Results 61 to 70 of about 933 (174)

Oncolytic reovirus as a combined antiviral and anti-tumour agent for the treatment of liver cancer [PDF]

, 2018
Objective: Oncolytic viruses (OVs) represent promising, proinflammatory cancer treatments. Here, we explored whether OV-induced innate immune responses could simultaneously inhibit HCV while suppressing hepatocellular carcinoma (HCC).
Abigail Bloy, Adam Peckham-Cooper, Adel Samson, Alan Melcher, Elizabeth Appleton, Fiona Errington-Mais, Franssen, Gerard Nuovo, Giles Toogood, Hagan, Hsu, Jebar, Karen Scott, Kevin Harrington, Lao, Matthew Coffey, Matthew J Bentham, Peter Selby, Rajiv Dave, Reig, Richard Vile, Robert A Adair, Seishi Nagamori, Stephen Griffin, Utsunomiya, Yamashita   +25 more
core   +1 more source

Oral vaccination of fish against vibriosis using spore-display technology [PDF]

, 2022
Publisher Copyright: Copyright © 2022 Gonçalves, Santos, Coutinho, Pedrosa, Curado, Machado, Costas, Bonneville, Serrano, Carvalho, Díaz-Rosales, Oliva-Teles, Couto and Serra.Oral vaccines are highly demanded by the aquaculture sector, to allow mass ...
Bonneville, Lourenço, Carvalho, António Paulo, Costas, Benjamin, Coutinho, Filipe, Couto, Ana, Curado, Maria, Díaz-Rosales, Patricia, Gonçalves, Gabriela, Machado, Marina, Oliva-Teles, Aires, Pedrosa, Neide, Santos, Rafaela A., Serra, Cláudia R., Serrano, Mónica   +13 more
core   +3 more sources

Nanodelivery Systems as New Tools for Immunostimulant or Vaccine Administration : Targeting the Fish Immune System [PDF]

, 2015
Fish disease treatments have progressed significantly over the last few years and have moved from the massive use of antibiotics to the development of vaccines mainly based on inactivated bacteria.
Ji, Jie, Roher Armentia, Nerea, Ruyra Ripoll, Àngels, Torrealba, Debora   +3 more
core   +3 more sources

The Bacterial Spore as a Mucosal Vaccine Delivery System [PDF]

, 2023
: The development of efficient mucosal vaccines is strongly dependent on the use of appropriate vectors. Various biological systems or synthetic nanoparticles have been proposed to display and deliver antigens to mucosal surfaces.
Baccigalupi, Loredana, Donadio, Giuliana, Isticato, Rachele, Ricca, Ezio, Saggese, Anella   +4 more
core   +1 more source

Oral PLGA-based DNA vaccines using interferons as adjuvants remarkably promote the immune protection of grass carp (Ctenopharyngodon idella) against GCRV infection

Water Biology and Security, 2023
Grass carp hemorrhagic disease caused by grass carp reovirus (GCRV) results in significant economic losses to the global grass carp aquaculture industry. Oral vaccination is an ideal choice for disease precaution in aquaculture. However, oral vaccine can
Chaolin Jiang, Xingchen Huo, Lingjie Tang, Meidi Hu, Chunrong Yang, Daji Luo, Jianguo Su   +6 more
doaj   +1 more source

Insights on the Multifunctional Activities of Magnolol

BioMed Research International, Volume 2019, Issue 1, 2019., 2019
Over years, various biological constituents are isolated from Traditional Chinese Medicine and confirmed to show multifunctional activities. Magnolol, a hydroxylated biphenyl natural compound isolated from Magnolia officinalis, has been extensively documented and shows a range of biological activities.
Jianhong Zhang, Zhixi Chen, Xianhua Huang, Weimei Shi, Rui Zhang, Meiling Chen, Hao Huang, Longhuo Wu, Antoni Camins   +8 more
wiley   +1 more source

Molecular Cloning and Characterization of Scavenger Receptor Class B Type 1 in Grass Carp (Ctenopharyngodon idellus) and Its Expression Profile following Grass Carp Reovirus Challenge

Fishes
As a member of the pattern recognition receptor (PRR) class, scavenger receptor class B type 1 (SRB1) plays a key role in innate immunity. Grass carp (Ctenopharyngodon idellus) ranks among the most extensively cultivated freshwater aquaculture species in
Yang Zhang, Jiayuan Shi, Yuntao Lu, Qing Luo, Pengfei Chu, Rong Huang, Kunci Chen, Jian Zhao, Yaping Wang, Mi Ou   +9 more
doaj   +1 more source

An Aquareovirus Exploits Membrane-Anchored HSP70 To Promote Viral Entry

Microbiology Spectrum, 2023
Temperature dependency of viral diseases in ectotherms has been an important scientific issue for decades, while the molecular mechanism behind this phenomenon remains largely mysterious. In this study, deploying infection with grass carp reovirus (GCRV),
Guoli Hou, Qiushi Zhang, Chun Li, Geye Ding, Lingling Hu, Xiaoying Chen, Zhao Lv, Yuding Fan, Jun Zou, Tiaoyi Xiao, Yong-An Zhang, Junhua Li   +11 more
doaj   +1 more source

Oral Administration of Bacillus subtilis Subunit Vaccine Significantly Enhances the Immune Protection of Grass Carp against GCRV-II Infection

Viruses, 2021
Grass carp reovirus (GCRV) is a severe virus that causes great losses to grass carp culture every year, and GCRV-II is the current popular and fatal strain. VP56, fibrin on the outer surface of GCRV-II, mediates cell attachment. In this study, we firstly
Yang Gao, Xingchen Huo, Zhensheng Wang, Gailing Yuan, Xiaoling Liu, Taoshan Ai, Jianguo Su   +6 more
doaj   +1 more source

A Review of Intra‐ and Extracellular Antigen Delivery Systems for Virus Vaccines of Finfish

Journal of Immunology Research, Volume 2015, Issue 1, 2015., 2015
Vaccine efficacy in aquaculture has for a long time depended on evaluating relative percent survival and antibody responses after vaccination. However, current advances in vaccine immunology show that the route in which antigens are delivered into cells is deterministic of the type of adaptive immune response evoked by vaccination.
Hetron Mweemba Munang’andu, Øystein Evensen, Kurt Blaser   +2 more
wiley   +1 more source