Results 11 to 20 of about 270,384 (142)

Insights into the Antiviral Immunity against Grass Carp (Ctenopharyngodon idella) Reovirus (GCRV) in Grass Carp [PDF]

Journal of Immunology Research, 2015
Global fish production from aquaculture has rapidly grown over the past decades, and grass carp shares the largest portion. However, hemorrhagic disease caused by grass carp reovirus (GCRV) results in tremendous loss of grass carp (Ctenopharyngodon ...
Youliang Rao, Jianguo Su
doaj   +3 more sources

Global and Complement Gene-Specific DNA Methylation in Grass Carp after Grass Carp Reovirus (GCRV) Infection [PDF]

International Journal of Molecular Sciences, 2018
Grass carp reovirus (GCRV) causes huge economic loss to the grass carp cultivation industry but the mechanism remains largely unknown. In this study, we investigated the global and complement gene-specific DNA methylation in grass carp after GCRV ...
Libo He, Lv Xiong, Zuoyan Zhu
exaly   +3 more sources

ITGB1b-Deficient Rare Minnows Delay Grass Carp Reovirus (GCRV) Entry and Attenuate GCRV-Triggered Apoptosis [PDF]

International Journal of Molecular Sciences, 2018
Integrin -1 (ITGB1) is a transmembrane protein belonging to the integrin family and it plays an important role in viral entry. In this study, the itgb1b gene of the rare minnow, Gobiocypris rarus, was cloned and analyzed. To investigate the possible role
Libo He, Lv Xiong, Geng Chen
exaly   +3 more sources

Identification, Virulence, and Molecular Characterization of a Recombinant Isolate of Grass Carp Reovirus Genotype I

Viruses, 2021
The hemorrhagic disease of grass carp (HDGC) caused by grass carp reovirus (GCRV) still poses a great threat to the grass carp industry. Isolation and identification of the GCRV genotype I (GCRV-I) has been rarely reported in the past decade.
Weiwei Zeng, Sven M. Bergmannc, Hanxu Dong, Ying Yang, Minglin Wu, Hong Liu, Yanfeng Chen, Hua Li   +7 more
doaj   +2 more sources

Grass Carp Prx 3 Elevates Host Antioxidant Activity and Induces Autophagy to Inhibit Grass Carp Reovirus (GCRV) Replication

Antioxidants, 2022
Peroxiredoxins are a family of antioxidant proteins that protect cells from oxidative damage caused by reactive oxygen species (ROS). Herein, the peroxiredoxin 3 gene from grass carp (Ctenopharyngodon idellus), named CiPrx3, was cloned and analyzed.
Xinyu Liang, Yongming Li, Pengfei Chu, Qian Wang, Hanyue Wang, Lanjie Liao, Cheng Yang, Zuoyan Zhu, Yaping Wang, Libo He   +9 more
doaj   +2 more sources

Type II Grass Carp Reovirus Rapidly Invades Grass Carp (Ctenopharyngodon idella) via Nostril–Olfactory System–Brain Axis, Gill, and Skin on Head

Viruses, 2023
Type II grass carp reovirus (GCRV-II) with high pathogenicity and infectivity causes severe hemorrhagic disease, which leads to extensive death in the grass carp and black carp aquaculture. However, the early invasion portal remains unclear.
Wentao Zhu, Meihua Qiao, Meidi Hu, Xingchen Huo, Yongan Zhang, Jianguo Su   +5 more
doaj   +2 more sources

Inhibitor analysis revealed that clathrin-mediated endocytosis is involed in cellular entry of type III grass carp reovirus

Virology Journal, 2018
Background Grass carp (Ctenopharyngodon idella) hemorrhagic disease is caused by an acute infection with grass carp reovirus (GCRV). The frequent outbreaks of this disease have suppressed development of the grass carp farming industry.
Hao Wang, Weisha Liu, Meng Sun, Dubo Chen, Lingbing Zeng, Liqun Lu, Jing Xie   +6 more
doaj   +2 more sources

GCRV 096 VP6 protein and its impacts on GCRV replication with different genotypes in CIK cells

Aquaculture and Fisheries, 2018
Grass carp reovirus (GCRV) is the causative agent of grass carp hemorrhagic disease, which has detrimental effects on the grass carp aquaculture industry. There are four known genotypes of GCRV and strains of different GCRV genotypes differ greatly.
Xiuying Yan, Lingfang Xiong, Jie Li, Ya Wang, Zaohe Wu, Jichang Jian, Yu Ding   +6 more
doaj   +2 more sources

Molecular Cloning and Characterization of Scavenger Receptor Class B Type 1 in Grass Carp (Ctenopharyngodon idellus) and Its Expression Profile following Grass Carp Reovirus Challenge

Fishes
As a member of the pattern recognition receptor (PRR) class, scavenger receptor class B type 1 (SRB1) plays a key role in innate immunity. Grass carp (Ctenopharyngodon idellus) ranks among the most extensively cultivated freshwater aquaculture species in
Yang Zhang, Jiayuan Shi, Yuntao Lu, Qing Luo, Pengfei Chu, Rong Huang, Kunci Chen, Jian Zhao, Yaping Wang, Mi Ou   +9 more
doaj   +2 more sources

Cloning of Grass Carp Chemokine XC Receptor 1 (XCR1) Gene and Evaluation of Its Expression in Various Organs after GCRV Infection

Fishes, 2022
Interaction between the chemokine receptor XCR1 and its ligand is closely related to the immune function in animals; however, there are only a few reports on role of XCR1 in the immune system of fish. We aimed to analyze the expression of XCR1 in various
Hailuo Yu, Yi Liu, Tiaoyi Xiao, Hongquan Wang, Baohong Xu   +4 more
doaj   +2 more sources