Results 61 to 70 of about 753 (151)

Isolation and analysis of a novel grass carp toll-like receptor 4 (tlr4) gene cluster involved in the response to grass carp reovirus

, 2012
The mammalian response to lipopolysaccharide (LPS) is mainly mediated by Toll-Like Receptor 4 (TLR4). Fish and mammalian TLR4 vary; fish TLR4 ligands are unknown. Isolation of fish tlr4 genes is difficult due to their complex genomic structure.
Wang, YP (reprint author), Chinese Acad Sci, Inst Hydrobiol, Ctr Fish Biol & Fishery Biotechnol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Hubei, Peoples R China., Huang, Rong, Wang, Yaping, Dong, Feng, Zhu, Zuoyan, Liao, Lanjie, Jang, Songhun   +6 more
core   +1 more source

Novel Duck Orthoreovirus Induces Ferroptosis in HD11 Cells by Hijacking Cellular Iron Metabolism and Promoting Iron Accumulation

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Novel duck orthoreovirus (NDRV) infection induces severe splenic necrosis in ducks, resulting in a cascade of detrimental consequences, including immunosuppression, secondary infections, and diminished vaccine efficacy. Avian orthoreovirus (ARV) exhibits high tropism for macrophages, with splenic macrophages being identified as the primary target cells
Hongzhi Wang, Di Lei, Chenchen Jiang, Boyi Xu, Yi Tang, Rendong Fang, Zongfu Wu   +6 more
wiley   +1 more source

RNA‐Based Biopesticides: Pioneering Precision Solutions for Sustainable Aquaculture in China

Animal Research and One Health, Volume 3, Issue 2, Page 165-176, May 2025.
The Chinese dragon represents RNA biopesticides, which effectively counteract bacterial, viral, and parasitic threats, safeguarding aquatic life. This method is precise, focusing solely on harmful agents and sparing beneficial aquaculture species. Its innovative nature protects aquatic environments while reducing ecological footprint.
Yiran Huang, Yingmin Dai, Zhuotong Huang, Mengqi Zhang, Lijun Xiu, Xianhui Zhang, Youyu Zhang, Lixing Huang   +7 more
wiley   +1 more source

Antigenic analysis of grass carp reovirus using single-chain variable fragment antibody against IgM from Ctenopharyngodon idella

, 2013
Grass carp (Ctenopharyngodon idella) is an important species of freshwater aquaculture fish in China. However, grass carp reovirus (GCRV) can cause fatal hemorrhagic disease in yearling populations.
Sun XiaoYun, Liao LanJie, Luo ShaoXiang, Fang Qin, Dai HePing, Wang YaPing, Zhang XiaoHua, Fang, Q (reprint author), Chinese Acad Sci, Wuhan Inst Virol, State Key Lab Virol, Wuhan 430071, Peoples R China., Chen CongLin, Li ZhouQuan, Guo QionLin   +10 more
core   +1 more source

Structural and functional analysis of the small GTPase ARF1 reveals a pivotal role of its GTP-binding domain in controlling of the generation of viral inclusion bodies and replication of grass carp reovirus

Frontiers in Immunology, 2022
Grass carp reovirus (GCRV) is the most pathogenic double-stranded (ds) RNA virus among the isolated aquareoviruses. The molecular mechanisms by which GCRV utilizes host factors to generate its infectious compartments beneficial for viral replication and ...
Jie Zhang, Pengwei Li, Pengwei Li, Riye Lu, Songying Ouyang, Ming Xian Chang, Ming Xian Chang, Ming Xian Chang   +7 more
doaj   +1 more source

Fish Genomics and Its Application in Disease‐Resistance Breeding

Reviews in Aquaculture, Volume 17, Issue 1, January 2025.
ABSTRACT Global aquaculture production has been rising for several decades, with up to 76% of the total production from fish. However, the problem of fish diseases is becoming more and more prominent in today's context of pursuing sustainable aquaculture.
Yu Huang, Zeyu Li, Mengcheng Li, Xinhui Zhang, Qiong Shi, Zhen Xu   +5 more
wiley   +1 more source

Genome Manipulation Advances in Selected Aquaculture Organisms

Reviews in Aquaculture, Volume 17, Issue 1, January 2025.
ABSTRACT With the rising global demand for seafood and the challenges posed by overfishing and climate change, the aquaculture sector has become increasingly important in providing high‐quality protein for human consumption. Although traditional selection breeding programs have made great strides in genetic improvement of aquaculture species over the ...
Jinhai Wang, Yu Cheng, Baofeng Su, Rex A. Dunham   +3 more
wiley   +1 more source

Large-scale SNP screenings identify markers linked with GCRV resistant traits through transcriptomes of individuals and cell lines in Ctenopharyngodon idella

Scientific Reports, 2017
Grass carp (Ctenopharyngodon idella) is an important economic species in freshwater aquaculture and its industry has been confined due to variety degeneration and frequent diseases. Marker-assisted selection is a feasible method for selective breeding of
Zhiwei Liao, Quanyuan Wan, Xueying Shang, Jianguo Su   +3 more
doaj   +1 more source

Analysis of GCRV Pathogenesis and Therapeutic Measures Through Proteomic and Metabolomic Investigations in GCRV-Infected Tissues of Grass Carp (Ctenopharyngodon idella). [PDF]

Int J Mol Sci
Hemorrhagic disease caused by grass carp reovirus (GCRV) infection is a major problem affecting the grass carp aquaculture industry. Therefore, inhibiting the spread of GCRV infection is of great economic significance.
Xie J, Jia Z, Li Y, Liao L, Zhu Z, Wang Y, Huang R.   +6 more
europepmc   +2 more sources

Carbon‐Based Nanomaterials for Antiviral Applications

Advanced Functional Materials, Volume 34, Issue 38, September 18, 2024.
Carbon‐based nanomaterials (CBNs), including fullerenes, carbon dots, graphene, and their derivatives, show promise as antiviral tools in the antimicrobial resistance era. They exhibit broad‐spectrum antiviral activity with a low risk of resistance development. CBNs also enhance efficacy under light exposure and support antiviral immune responses. CBNs
Ángel Serrano‐Aroca, Kazuo Takayama, Yogendra Kumar Mishra, Cesar de la Fuente‐Nunez   +3 more
wiley   +1 more source