Results 21 to 30 of about 1,577 (195)

Protective roles of grass carp Ctenopharyngodon idella Mx isoforms against grass carp reovirus.

PLoS ONE, 2012
BackgroundMyxovirus resistance (Mx) proteins are crucial effectors of the innate antiviral response against a wide range of viruses, mediated by the type I interferon (IFN-I) signaling pathway.
Limin Peng, Chunrong Yang, Jianguo Su, Jianguo Su   +3 more
doaj   +4 more sources

Grass carp reovirus VP56 and VP35 induce formation of viral inclusion bodies for replication [PDF]

iScience
Summary: Viral inclusion bodies (VIBs) are subcellular structures required for efficient viral replication. How type II grass carp reovirus (GCRV-II), the mainly prevalent strain, forms VIBs is unknown.
Chu Zhang, Hui Wu, Hao Feng, Yong-An Zhang, Jiagang Tu   +4 more
doaj   +2 more sources

Grass carp reovirus VP4 manipulates TOLLIP to degrade STING for inhibition of IFN production [PDF]

Journal of Virology
Although fish possess an effective interferon (IFN) system to defend against viral infection, grass carp reovirus (GCRV) still causes epidemic hemorrhagic disease and tremendous economic loss in grass carp.
Yang-Yang Wang, Xue-Li Wang, Zhuo-Cong Li, Can Zhang, Xiao Xu, Bao-Jie Cui, Meng-Ze Tian, Chu-Jing Zhou, Na Xu, Yue Wu, Xiao-Li Yang, Dan-Dan Chen, Long-Feng Lu, Shun Li   +13 more
doaj   +2 more sources

Comparative Transcriptomics Analysis Reveals Unique Immune Response to Grass Carp Reovirus Infection in Barbel Chub (Squaliobarbus curriculus) [PDF]

Biology
Grass carp (Ctenopharyngodon idella) and barbel chub (Squaliobarbus curriculus)—both Leuciscinae subfamily species—demonstrate differences in grass carp reovirus (GCRV) infection resistance.
Yuhong Huang, Xiaodong Wang, Zhao Lv, Xudong Hu, Baohong Xu, Hong Yang, Tiaoyi Xiao, Qiaolin Liu   +7 more
doaj   +2 more sources

Type II Grass Carp Reovirus Infects Leukocytes but Not Erythrocytes and Thrombocytes in Grass Carp (Ctenopharyngodon idella). [PDF]

Viruses, 2021
Grass carp reovirus (GCRV) causes serious losses to the grass carp industry. At present, infectious tissues of GCRV have been studied, but target cells remain unclear. In this study, peripheral blood cells were isolated, cultured, and infected with GCRV.
Yang L, Su J.
europepmc   +5 more sources

Functional investigation of grass carp reovirus nonstructural protein NS80 [PDF]

Virology Journal, 2011
Background Grass Carp Reovirus (GCRV), a highly virulent agent of aquatic animals, has an eleven segmented dsRNA genome encased in a multilayered capsid shell, which encodes twelve proteins including seven structural proteins (VP1-VP7), and five ...
Shao Ling, Sun Xiaoyun, Cai Lin, Fang Qin   +3 more
doaj   +3 more sources

Temperature-regulated type II grass carp reovirus establishes latent infection in Ctenopharyngodon idella brain [PDF]

Virologica Sinica, 2023
Yong-An Zhang, Jianguo Su
exaly   +2 more sources

Differences in responses of grass carp to different types of grass carp reovirus (GCRV) and the mechanism of hemorrhage revealed by transcriptome sequencing [PDF]

BMC Genomics, 2017
Background Grass carp is an important farmed fish in China that is affected by serious disease, especially hemorrhagic disease caused by grass carp reovirus (GCRV).
Libo He, Aidi Zhang, Yongyan Pei, Pengfei Chu, Yongming Li, Rong Huang, Lanjie Liao, Zuoyan Zhu, Yaping Wang   +8 more
doaj   +3 more sources

Sialic acid serves as a functional receptor for grass carp reovirus. [PDF]

PLoS Pathog
Grass carp reovirus (GCRV) causes hemorrhagic disease and substantial economic losses in the aquaculture of grass carp ( Ctenopharyngodon idella ), a commercially important fish species in China.
Wang Q, Peng Z, Gui B, Li Y, Liao L, Zhu Z, Wang Y, He L.   +7 more
europepmc   +3 more sources

Characterization of grass carp FosB, Fosl2, JunD transcription factors in response to GCRV infection

Aquaculture and Fisheries, 2022
Activating protein-1 (AP-1) composed of Jun and Fos family proteins, which are frequently activated by pathogens to induce cellular inflammation and immune responses. In this study, by using RNA sequencing (RNA-seq) technology, we found that FosB, Fosl2,
Fei Yu, Wanjuan Li, Longlong Wang, Shunzheng Que, Liqun Lu   +4 more
doaj   +1 more source