A comprehensive atlas of immune cell types in zebrafish was generated on the basis of single‐cell transcriptome profiling. The splenic leukocytes were collected from adult zebrafish that were administered with mock phosphate‐buffered saline, infected with spring viremia of carp virus (SVCV), and vaccinated with inactivated SVCV plus infected with ...
Chong‐Bin Hu +7 more
wiley +1 more source
Applying genetic technologies to combat infectious diseases in aquaculture
Abstract Disease and parasitism cause major welfare, environmental and economic concerns for global aquaculture. In this review, we examine the status and potential of technologies that exploit genetic variation in host resistance to tackle this problem.
Nicholas A. Robinson +36 more
wiley +1 more source
Fish disease prevention via microbial dysbiosis‐associated biomarkers in aquaculture
Abstract Infectious diseases are a major burden in aquaculture, and represent a significant yield‐limiting factor in production that is costly to manage as well as a potential vector for zoonoses. Over the past decades, a range of new diseases have emerged, alongside increased levels of antibiotic resistance, thus heightening the need for improved ...
Julia Mougin, Alyssa Joyce
wiley +1 more source
Genome‐wide association and genomic selection in aquaculture
Abstract Recent advancements in genomic technologies have led to the discovery and application of DNA‐markers [e.g. single nucleotide polymorphisms (SNPs)] for the genetic improvement of several aquaculture species. The identification of specific genomic regions associated with economically important traits, using, for example, genome‐wide association ...
José M. Yáñez +6 more
wiley +1 more source
Melanoma differentiation‐associated gene 5 (MDA5) and the laboratory of genetics and physiology 2 (LGP2) are family members of retinoic acid‐inducible gene I (RIG‐I)‐like receptors (RLRs), which play important roles in the immune response against pathogens invasion.
Xiangyu Pi +6 more
wiley +1 more source
Complete genome sequence and comparative analysis of grass carp reovirus strain 109 (GCReV-109) with other grass carp reovirus strains reveals no significant correlation with regional distribution [PDF]
A new grass carp reovirus strain, tentatively named GCReV-109, was isolated in Hubei, China, and its complete genome sequence was determined. The genome contained 11 double-stranded RNA segments (S1-S11) covering 24,620 base pairs.
Pei, Chao +3 more
core +1 more source
GCRV 096 VP6 protein and its impacts on GCRV replication with different genotypes in CIK cells
Grass carp reovirus (GCRV) is the causative agent of grass carp hemorrhagic disease, which has detrimental effects on the grass carp aquaculture industry. There are four known genotypes of GCRV and strains of different GCRV genotypes differ greatly.
Xiuying Yan +6 more
doaj +1 more source
Isolation and analysis of a novel grass carp toll-like receptor 4 (tlr4) gene cluster involved in the response to grass carp reovirus [PDF]
The mammalian response to lipopolysaccharide (LPS) is mainly mediated by Toll-Like Receptor 4 (TLR4). Fish and mammalian TLR4 vary; fish TLR4 ligands are unknown. Isolation of fish tlr4 genes is difficult due to their complex genomic structure.
Wang, YP (reprint author), Chinese Acad Sci, Inst Hydrobiol, Ctr Fish Biol & Fishery Biotechnol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Hubei, Peoples R China. +6 more
core +1 more source
Background Grass carp are an important farmed fish in China that are infected by many pathogens, especially grass carp reovirus (GCRV). Notably, grass carp showed age-dependent susceptibility to GCRV; that is, grass carp not older than one year were ...
Libo He +7 more
doaj +1 more source
Molecular cloning of grass carp (Ctenopharyngodon idellus) T-bet and GATA-3, and their expression profiles with IFN-gamma in response to grass carp reovirus (GCRV) infection [PDF]
Both T-bet and GATA-3, Th1/Th2 lineage-specific transcription factors, play important roles in the development of T cells and Th1/Th2 differentiation. In this study, T-bet and GATA-3 genes were cloned from grass carp (Ctenopharyngodon idellus).
Guo, Qionglin +5 more
core +1 more source

