Results 21 to 30 of about 270,527 (148)

Grass carp reovirus activates fish Ppp1r3g to suppress innate immunity and exacerbate hemorrhage via the 14-3-3ζ/Itgb3 signaling axis. [PDF]

PLoS Pathogens
Protein phosphatase 1 regulatory subunit 3G (PPP1R3G) is one of the regulatory subunits of protein phosphatase 1 (PP1). Current research on PPP1R3G is primarily focused on glycogen synthesis and lipid metabolism.
Ruyi Wang, Man Zhou, Yuxuan Wang, Xudong Hu, Han Zhang, Hong Cao   +5 more
doaj   +2 more sources

Comparative Transcriptomics Analysis Reveals Unique Immune Response to Grass Carp Reovirus Infection in Barbel Chub (Squaliobarbus curriculus) [PDF]

Biology
Grass carp (Ctenopharyngodon idella) and barbel chub (Squaliobarbus curriculus)—both Leuciscinae subfamily species—demonstrate differences in grass carp reovirus (GCRV) infection resistance.
Yuhong Huang, Xiaodong Wang, Zhao Lv, Xudong Hu, Baohong Xu, Hong Yang, Tiaoyi Xiao, Qiaolin Liu   +7 more
doaj   +2 more sources

Characterization of grass carp FosB, Fosl2, JunD transcription factors in response to GCRV infection

Aquaculture and Fisheries, 2022
Activating protein-1 (AP-1) composed of Jun and Fos family proteins, which are frequently activated by pathogens to induce cellular inflammation and immune responses. In this study, by using RNA sequencing (RNA-seq) technology, we found that FosB, Fosl2,
Fei Yu, Wanjuan Li, Longlong Wang, Shunzheng Que, Liqun Lu   +4 more
doaj   +1 more source

Grass carp SERPINA1 inhibits GCRV infection through degrading CF2

Frontiers in Immunology, 2022
SERPINA1, a member of the serine protease inhibitor family, plays a role in viral infection and inflammation by regulating the activities of serine and cysteine proteases.
Yangyang Li, Yangyang Li, Liangming Chen, Liangming Chen, Rong Huang, Yangyu Li, Yangyu Li, Cheng Yang, Bin Gui, Bin Gui, Yongming Li, Lanjie Liao, Zuoyan Zhu, Yaping Wang, Yaping Wang   +14 more
doaj   +1 more source

Pro-inflammatory regulatory mechanism of C5a/C5aR pathway in GCRV-infected grass carp (Ctenopharyngodon idella)

Aquaculture Reports, 2023
Death of grass carp (Ctenopharyngodon idella) caused by grass carp reovirus (GCRV) infection severely restricts the development of the grass carp industry.
Baohong Xu, Hang Su, Changjun Chen, Qiaolin Liu, Tiaoyi Xiao, Yi Liu, Zhao Lv, Hongquan Wang, Zheyu Wen   +8 more
doaj   +1 more source

Advances in research of biological functions of Isthmin‐1

Journal of Cell Communication and Signaling, Volume 17, Issue 3, Page 507-521, September 2023., 2023
Graphical abstract The main biological functions of ISM1. Current studies on the biological functions of ISM1 focus on growth and development, metabolism, and anticancer treatment. During embryonic development, ISM1 is dynamically expressed in the zebrafish, African clawed frog, chick, mouse, and human, is associated with craniofacial malformations ...
Li Menghuan, Yang Yang, Ma Qianhe, Zhang Na, Cao Shicheng, Chang Bo, Y. I. XueJie   +6 more
wiley   +1 more source

Cloning of Grass Carp Chemokine XC Receptor 1 (XCR1) Gene and Evaluation of Its Expression in Various Organs after GCRV Infection

Fishes, 2022
Interaction between the chemokine receptor XCR1 and its ligand is closely related to the immune function in animals; however, there are only a few reports on role of XCR1 in the immune system of fish. We aimed to analyze the expression of XCR1 in various
Hailuo Yu, Yi Liu, Tiaoyi Xiao, Hongquan Wang, Baohong Xu   +4 more
doaj   +1 more source

Comparative acetylomic analysis reveals differentially acetylated proteins regulating fungal metabolism in hypovirus‐infected chestnut blight fungus

Molecular Plant Pathology, Volume 24, Issue 9, Page 1126-1138, September 2023., 2023
Comparison of Cryphonectria parasitica with or without hypovirus found differentially acetylated proteins were enriched in metabolic processes; the acetylation of citrate synthase lysine‐55 plays a vital role in its activity. Abstract Cryphonectria parasitica, the chestnut blight fungus, and hypoviruses are excellent models for examining fungal ...
Ru Li, Fengyue Chen, Shuangcai Li, Luying Yuan, Lijiu Zhao, Shigen Tian, Baoshan Chen   +6 more
wiley   +1 more source

Single‐cell transcriptome profiling reveals diverse immune cell populations and their responses to viral infection in the spleen of zebrafish

The FASEB Journal, Volume 37, Issue 6, June 2023., 2023
A comprehensive atlas of immune cell types in zebrafish was generated on the basis of single‐cell transcriptome profiling. The splenic leukocytes were collected from adult zebrafish that were administered with mock phosphate‐buffered saline, infected with spring viremia of carp virus (SVCV), and vaccinated with inactivated SVCV plus infected with ...
Chong‐Bin Hu, Jie Wang, Yun Hong, Hao Li, Dong‐Dong Fan, Ai‐Fu Lin, Li‐Xin Xiang, Jian‐Zhong Shao   +7 more
wiley   +1 more source

Applying genetic technologies to combat infectious diseases in aquaculture

Reviews in Aquaculture, Volume 15, Issue 2, Page 491-535, March 2023., 2023
Abstract Disease and parasitism cause major welfare, environmental and economic concerns for global aquaculture. In this review, we examine the status and potential of technologies that exploit genetic variation in host resistance to tackle this problem.
Nicholas A. Robinson, Diego Robledo, Lene Sveen, Rose Ruiz Daniels, Aleksei Krasnov, Andrew Coates, Ye Hwa Jin, Luke T. Barrett, Marie Lillehammer, Anne H. Kettunen, Ben L. Phillips, Tim Dempster, Andrea Doeschl‐Wilson, Francisca Samsing, Gareth Difford, Sarah Salisbury, Bjarne Gjerde, John‐Erik Haugen, Erik Burgerhout, Binyam S. Dagnachew, Dominic Kurian, Mark D. Fast, Morten Rye, Marcela Salazar, James E. Bron, Sean J. Monaghan, Celeste Jacq, Mike Birkett, Howard I. Browman, Anne Berit Skiftesvik, David M. Fields, Erik Selander, Samantha Bui, Anna Sonesson, Stanko Skugor, Tone‐Kari Knutsdatter Østbye, Ross D. Houston   +36 more
wiley   +1 more source