Results 1 to 10 of about 756 (154)

Grass Carp Prx 3 Elevates Host Antioxidant Activity and Induces Autophagy to Inhibit Grass Carp Reovirus (GCRV) Replication [PDF]

Antioxidants, 2022
Peroxiredoxins are a family of antioxidant proteins that protect cells from oxidative damage caused by reactive oxygen species (ROS). Herein, the peroxiredoxin 3 gene from grass carp (Ctenopharyngodon idellus), named CiPrx3, was cloned and analyzed.
Pengfei Chu, Libo He, Zuoyan Zhu
exaly   +8 more sources

Oral Vaccination of Grass Carp (Ctenopharyngodon idella) with Baculovirus-Expressed Grass Carp Reovirus (GCRV) Proteins Induces Protective Immunity against GCRV Infection [PDF]

Vaccines, 2021
The grass carp reovirus (GCRV) causes severe hemorrhagic disease with high mortality and leads to serious economic losses in the grass carp (Ctenopharyngodon idella) industry in China.
Changyong Mu, Qiwang Zhong, Yan Meng, Yong Zhou, Nan Jiang, Wenzhi Liu, Yiqun Li, Mingyang Xue, Lingbing Zeng, Vikram N. Vakharia, Yuding Fan   +10 more
doaj   +7 more sources

Recombinant Baculovirus-Produced Grass Carp Reovirus Virus-Like Particles as Vaccine Candidate That Provides Protective Immunity against GCRV Genotype II Infection in Grass Carp [PDF]

Vaccines, 2021
Grass carp reovirus (GCRV) leads to severe hemorrhagic disease in grass carp (Ctenopharyngodon idella) and causes economic losses in grass carp aquaculture.
Jiyuan Yin, Qing Wang, Yingying Li
exaly   +9 more sources

Autophagy Inhibits Grass Carp Reovirus (GCRV) Replication and Protects Ctenopharyngodon idella Kidney (CIK) Cells from Excessive Inflammatory Responses after GCRV Infection [PDF]

Biomolecules, 2020
Autophagy is an essential and highly conserved process in mammals, which is critical to maintaining physiological homeostasis, including cell growth, development, repair, and survival.
Pengfei Chu, Libo He, Rong Huang, Lanjie Liao, Yongming Li, Zuoyan Zhu, Wei Hu, Yaping Wang   +7 more
doaj   +7 more sources

Isolation, Identification, and Genomic Analysis of a Novel Reovirus from Healthy Grass Carp and Its Dynamic Proliferation In Vitro and In Vivo [PDF]

Viruses, 2021
A new grass carp reovirus (GCRV), healthy grass carp reovirus (HGCRV), was isolated from grass carp in 2019. Its complete genome sequence was determined and contained 11 dsRNAs with a total size of 23,688 bp and 57.2 mol% G+C content, encoding 12 ...
Lingbing Zeng, Vikram Vakharia, Yuding Fan   +2 more
exaly   +6 more sources

Cell surface heparan sulfate is an attachment receptor for grass carp reovirus [PDF]

iScience
Summary: Grass carp reovirus (GCRV) causes hemorrhagic disease in grass carp, leading to significant economic losses in China’s aquaculture. However, the cellular receptors responsible for the initiation of GCRV infection remain unclear.
Qian Wang, Hanyue Wang, Xuyang Wang, Cheng Yang, Yongming Li, Lanjie Liao, Zuoyan Zhu, Yaping Wang, Libo He   +8 more
doaj   +4 more sources

The Role of Gut Microbiota in Fish Viral Infection: Mechanisms and Microbiota-Targeted Interventions. [PDF]

Aquac Nutr
Viral diseases represent one of the major threats to the global aquaculture industry. In recent years, the relationship between gut microbiota and viral infections in fish has garnered increasing attention. The gut microbiota contributes critically to fish health and is involved in antiviral defense through immune regulation, secretion of microbial ...
Zhao Q, Shao J, Chen Y, Zhang H.
europepmc   +2 more sources

ATG5 negatively regulates grass carp reovirus-induced immune-inflammatory response by degrading RIG-I and MDA5 [PDF]

Journal of Virology
Grass carp reovirus (GCRV) is the most virulent aquareovirus, inducing hemorrhagic disease that results in significant economic losses for the grass carp aquaculture industry in China.
Pengfei Chu, Yingying Wang, Jian Shen, Yaping Wang, Guobin Chang, Libo He   +5 more
doaj   +2 more sources

Identification and characterization of a novel reovirus strain isolated fromgrass carp (Ctenopharyngodon idella) [PDF]

Virology Journal
Background Grass carp (Ctenopharyngodon idella) hemorrhagic disease (GCHD) is a devastating disease that leads to substantial economic losses in the freshwater aquaculture industry.
Weiguang Kong, Guangyi Ding, Qiushi Zhang, Xinjie Yuan, Yuchao Zhu, Liyuan Ma, Chang Cai, Yong Shi, Qianqian Zhang, Zhen Xu   +9 more
doaj   +2 more sources

Self-assembled nanoparticle vaccine comprised of multiple epitopes provides robust protective immunity against reoviruses in fish model [PDF]

Cell Communication and Signaling
Grass carp reovirus type II (GCRV-II) has inflicted substantial economic damage to aquaculture industry due to highly contagious. To combat epidemic GCRV-II, we rational designed and constructed a multi-epitope nanoparticle vaccine (Pep-Fn) that ...
Fei-Fan Xu, Zhao Zhao, Zhu-Yang Deng, Jia-Lun Tang, Bin Zhu   +4 more
doaj   +2 more sources