Results 11 to 20 of about 9,076 (199)

Identification, Virulence, and Molecular Characterization of a Recombinant Isolate of Grass Carp Reovirus Genotype I [PDF]

Viruses, 2021
The hemorrhagic disease of grass carp (HDGC) caused by grass carp reovirus (GCRV) still poses a great threat to the grass carp industry. Isolation and identification of the GCRV genotype I (GCRV-I) has been rarely reported in the past decade.
Weiwei Zeng, Sven M. Bergmannc, Hanxu Dong, Ying Yang, Minglin Wu, Hong Liu, Yanfeng Chen, Hua Li   +7 more
doaj   +4 more sources

Isolation, Identification, and Genomic Analysis of a Novel Reovirus from Healthy Grass Carp and Its Dynamic Proliferation In Vitro and In Vivo [PDF]

Viruses, 2021
A new grass carp reovirus (GCRV), healthy grass carp reovirus (HGCRV), was isolated from grass carp in 2019. Its complete genome sequence was determined and contained 11 dsRNAs with a total size of 23,688 bp and 57.2 mol% G+C content, encoding 12 ...
Lingbing Zeng, Vikram Vakharia, Yuding Fan   +2 more
exaly   +6 more sources

Comparative Transcriptomic Analysis Revealed Potential Differential Mechanisms of Grass Carp Reovirus Pathogenicity. [PDF]

Int J Mol Sci, 2023
Grass carp reovirus (GCRV), one of the most serious pathogens threatening grass carp (Ctenopharyngodon idella), can lead to grass carp hemorrhagic disease (GCHD). Currently, GCRV can be divided into three genotypes, but the comparison of their pathogenic
Kong W, Ding G, Yang P, Li Y, Cheng G, Cai C, Xiao J, Feng H, Xu Z.   +8 more
europepmc   +4 more sources

Sialic acid serves as a functional receptor for grass carp reovirus. [PDF]

PLoS Pathog
Grass carp reovirus (GCRV) causes hemorrhagic disease and substantial economic losses in the aquaculture of grass carp (Ctenopharyngodon idella), a commercially important fish species in China.
Wang Q, Peng Z, Gui B, Li Y, Liao L, Zhu Z, Wang Y, He L.   +7 more
europepmc   +4 more sources

Insights into the Antiviral Immunity against Grass Carp (Ctenopharyngodon idella) Reovirus (GCRV) in Grass Carp [PDF]

Journal of Immunology Research, 2015
Global fish production from aquaculture has rapidly grown over the past decades, and grass carp shares the largest portion. However, hemorrhagic disease caused by grass carp reovirus (GCRV) results in tremendous loss of grass carp (Ctenopharyngodon ...
Youliang Rao, Jianguo Su
doaj   +7 more sources

Global and Complement Gene-Specific DNA Methylation in Grass Carp after Grass Carp Reovirus (GCRV) Infection [PDF]

International Journal of Molecular Sciences, 2018
Grass carp reovirus (GCRV) causes huge economic loss to the grass carp cultivation industry but the mechanism remains largely unknown. In this study, we investigated the global and complement gene-specific DNA methylation in grass carp after GCRV infection aimed to uncover the mechanism underlying GCRV infection.
Libo He, Lv Xiong, Zuoyan Zhu
exaly   +7 more sources

Protective roles of grass carp Ctenopharyngodon idella Mx isoforms against grass carp reovirus. [PDF]

PLoS ONE, 2012
BackgroundMyxovirus resistance (Mx) proteins are crucial effectors of the innate antiviral response against a wide range of viruses, mediated by the type I interferon (IFN-I) signaling pathway.
Limin Peng, Chunrong Yang, Jianguo Su, Jianguo Su   +3 more
doaj   +5 more sources

Grass Carp Prx 3 Elevates Host Antioxidant Activity and Induces Autophagy to Inhibit Grass Carp Reovirus (GCRV) Replication [PDF]

Antioxidants, 2022
Peroxiredoxins are a family of antioxidant proteins that protect cells from oxidative damage caused by reactive oxygen species (ROS). Herein, the peroxiredoxin 3 gene from grass carp (Ctenopharyngodon idellus), named CiPrx3, was cloned and analyzed.
Xinyu Liang, Yongming Li, Pengfei Chu, Qian Wang, Hanyue Wang, Lanjie Liao, Cheng Yang, Zuoyan Zhu, Yaping Wang, Libo He   +9 more
doaj   +4 more sources

Biochemical profiling of the protein encoded by grass carp reovirus genotype II. [PDF]

iScience
Summary In this study, we obtained the whole genome sequence of GCRV-DY197 and investigated the localization, post-translational modifications, and host interactions of the 11 viral proteins encoded by GCRV-DY197 in grass carp ovary (GCO) cells.
Liu M, Xu C, Zhou Y, Xue M, Jiang N, Li Y, Huang Z, Meng Y, Liu W, Kong X, Fan Y.   +10 more
europepmc   +5 more sources

Inhibitor analysis revealed that clathrin-mediated endocytosis is involed in cellular entry of type III grass carp reovirus [PDF]

Virology Journal, 2018
Background Grass carp (Ctenopharyngodon idella) hemorrhagic disease is caused by an acute infection with grass carp reovirus (GCRV). The frequent outbreaks of this disease have suppressed development of the grass carp farming industry.
Hao Wang, Weisha Liu, Meng Sun, Dubo Chen, Lingbing Zeng, Liqun Lu, Jing Xie   +6 more
doaj   +4 more sources