Results 31 to 40 of about 270,384 (142)

Characterization of grass carp FosB, Fosl2, JunD transcription factors in response to GCRV infection

Aquaculture and Fisheries, 2022
Activating protein-1 (AP-1) composed of Jun and Fos family proteins, which are frequently activated by pathogens to induce cellular inflammation and immune responses. In this study, by using RNA sequencing (RNA-seq) technology, we found that FosB, Fosl2,
Fei Yu, Wanjuan Li, Longlong Wang, Shunzheng Que, Liqun Lu   +4 more
doaj   +1 more source

Grass Carp Reovirus Induces Formation of Lipid Droplets as Sites for Its Replication and Assembly

mBio, 2022
Grass carp is an important commercial fish in China that is plagued by various diseases, especially the hemorrhagic disease induced by grass carp reovirus (GCRV).
Libo He, Qian Wang, Xinyu Liang, Hanyue Wang, Pengfei Chu, Cheng Yang, Yongming Li, Lanjie Liao, Zuoyan Zhu, Yaping Wang   +9 more
doaj   +1 more source

Piscine Vitamin D Receptors Vdra/Vdrb in the Absence of Vitamin D Are Utilized by Grass Carp Reovirus for Promoting Viral Replication

Microbiology Spectrum, 2023
The vitamin D receptor (VDR) plays a pivotal role in the biological actions of vitamin D (VitD). However, little is known about the functions of VDR in the production of viral inclusion bodies (VIBs). Using a representative strain of grass carp reovirus (
Yun Jie Song, Jie Zhang, Jun Xiao, Hao Feng, Zhen Xu, Pin Nie, Ming Xian Chang   +6 more
doaj   +1 more source

Grass carp SERPINA1 inhibits GCRV infection through degrading CF2

Frontiers in Immunology, 2022
SERPINA1, a member of the serine protease inhibitor family, plays a role in viral infection and inflammation by regulating the activities of serine and cysteine proteases.
Yangyang Li, Yangyang Li, Liangming Chen, Liangming Chen, Rong Huang, Yangyu Li, Yangyu Li, Cheng Yang, Bin Gui, Bin Gui, Yongming Li, Lanjie Liao, Zuoyan Zhu, Yaping Wang, Yaping Wang   +14 more
doaj   +1 more source

Advances in research of biological functions of Isthmin‐1

Journal of Cell Communication and Signaling, Volume 17, Issue 3, Page 507-521, September 2023., 2023
Graphical abstract The main biological functions of ISM1. Current studies on the biological functions of ISM1 focus on growth and development, metabolism, and anticancer treatment. During embryonic development, ISM1 is dynamically expressed in the zebrafish, African clawed frog, chick, mouse, and human, is associated with craniofacial malformations ...
Li Menghuan, Yang Yang, Ma Qianhe, Zhang Na, Cao Shicheng, Chang Bo, Y. I. XueJie   +6 more
wiley   +1 more source

Pro-inflammatory regulatory mechanism of C5a/C5aR pathway in GCRV-infected grass carp (Ctenopharyngodon idella)

Aquaculture Reports, 2023
Death of grass carp (Ctenopharyngodon idella) caused by grass carp reovirus (GCRV) infection severely restricts the development of the grass carp industry.
Baohong Xu, Hang Su, Changjun Chen, Qiaolin Liu, Tiaoyi Xiao, Yi Liu, Zhao Lv, Hongquan Wang, Zheyu Wen   +8 more
doaj   +1 more source

Single‐cell transcriptome profiling reveals diverse immune cell populations and their responses to viral infection in the spleen of zebrafish

The FASEB Journal, Volume 37, Issue 6, June 2023., 2023
A comprehensive atlas of immune cell types in zebrafish was generated on the basis of single‐cell transcriptome profiling. The splenic leukocytes were collected from adult zebrafish that were administered with mock phosphate‐buffered saline, infected with spring viremia of carp virus (SVCV), and vaccinated with inactivated SVCV plus infected with ...
Chong‐Bin Hu, Jie Wang, Yun Hong, Hao Li, Dong‐Dong Fan, Ai‐Fu Lin, Li‐Xin Xiang, Jian‐Zhong Shao   +7 more
wiley   +1 more source

Fish disease prevention via microbial dysbiosis‐associated biomarkers in aquaculture

Reviews in Aquaculture, Volume 15, Issue 2, Page 579-594, March 2023., 2023
Abstract Infectious diseases are a major burden in aquaculture, and represent a significant yield‐limiting factor in production that is costly to manage as well as a potential vector for zoonoses. Over the past decades, a range of new diseases have emerged, alongside increased levels of antibiotic resistance, thus heightening the need for improved ...
Julia Mougin, Alyssa Joyce
wiley   +1 more source

Characterization, Expression, and Ligand Binding of LGP2 and MDA5 in Largemouth Black Bass Micropterus salmoides (Lacepède, 1802)

Aquaculture Research, Volume 2023, Issue 1, 2023., 2023
Melanoma differentiation‐associated gene 5 (MDA5) and the laboratory of genetics and physiology 2 (LGP2) are family members of retinoic acid‐inducible gene I (RIG‐I)‐like receptors (RLRs), which play important roles in the immune response against pathogens invasion.
Xiangyu Pi, Yang Xu, Yiwen Cao, Qihuan Zhang, Zisheng Wang, Zhitao Qi, Mohamed Abdelsalam   +6 more
wiley   +1 more source

Rapid detection of grass carp reovirus type 1 using RPA-based test strips combined with CRISPR Cas13a system

Frontiers in Microbiology, 2023
IntroductionDue to the existence of grass carp reovirus (GCRV), grass carp hemorrhagic disease occurs frequently, and its high pathogenicity and infectivity are great challenges to the aquaculture industry.
Huaming Li, Xinyue Cao, Ruige Chen, Min Guang, Mengran Xu, Xiaomin Wu, Rongrong Yang, Liancheng Lei, Fuxian Zhang   +8 more
doaj   +1 more source