Results 51 to 60 of about 270,384 (142)

Insights on the Multifunctional Activities of Magnolol

BioMed Research International, Volume 2019, Issue 1, 2019., 2019
Over years, various biological constituents are isolated from Traditional Chinese Medicine and confirmed to show multifunctional activities. Magnolol, a hydroxylated biphenyl natural compound isolated from Magnolia officinalis, has been extensively documented and shows a range of biological activities.
Jianhong Zhang, Zhixi Chen, Xianhua Huang, Weimei Shi, Rui Zhang, Meiling Chen, Hao Huang, Longhuo Wu, Antoni Camins   +8 more
wiley   +1 more source

Complete genome sequence and comparative analysis of grass carp reovirus strain 109 (GCReV-109) with other grass carp reovirus strains reveals no significant correlation with regional distribution

, 2014
A new grass carp reovirus strain, tentatively named GCReV-109, was isolated in Hubei, China, and its complete genome sequence was determined. The genome contained 11 double-stranded RNA segments (S1-S11) covering 24,620 base pairs.
Pei, Chao, Ke, Fei, Zhang, Qi-Ya, Chen, Zhong-Yuan   +3 more
core   +1 more source

An Oral Microencapsulated Vaccine Loaded by Sodium Alginate Effectively Enhances Protection Against GCRV Infection in Grass Carp (Ctenopharyngodon idella)

Frontiers in Immunology, 2022
Grass carp reovirus (GCRV) is highly infectious and lethal to grass carp, causing huge economic losses to the aquaculture industry annually. Currently, vaccination is the most effective method against viral infections.
Chuang Xu, Chuang Xu, Chuang Xu, Meihua Qiao, Xingchen Huo, Zhiwei Liao, Jianguo Su, Jianguo Su, Jianguo Su   +8 more
doaj   +1 more source

Isolation and analysis of a novel grass carp toll-like receptor 4 (tlr4) gene cluster involved in the response to grass carp reovirus

, 2012
The mammalian response to lipopolysaccharide (LPS) is mainly mediated by Toll-Like Receptor 4 (TLR4). Fish and mammalian TLR4 vary; fish TLR4 ligands are unknown. Isolation of fish tlr4 genes is difficult due to their complex genomic structure.
Wang, YP (reprint author), Chinese Acad Sci, Inst Hydrobiol, Ctr Fish Biol & Fishery Biotechnol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Hubei, Peoples R China., Huang, Rong, Wang, Yaping, Dong, Feng, Zhu, Zuoyan, Liao, Lanjie, Jang, Songhun   +6 more
core   +1 more source

A Review of Intra‐ and Extracellular Antigen Delivery Systems for Virus Vaccines of Finfish

Journal of Immunology Research, Volume 2015, Issue 1, 2015., 2015
Vaccine efficacy in aquaculture has for a long time depended on evaluating relative percent survival and antibody responses after vaccination. However, current advances in vaccine immunology show that the route in which antigens are delivered into cells is deterministic of the type of adaptive immune response evoked by vaccination.
Hetron Mweemba Munang’andu, Øystein Evensen, Kurt Blaser   +2 more
wiley   +1 more source

Comparative study of the immunoprotective effect of two grass carp-sourced Bacillus subtilis spore-based vaccines against grass carp reovirus [PDF]

, 2019
Grass carp reovirus II (GCRV II) causes severe haemorrhagic disease with high mortality in grass carp, Cyenopharyngodon idellus. Vaccination is a very effective method in conferring protection against GCRV.
Zhou, Yuan-Yuan, Zhang, Xiang-Yang, Zhang, Yong-An, Guo, Xia, Chen, Dan-Dan, Yao, Yuan-Yuan, Cui, Zheng-Wei   +6 more
core   +1 more source

Novel Duck Orthoreovirus Induces Ferroptosis in HD11 Cells by Hijacking Cellular Iron Metabolism and Promoting Iron Accumulation

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Novel duck orthoreovirus (NDRV) infection induces severe splenic necrosis in ducks, resulting in a cascade of detrimental consequences, including immunosuppression, secondary infections, and diminished vaccine efficacy. Avian orthoreovirus (ARV) exhibits high tropism for macrophages, with splenic macrophages being identified as the primary target cells
Hongzhi Wang, Di Lei, Chenchen Jiang, Boyi Xu, Yi Tang, Rendong Fang, Zongfu Wu   +6 more
wiley   +1 more source

Antigenic analysis of grass carp reovirus using single-chain variable fragment antibody against IgM from Ctenopharyngodon idella

, 2013
Grass carp (Ctenopharyngodon idella) is an important species of freshwater aquaculture fish in China. However, grass carp reovirus (GCRV) can cause fatal hemorrhagic disease in yearling populations.
Sun XiaoYun, Liao LanJie, Luo ShaoXiang, Fang Qin, Dai HePing, Wang YaPing, Zhang XiaoHua, Fang, Q (reprint author), Chinese Acad Sci, Wuhan Inst Virol, State Key Lab Virol, Wuhan 430071, Peoples R China., Chen CongLin, Li ZhouQuan, Guo QionLin   +10 more
core   +1 more source

Structural and functional analysis of the small GTPase ARF1 reveals a pivotal role of its GTP-binding domain in controlling of the generation of viral inclusion bodies and replication of grass carp reovirus

Frontiers in Immunology, 2022
Grass carp reovirus (GCRV) is the most pathogenic double-stranded (ds) RNA virus among the isolated aquareoviruses. The molecular mechanisms by which GCRV utilizes host factors to generate its infectious compartments beneficial for viral replication and ...
Jie Zhang, Pengwei Li, Pengwei Li, Riye Lu, Songying Ouyang, Ming Xian Chang, Ming Xian Chang, Ming Xian Chang   +7 more
doaj   +1 more source

RNA‐Based Biopesticides: Pioneering Precision Solutions for Sustainable Aquaculture in China

Animal Research and One Health, Volume 3, Issue 2, Page 165-176, May 2025.
The Chinese dragon represents RNA biopesticides, which effectively counteract bacterial, viral, and parasitic threats, safeguarding aquatic life. This method is precise, focusing solely on harmful agents and sparing beneficial aquaculture species. Its innovative nature protects aquatic environments while reducing ecological footprint.
Yiran Huang, Yingmin Dai, Zhuotong Huang, Mengqi Zhang, Lijun Xiu, Xianhui Zhang, Youyu Zhang, Lixing Huang   +7 more
wiley   +1 more source