Results 21 to 30 of about 753 (151)

GCRV 096 VP6 protein and its impacts on GCRV replication with different genotypes in CIK cells

Aquaculture and Fisheries, 2018
Grass carp reovirus (GCRV) is the causative agent of grass carp hemorrhagic disease, which has detrimental effects on the grass carp aquaculture industry. There are four known genotypes of GCRV and strains of different GCRV genotypes differ greatly.
Xiuying Yan, Lingfang Xiong, Jie Li, Ya Wang, Zaohe Wu, Jichang Jian, Yu Ding   +6 more
doaj   +2 more sources

Cloning of Grass Carp Chemokine XC Receptor 1 (XCR1) Gene and Evaluation of Its Expression in Various Organs after GCRV Infection

Fishes, 2022
Interaction between the chemokine receptor XCR1 and its ligand is closely related to the immune function in animals; however, there are only a few reports on role of XCR1 in the immune system of fish. We aimed to analyze the expression of XCR1 in various
Hailuo Yu, Yi Liu, Tiaoyi Xiao, Hongquan Wang, Baohong Xu   +4 more
doaj   +2 more sources

Molecular Cloning and Characterization of Scavenger Receptor Class B Type 1 in Grass Carp (Ctenopharyngodon idellus) and Its Expression Profile following Grass Carp Reovirus Challenge

Fishes
As a member of the pattern recognition receptor (PRR) class, scavenger receptor class B type 1 (SRB1) plays a key role in innate immunity. Grass carp (Ctenopharyngodon idellus) ranks among the most extensively cultivated freshwater aquaculture species in
Yang Zhang, Jiayuan Shi, Yuntao Lu, Qing Luo, Pengfei Chu, Rong Huang, Kunci Chen, Jian Zhao, Yaping Wang, Mi Ou   +9 more
doaj   +2 more sources

Type II Grass Carp Reovirus Infects Leukocytes but Not Erythrocytes and Thrombocytes in Grass Carp (Ctenopharyngodon idella)

Viruses, 2021
Grass carp reovirus (GCRV) causes serious losses to the grass carp industry. At present, infectious tissues of GCRV have been studied, but target cells remain unclear. In this study, peripheral blood cells were isolated, cultured, and infected with GCRV.
Ling Yang, Jianguo Su
doaj   +2 more sources

Protective roles of grass carp Ctenopharyngodon idella Mx isoforms against grass carp reovirus.

PLoS ONE, 2012
BackgroundMyxovirus resistance (Mx) proteins are crucial effectors of the innate antiviral response against a wide range of viruses, mediated by the type I interferon (IFN-I) signaling pathway.
Limin Peng, Chunrong Yang, Jianguo Su, Jianguo Su   +3 more
doaj   +2 more sources

Grass carp catalase inhibits GCRV replication through ROS scavenging-mediated immune suppression and autophagy [PDF]

Virulence
Catalase (CAT) is a key antioxidant enzyme that eliminates reactive oxygen species (ROS), thereby protecting organisms from oxidative stress and maintaining cellular homeostasis.
Xuyang Wang, Xiaowen Zou, Linlin Liu, Xinyu Liang, Hanyue Wang, Cheng Yang, Yongming Li, Lanjie Liao, Zuoyan Zhu, Yaping Wang, Jingjing Zhao, Libo He   +11 more
doaj   +2 more sources

Rapid detection of grass carp reovirus type 1 using RPA-based test strips combined with CRISPR Cas13a system [PDF]

Frontiers in Microbiology, 2023
IntroductionDue to the existence of grass carp reovirus (GCRV), grass carp hemorrhagic disease occurs frequently, and its high pathogenicity and infectivity are great challenges to the aquaculture industry.
Huaming Li, Xinyue Cao, Ruige Chen, Min Guang, Mengran Xu, Xiaomin Wu, Rongrong Yang, Liancheng Lei, Fuxian Zhang   +8 more
doaj   +2 more sources

Sialic acid serves as a functional receptor for grass carp reovirus. [PDF]

PLoS Pathogens
Grass carp reovirus (GCRV) causes hemorrhagic disease and substantial economic losses in the aquaculture of grass carp (Ctenopharyngodon idella), a commercially important fish species in China.
Qian Wang, Zichao Peng, Bin Gui, Yongming Li, Lanjie Liao, Zuoyan Zhu, Yaping Wang, Libo He   +7 more
doaj   +2 more sources

GCRV-II Triggers B and T Lymphocyte Apoptosis via Mitochondrial ROS Pathway [PDF]

Viruses
Grass carp reovirus (GCRV), particularly the highly prevalent genotype II (GCRV-II), is known to infect peripheral blood leukocytes (PBLs) of grass carp. However, it is unclear whether GCRV-II can induce apoptosis in bystander lymphocytes within infected
Jie Wang, Wen-Jing Dong, Chang-Song Wu, Tian-Tian Tian, Xu-Jie Zhang, Yong-An Zhang   +5 more
doaj   +2 more sources

Grass carp reovirus VP4 manipulates TOLLIP to degrade STING for inhibition of IFN production [PDF]

Journal of Virology
Although fish possess an effective interferon (IFN) system to defend against viral infection, grass carp reovirus (GCRV) still causes epidemic hemorrhagic disease and tremendous economic loss in grass carp.
Yang-Yang Wang, Xue-Li Wang, Zhuo-Cong Li, Can Zhang, Xiao Xu, Bao-Jie Cui, Meng-Ze Tian, Chu-Jing Zhou, Na Xu, Yue Wu, Xiao-Li Yang, Dan-Dan Chen, Long-Feng Lu, Shun Li   +13 more
doaj   +2 more sources