Results 51 to 60 of about 933 (174)

Grass Carp Reovirus VP56 Allies VP4, Recruits, Blocks, and Degrades RIG-I to More Effectively Attenuate IFN Responses and Facilitate Viral Evasion

open access: yesMicrobiology Spectrum, 2021
Grass carp reovirus (GCRV), the most virulent aquareovirus, causes epidemic hemorrhagic disease and tremendous economic loss in freshwater aquaculture industry.
Hang Su   +4 more
doaj   +1 more source

Phylogenetic analysis of newly isolated grass carp reovirus [PDF]

open access: yes, 2014
Grass carp reovirus (GCRV) is a causative agent of haemorrhagic disease in grass carp that drastically affects grass carp aquaculture. Here we report a novel GCRV isolate isolated from sick grass carp that induces obvious cytopathic effect in CIK cells ...
Ji-chang Jian   +4 more
core   +1 more source

Cytosolic sensors for pathogenic viral and bacterial nucleic acids in fish [PDF]

open access: yes, 2020
Not AvailableAs per ...
Gouranga Biswas   +6 more
core   +1 more source

Antibodies against outer-capsid proteins of grass carp reovirus expressed in E. coli are capable of neutralizing viral infectivity [PDF]

open access: yes, 2011
Background Grass carp reovirus (GCRV), which causes severe infectious outbreaks of hemorrhagic disease in aquatic animals, is a highly pathogenic agent in the Aquareovirus genus of family Reoviridae.
Ling Shao, Xiaoyun Sun, Qin Fang
core   +2 more sources

Characterization of grass carp reovirus minor core protein VP4 [PDF]

open access: yes, 2012
Background Grass Carp Reovirus (GCRV), a tentative member in the genus Aquareovirus of family Reoviridae, contains eleven segmented (double-stranded RNA) dsRNA genome which encodes 12 proteins.
Fang, Qin   +4 more
core   +3 more sources

Molecular cloning and preliminary functional analysis of six RING-between-ring (RBR) genes in grass carp (Ctenopharyngodon idellus) [PDF]

open access: yes, 2019
Ubiquitination is a post-translational modification of proteins that is widely present in eukaryotic cells. There is increasing evidence that ubiquitinated proteins play crucial roles in the immune response process.
He, Libo   +9 more
core   +1 more source

GCRV-II Triggers B and T Lymphocyte Apoptosis via Mitochondrial ROS Pathway. [PDF]

open access: yesViruses
Grass carp reovirus (GCRV), particularly the highly prevalent genotype II (GCRV-II), is known to infect peripheral blood leukocytes (PBLs) of grass carp. However, it is unclear whether GCRV-II can induce apoptosis in bystander lymphocytes within infected
Wang J   +5 more
europepmc   +2 more sources

Grass carp reovirus VP4 manipulates TOLLIP to degrade STING for inhibition of IFN production. [PDF]

open access: yesJ Virol
Although fish possess an effective interferon (IFN) system to defend against viral infection, grass carp reovirus (GCRV) still causes epidemic hemorrhagic disease and tremendous economic loss in grass carp.
Wang Y-Y   +13 more
europepmc   +2 more sources

Molecular and antigenic characterization of Piscine orthoreovirus (PRV) from rainbow trout (Oncorhynchus mykiss) [PDF]

open access: yes, 2018
Piscine orthoreovirus (PRV-1) causes heart and skeletal muscle inflammation (HSMI) in farmed Atlantic salmon (Salmo salar). Recently, a novel PRV (formerly PRV-Om, here called PRV-3), was found in rainbow trout (Oncorhynchus mykiss) with HSMI-like ...
Cuenca, Argelia   +9 more
core   +2 more sources

Genome-wide DNA methylation reveals potential epigenetic mechanism of age-dependent viral susceptibility in grass carp

open access: yesImmunity & Ageing, 2022
Background Grass carp are an important farmed fish in China that are infected by many pathogens, especially grass carp reovirus (GCRV). Notably, grass carp showed age-dependent susceptibility to GCRV; that is, grass carp not older than one year were ...
Libo He   +7 more
doaj   +1 more source

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