Results 51 to 60 of about 753 (151)

Grass Carp Reovirus VP56 Allies VP4, Recruits, Blocks, and Degrades RIG-I to More Effectively Attenuate IFN Responses and Facilitate Viral Evasion

Microbiology Spectrum, 2021
Grass carp reovirus (GCRV), the most virulent aquareovirus, causes epidemic hemorrhagic disease and tremendous economic loss in freshwater aquaculture industry.
Hang Su, Zhiwei Liao, Chunrong Yang, Yongan Zhang, Jianguo Su   +4 more
doaj   +1 more source

Fish type I and type II interferons: composition, receptor usage, production and function

Reviews in Aquaculture, Volume 12, Issue 2, Page 773-804, May 2020., 2020
Abstract Interferons (IFNs) have been reported in vertebrates from fish to mammals. To date, two types of IFNs, i.e. type I and type II IFNs have been reported in a range of fish species in aquaculture. In fish, type I IFNs are clarified into group I and group II, with two cysteines and four cysteines, and further into subgroups a, d, e, h, and b, c, f,
Zhen Gan, Shan Nan Chen, Bei Huang, Jun Zou, Pin Nie   +4 more
wiley   +1 more source

Genome-wide DNA methylation reveals potential epigenetic mechanism of age-dependent viral susceptibility in grass carp

Immunity & Ageing, 2022
Background Grass carp are an important farmed fish in China that are infected by many pathogens, especially grass carp reovirus (GCRV). Notably, grass carp showed age-dependent susceptibility to GCRV; that is, grass carp not older than one year were ...
Libo He, Xinyu Liang, Qian Wang, Cheng Yang, Yongming Li, Lanjie Liao, Zuoyan Zhu, Yaping Wang   +7 more
doaj   +1 more source

Oral PLGA-based DNA vaccines using interferons as adjuvants remarkably promote the immune protection of grass carp (Ctenopharyngodon idella) against GCRV infection

Water Biology and Security, 2023
Grass carp hemorrhagic disease caused by grass carp reovirus (GCRV) results in significant economic losses to the global grass carp aquaculture industry. Oral vaccination is an ideal choice for disease precaution in aquaculture. However, oral vaccine can
Chaolin Jiang, Xingchen Huo, Lingjie Tang, Meidi Hu, Chunrong Yang, Daji Luo, Jianguo Su   +6 more
doaj   +1 more source

An Aquareovirus Exploits Membrane-Anchored HSP70 To Promote Viral Entry

Microbiology Spectrum, 2023
Temperature dependency of viral diseases in ectotherms has been an important scientific issue for decades, while the molecular mechanism behind this phenomenon remains largely mysterious. In this study, deploying infection with grass carp reovirus (GCRV),
Guoli Hou, Qiushi Zhang, Chun Li, Geye Ding, Lingling Hu, Xiaoying Chen, Zhao Lv, Yuding Fan, Jun Zou, Tiaoyi Xiao, Yong-An Zhang, Junhua Li   +11 more
doaj   +1 more source

Insights on the Multifunctional Activities of Magnolol

BioMed Research International, Volume 2019, Issue 1, 2019., 2019
Over years, various biological constituents are isolated from Traditional Chinese Medicine and confirmed to show multifunctional activities. Magnolol, a hydroxylated biphenyl natural compound isolated from Magnolia officinalis, has been extensively documented and shows a range of biological activities.
Jianhong Zhang, Zhixi Chen, Xianhua Huang, Weimei Shi, Rui Zhang, Meiling Chen, Hao Huang, Longhuo Wu, Antoni Camins   +8 more
wiley   +1 more source

Oral Administration of Bacillus subtilis Subunit Vaccine Significantly Enhances the Immune Protection of Grass Carp against GCRV-II Infection

Viruses, 2021
Grass carp reovirus (GCRV) is a severe virus that causes great losses to grass carp culture every year, and GCRV-II is the current popular and fatal strain. VP56, fibrin on the outer surface of GCRV-II, mediates cell attachment. In this study, we firstly
Yang Gao, Xingchen Huo, Zhensheng Wang, Gailing Yuan, Xiaoling Liu, Taoshan Ai, Jianguo Su   +6 more
doaj   +1 more source

Complete genome sequence and comparative analysis of grass carp reovirus strain 109 (GCReV-109) with other grass carp reovirus strains reveals no significant correlation with regional distribution

, 2014
A new grass carp reovirus strain, tentatively named GCReV-109, was isolated in Hubei, China, and its complete genome sequence was determined. The genome contained 11 double-stranded RNA segments (S1-S11) covering 24,620 base pairs.
Pei, Chao, Ke, Fei, Zhang, Qi-Ya, Chen, Zhong-Yuan   +3 more
core   +1 more source

An Oral Microencapsulated Vaccine Loaded by Sodium Alginate Effectively Enhances Protection Against GCRV Infection in Grass Carp (Ctenopharyngodon idella)

Frontiers in Immunology, 2022
Grass carp reovirus (GCRV) is highly infectious and lethal to grass carp, causing huge economic losses to the aquaculture industry annually. Currently, vaccination is the most effective method against viral infections.
Chuang Xu, Chuang Xu, Chuang Xu, Meihua Qiao, Xingchen Huo, Zhiwei Liao, Jianguo Su, Jianguo Su, Jianguo Su   +8 more
doaj   +1 more source

A Review of Intra‐ and Extracellular Antigen Delivery Systems for Virus Vaccines of Finfish

Journal of Immunology Research, Volume 2015, Issue 1, 2015., 2015
Vaccine efficacy in aquaculture has for a long time depended on evaluating relative percent survival and antibody responses after vaccination. However, current advances in vaccine immunology show that the route in which antigens are delivered into cells is deterministic of the type of adaptive immune response evoked by vaccination.
Hetron Mweemba Munang’andu, Øystein Evensen, Kurt Blaser   +2 more
wiley   +1 more source