Results 71 to 80 of about 9,076 (199)

Comparative study of the immunoprotective effect of two grass carp-sourced Bacillus subtilis spore-based vaccines against grass carp reovirus [PDF]

open access: yes, 2019
Grass carp reovirus II (GCRV II) causes severe haemorrhagic disease with high mortality in grass carp, Cyenopharyngodon idellus. Vaccination is a very effective method in conferring protection against GCRV.
Zhou, Yuan-Yuan   +6 more
core   +2 more sources

Selection of functional EPHB2 genotypes from ENU mutated grass carp treated with GCRV

open access: yesBMC Genomics, 2021
Background N-ethyl-N-nitrosourea (ENU) mutagenesis is a useful method for the genetic engineering of plants, and the production of functional mutants in animal models including mice and zebrafish.
Meher un Nissa   +3 more
doaj   +1 more source

Distinct expression profiles and overlapping functions of IL-4/13A and IL-4/13B in grass carp (Ctenopharyngodon idella)

open access: yesAquaculture and Fisheries, 2020
In mammals, interleukin (IL)-4 and IL-13 are important cytokines involved in the immune response of the host defence against pathogens and play critical roles in the polarization of monocytes/macrophages (MO/Mϕs). However, in teleost fish, the role of IL-
Xinyu Jiang   +7 more
doaj   +1 more source

Oral PLGA-based DNA vaccines using interferons as adjuvants remarkably promote the immune protection of grass carp (Ctenopharyngodon idella) against GCRV infection

open access: yesWater Biology and Security, 2023
Grass carp hemorrhagic disease caused by grass carp reovirus (GCRV) results in significant economic losses to the global grass carp aquaculture industry. Oral vaccination is an ideal choice for disease precaution in aquaculture. However, oral vaccine can
Chaolin Jiang   +6 more
doaj   +1 more source

Structure and function of S9 segment of grass carp reovirus Anhui strain. [PDF]

open access: yesVirusdisease, 2017
A highly virulent grass carp reovirus (GCRV) strain, named GCRV-AH528, was recently purified from a diseased grass carp with hemorrhage disease in Anhui, China. GCRV-AH528 S9 segment was 1320 nucleotides in length and encoded a 418 amino acid VP6 protein.
Wu M   +6 more
europepmc   +4 more sources

The Role of Gut Microbiota in Fish Viral Infection: Mechanisms and Microbiota‐Targeted Interventions

open access: yesAquaculture Nutrition, Volume 2026, Issue 1, 2026.
Viral diseases represent one of the major threats to the global aquaculture industry. In recent years, the relationship between gut microbiota and viral infections in fish has garnered increasing attention. The gut microbiota contributes critically to fish health and is involved in antiviral defense through immune regulation, secretion of microbial ...
Qiong Zhao   +4 more
wiley   +1 more source

The effects of GCRV on various tissues of grass carp (Ctenopharyngodon idella) and identification of differential interferon-stimulating genes (ISGs) through muscle transcriptome analysis

open access: yesEcotoxicology and Environmental Safety
Grass carp hemorrhagic disease is caused by the grass carp reovirus (GCRV). The disease spreads rapidly and has a high fatality rate, which seriously affects grass carp culture. Moreover, the molecular mechanisms underlying grass carp hemorrhagic disease
Ziquan Yang   +5 more
doaj   +1 more source

Molecular basis of pathogenesis of emerging viruses infecting aquatic animals

open access: yesAquaculture and Fisheries, 2018
Aquatic vertebrates are very abundant in the world, and they are of tremendous importance in providing global food security and nutrition. However, emergent and resurgent viruses, such as ranavirus (e.g., Rana grylio virus, RGV and Andriasd avidianus ...
Lang Gui   +2 more
doaj   +1 more source

Characterization of IL-22 Bioactivity and IL-22-Positive Cells in Grass Carp Ctenopharyngodon idella

open access: yesFrontiers in Immunology, 2020
Interleukin (IL)-22 plays an important role in regulating inflammation and clearance of infectious pathogens. IL-22 homologs have been discovered in fish, but the functions and sources of IL-22 have not been fully characterized.
Yibin Yang   +27 more
doaj   +1 more source

Novel Duck Orthoreovirus Induces Ferroptosis in HD11 Cells by Hijacking Cellular Iron Metabolism and Promoting Iron Accumulation

open access: yesTransboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Novel duck orthoreovirus (NDRV) infection induces severe splenic necrosis in ducks, resulting in a cascade of detrimental consequences, including immunosuppression, secondary infections, and diminished vaccine efficacy. Avian orthoreovirus (ARV) exhibits high tropism for macrophages, with splenic macrophages being identified as the primary target cells
Hongzhi Wang   +6 more
wiley   +1 more source

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