Results 41 to 50 of about 753 (151)

Piscine Vitamin D Receptors Vdra/Vdrb in the Absence of Vitamin D Are Utilized by Grass Carp Reovirus for Promoting Viral Replication

open access: yesMicrobiology Spectrum, 2023
The vitamin D receptor (VDR) plays a pivotal role in the biological actions of vitamin D (VitD). However, little is known about the functions of VDR in the production of viral inclusion bodies (VIBs). Using a representative strain of grass carp reovirus (
Yun Jie Song   +6 more
doaj   +1 more source

Advances in research of biological functions of Isthmin‐1

open access: yesJournal of Cell Communication and Signaling, Volume 17, Issue 3, Page 507-521, September 2023., 2023
Graphical abstract The main biological functions of ISM1. Current studies on the biological functions of ISM1 focus on growth and development, metabolism, and anticancer treatment. During embryonic development, ISM1 is dynamically expressed in the zebrafish, African clawed frog, chick, mouse, and human, is associated with craniofacial malformations ...
Li Menghuan   +6 more
wiley   +1 more source

Grass carp SERPINA1 inhibits GCRV infection through degrading CF2

open access: yesFrontiers in Immunology, 2022
SERPINA1, a member of the serine protease inhibitor family, plays a role in viral infection and inflammation by regulating the activities of serine and cysteine proteases.
Yangyang Li   +14 more
doaj   +1 more source

Single‐cell transcriptome profiling reveals diverse immune cell populations and their responses to viral infection in the spleen of zebrafish

open access: yesThe FASEB Journal, Volume 37, Issue 6, June 2023., 2023
A comprehensive atlas of immune cell types in zebrafish was generated on the basis of single‐cell transcriptome profiling. The splenic leukocytes were collected from adult zebrafish that were administered with mock phosphate‐buffered saline, infected with spring viremia of carp virus (SVCV), and vaccinated with inactivated SVCV plus infected with ...
Chong‐Bin Hu   +7 more
wiley   +1 more source

Pro-inflammatory regulatory mechanism of C5a/C5aR pathway in GCRV-infected grass carp (Ctenopharyngodon idella)

open access: yesAquaculture Reports, 2023
Death of grass carp (Ctenopharyngodon idella) caused by grass carp reovirus (GCRV) infection severely restricts the development of the grass carp industry.
Baohong Xu   +8 more
doaj   +1 more source

Fish disease prevention via microbial dysbiosis‐associated biomarkers in aquaculture

open access: yesReviews in Aquaculture, Volume 15, Issue 2, Page 579-594, March 2023., 2023
Abstract Infectious diseases are a major burden in aquaculture, and represent a significant yield‐limiting factor in production that is costly to manage as well as a potential vector for zoonoses. Over the past decades, a range of new diseases have emerged, alongside increased levels of antibiotic resistance, thus heightening the need for improved ...
Julia Mougin, Alyssa Joyce
wiley   +1 more source

Characterization, Expression, and Ligand Binding of LGP2 and MDA5 in Largemouth Black Bass Micropterus salmoides (Lacepède, 1802)

open access: yesAquaculture Research, Volume 2023, Issue 1, 2023., 2023
Melanoma differentiation‐associated gene 5 (MDA5) and the laboratory of genetics and physiology 2 (LGP2) are family members of retinoic acid‐inducible gene I (RIG‐I)‐like receptors (RLRs), which play important roles in the immune response against pathogens invasion.
Xiangyu Pi   +6 more
wiley   +1 more source

Complete Genome Sequence of a Reovirus Isolated from Grass Carp, Indicating Different Genotypes of GCRV in China [PDF]

open access: yesJournal of Virology, 2012
ABSTRACT A widespread grass carp hemorrhagic disease (GCHD) caused by grass carp reovirus (GCRV) has been known in China since 1983. A virulent reovirus strain, HZ08, was isolated from diseased grass carp in Zhejiang Province, China. We sequenced and analyzed the complete genome of strain HZ08 and compared it with published GCRV genome ...
Qing, Wang   +6 more
openaire   +2 more sources

Selection of functional EPHB2 genotypes from ENU mutated grass carp treated with GCRV

open access: yesBMC Genomics, 2021
Background N-ethyl-N-nitrosourea (ENU) mutagenesis is a useful method for the genetic engineering of plants, and the production of functional mutants in animal models including mice and zebrafish.
Meher un Nissa   +3 more
doaj   +1 more source

Multi-Omics Sequencing Provides Insights Into Age-Dependent Susceptibility of Grass Carp (Ctenopharyngodon idellus) to Reovirus

open access: yesFrontiers in Immunology, 2021
Grass carp (Ctenopharyngodon idellus) is an important aquaculture species in China that is affected by serious diseases, especially hemorrhagic disease caused by grass carp reovirus (GCRV). Grass carp have previously shown age-dependent susceptibility to
Libo He   +12 more
doaj   +1 more source

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