As a member of the pattern recognition receptor (PRR) class, scavenger receptor class B type 1 (SRB1) plays a key role in innate immunity. Grass carp (Ctenopharyngodon idellus) ranks among the most extensively cultivated freshwater aquaculture species in
Yang Zhang +9 more
doaj +2 more sources
Global and Complement Gene-Specific DNA Methylation in Grass Carp after Grass Carp Reovirus (GCRV) Infection. [PDF]
Grass carp reovirus (GCRV) causes huge economic loss to the grass carp cultivation industry but the mechanism remains largely unknown. In this study, we investigated the global and complement gene-specific DNA methylation in grass carp after GCRV infection aimed to uncover the mechanism underlying GCRV infection.
Xiong L +7 more
europepmc +5 more sources
Grass carp reovirus VP56 and VP35 induce formation of viral inclusion bodies for replication [PDF]
Summary: Viral inclusion bodies (VIBs) are subcellular structures required for efficient viral replication. How type II grass carp reovirus (GCRV-II), the mainly prevalent strain, forms VIBs is unknown.
Chu Zhang +4 more
doaj +2 more sources
Grass carp reovirus VP4 manipulates TOLLIP to degrade STING for inhibition of IFN production [PDF]
Although fish possess an effective interferon (IFN) system to defend against viral infection, grass carp reovirus (GCRV) still causes epidemic hemorrhagic disease and tremendous economic loss in grass carp.
Yang-Yang Wang +13 more
doaj +2 more sources
Comparative Transcriptomics Analysis Reveals Unique Immune Response to Grass Carp Reovirus Infection in Barbel Chub (Squaliobarbus curriculus) [PDF]
Grass carp (Ctenopharyngodon idella) and barbel chub (Squaliobarbus curriculus)—both Leuciscinae subfamily species—demonstrate differences in grass carp reovirus (GCRV) infection resistance.
Yuhong Huang +7 more
doaj +2 more sources
Grass carp (Ctenopharyngodon idellus) is an economical aquaculture species in China, and the Grass Carp Reovirus (GCRV) that causes hemorrhagic disease seriously affects the grass carp cultivation industry. Substantial evidence indicates that there is an association between the membrane-associated RING-CH family of E3 ligase (MARCH) family and immune ...
Mi, Ou +9 more
openaire +3 more sources
Characterization of grass carp reovirus minor core protein VP4 [PDF]
Background Grass Carp Reovirus (GCRV), a tentative member in the genus Aquareovirus of family Reoviridae, contains eleven segmented (double-stranded RNA) dsRNA genome which encodes 12 proteins.
Yan Liming +4 more
doaj +3 more sources
Functional investigation of grass carp reovirus nonstructural protein NS80 [PDF]
Background Grass Carp Reovirus (GCRV), a highly virulent agent of aquatic animals, has an eleven segmented dsRNA genome encased in a multilayered capsid shell, which encodes twelve proteins including seven structural proteins (VP1-VP7), and five ...
Shao Ling +3 more
doaj +3 more sources
Grass carp catalase inhibits GCRV replication through ROS scavenging-mediated immune suppression and autophagy [PDF]
Catalase (CAT) is a key antioxidant enzyme that eliminates reactive oxygen species (ROS), thereby protecting organisms from oxidative stress and maintaining cellular homeostasis.
Xuyang Wang +11 more
doaj +2 more sources
Temperature-regulated type II grass carp reovirus establishes latent infection in Ctenopharyngodon idella brain [PDF]
Yong-An Zhang, Jianguo Su
exaly +2 more sources

