Results 11 to 20 of about 933 (174)

Grass Carp Prx 3 Elevates Host Antioxidant Activity and Induces Autophagy to Inhibit Grass Carp Reovirus (GCRV) Replication. [PDF]

Antioxidants (Basel), 2022
Peroxiredoxins are a family of antioxidant proteins that protect cells from oxidative damage caused by reactive oxygen species (ROS). Herein, the peroxiredoxin 3 gene from grass carp (Ctenopharyngodon idellus), named CiPrx3, was cloned and analyzed.
Liang X, Li Y, Chu P, Wang Q, Wang H, Liao L, Yang C, Zhu Z, Wang Y, He L.   +9 more
europepmc   +4 more sources

Oral Vaccination of Grass Carp (Ctenopharyngodon idella) with Baculovirus-Expressed Grass Carp Reovirus (GCRV) Proteins Induces Protective Immunity against GCRV Infection. [PDF]

Vaccines (Basel), 2021
The grass carp reovirus (GCRV) causes severe hemorrhagic disease with high mortality and leads to serious economic losses in the grass carp (Ctenopharyngodon idella) industry in China.
Mu C, Zhong Q, Meng Y, Zhou Y, Jiang N, Liu W, Li Y, Xue M, Zeng L, Vakharia VN, Fan Y.   +10 more
europepmc   +5 more sources

Autophagy Inhibits Grass Carp Reovirus (GCRV) Replication and Protects Ctenopharyngodon idella Kidney (CIK) Cells from Excessive Inflammatory Responses after GCRV Infection. [PDF]

Biomolecules, 2020
Autophagy is an essential and highly conserved process in mammals, which is critical to maintaining physiological homeostasis, including cell growth, development, repair, and survival.
Chu P, He L, Huang R, Liao L, Li Y, Zhu Z, Hu W, Wang Y.   +7 more
europepmc   +5 more sources

Differences in responses of grass carp to different types of grass carp reovirus (GCRV) and the mechanism of hemorrhage revealed by transcriptome sequencing. [PDF]

BMC Genomics, 2017
Background Grass carp is an important farmed fish in China that is affected by serious disease, especially hemorrhagic disease caused by grass carp reovirus (GCRV).
He L, Zhang A, Pei Y, Chu P, Li Y, Huang R, Liao L, Zhu Z, Wang Y.   +8 more
europepmc   +5 more sources

Rapid detection of grass carp reovirus type 1 using RPA-based test strips combined with CRISPR Cas13a system [PDF]

Frontiers in Microbiology, 2023
IntroductionDue to the existence of grass carp reovirus (GCRV), grass carp hemorrhagic disease occurs frequently, and its high pathogenicity and infectivity are great challenges to the aquaculture industry.
Fuxian Zhang, Huaming Li, Liancheng Lei, Mengran Xu, Min Guang, Rongrong Yang, Ruige Chen, Xiaomin Wu, Xinyue Cao   +8 more
core   +3 more sources

The use of an in vitro microneutralization assay to evaluate the potential of recombinant VP5 protein as an antigen for vaccinating against Grass carp reovirus [PDF]

Virology Journal, 2011
Background Grass carp reovirus (GCRV) is the causative pathogen of grass carp hemorrhagic disease, one of the major diseases damaging grass carp Ctenopharyngon idellus breeding industry in China.
Yongxing He, Hongxu Xu, Qian Yang, Dan Xu, Liqun Lu   +4 more
core   +3 more sources

Grass Carp Reovirus (GCRV) Giving Its All to Suppress IFN Production by Countering MAVS Signaling Transduction. [PDF]

Front Immunol, 2020
Viruses typically target host RIG-I-like receptors (RLRs), a group of key factors involved in interferon (IFN) production, to enhance viral infection. To date, though immune evasion methods to contradict IFN production have been characterized for a series of terrestrial viruses, the strategies employed by fish viruses remain unclear.
Lu LF, Li ZC, Zhang C, Zhou XY, Zhou Y, Jiang JY, Chen DD, Li S, Zhang YA.   +8 more
europepmc   +6 more sources

Bid-deficient fish delay grass carp reovirus (GCRV) replication and attenuate GCRV-triggered apoptosis. [PDF]

Oncotarget, 2017
Bid, BH3-interacting domain death agonist, is a pro-apoptotic BH3-only member of Bcl-2 family, playing an important role in apoptosis. In the study, Bid genes from grass carp (Ctenopharyngodon idellus) and rare minnow (Gobiocypris rarus), named CiBid and GrBid, were cloned and analyzed.
He L, Wang H, Luo L, Li Y, Huang R, Liao L, Zhu Z, Wang Y.   +7 more
europepmc   +3 more sources

Germination-Arrest Bacillus subtilis Spores as An Oral Delivery Vehicle of Grass Carp Reovirus (GCRV) Vp7 Antigen Augment Protective Immunity in Grass Carp (Ctenopharyngodon idella). [PDF]

Genes (Basel), 2020
Oral vaccination is a practical method for the active immunization of farmed fish in the matter of animal welfare and handling costs. However, it always shows insufficient protective immunity, mainly due to antigen degradation in the gastrointestinal tract (GIT).
Sun R, Zhang M, Chen H, Wei Y, Ning D.
europepmc   +4 more sources

A Novel Subunit Vaccine Based on Outer Capsid Proteins of Grass Carp Reovirus (GCRV) Provides Protective Immunity against GCRV Infection in Rare Minnow (Gobiocypris rarus). [PDF]

Pathogens, 2020
The grass carp hemorrhagic disease, caused by the grass carp reovirus (GCRV), has resulted in severe economic losses in the aquaculture industry in China. VP4 and VP35 are outer capsid proteins of GCRV and can induce an immune response in the host. Here, three recombinant baculoviruses, AcMNPV-VP35, AcMNPV-VP4, and AcMNPV-VP35-VP4, were generated to ...
Mu C, Vakharia VN, Zhou Y, Jiang N, Liu W, Meng Y, Li Y, Xue M, Zhang J, Zeng L, Zhong Q, Fan Y.   +11 more
europepmc   +5 more sources