetic improvement

Reviews in Aquaculture, Volume 16, Issue 3, Page 1127-1159, June 2024.
Abstract Aquaculture is one of the fastest‐growing food production sectors. As the global human population continues to increase and further pressure is added to the prospects of achieving global food security, aquaculture is expected to play an integral role in meeting future nutrition demands.
Megan N. Moran, D. B. Jones, S. A. Jensen, R. Marcoli, D. R. Jerry   +4 more
wiley   +1 more source

Suppression of RNA interference pathway in vitro by Grass carp reovirus

Virologica Sinica, 2012
The means of survival of genomic dsRNA of reoviruses from dsRNA-triggered and Dicer-initiated RNAi pathway remains to be defined. The present study aimed to investigate the effect of Grass carp reovirus (GCRV) replication on the RNAi pathway of grass carp kidney cells (CIK).
Shuai, Guo, Dan, Xu, Hong-xu, Xu, Tu, Wang, Jia-le, Li, Li-qun, Lu   +5 more
openaire   +3 more sources

DEAD-box helicase gcDDX56 disrupts IRF3 nuclear import complex and promotes nuclear IRF3 degradation for enhancing GCRV replication

Journal of Virology
DEAD-box helicases play multifaceted roles in antiviral immunity, acting as both viral sensors and regulators of interferon (IFN) signaling. However, the role of DDX56 in teleost antiviral immunity remains poorly characterized.
Li Li Xiao, Yang Chen, Jie Zhang, Jun Xiao, Hao Feng, Ming Xian Chang   +5 more
doaj   +1 more source

A plasmid containing CpG ODN as vaccine adjuvant against grass carp reovirus in grass carp Ctenopharyngodon idella. [PDF]

Oncotarget, 2017
CpG oligodeoxynucleotides (ODNs) are proved to have strong immune stimulatory activity. Plasmids containing CpG ODNs could be conveniently and low-costly used as vaccine adjuvant. However, they are different among various plasmids, motif repeats, species, etc. In the present study, plasmid pcDNA3.1 (+) containing five repetitions of CpG ODN 1670A named
Su H, Liao Z, Yuan G, Su J.
europepmc   +4 more sources

Signatures of dysbiosis in fish microbiomes in the context of aquaculture

Reviews in Aquaculture, Volume 16, Issue 2, Page 706-731, March 2024.
Fish gut microbiome is highly susceptible to salinity changes and antimicrobial treatments, whereas external microbiomes seem to be more susceptible to disease and variations in temperature. Treatments with tetracyclines and florfenicol, as well as bacterial diseases, prompt severe dysbiosis, whereas quinolones, disinfectants and parasitic diseases ...
Raquel Xavier, Ricardo Severino, Sofia M. Silva   +2 more
wiley   +1 more source