Results 141 to 150 of about 4,116,626 (248)

Avian influenza viral nucleocapsid and hemagglutinin proteins induce chicken CD8+ memory T lymphocytes

Virology, 2010
The avian influenza viruses (AIVs) can be highly contagious to poultry and a zoonotic threat to humans. Since the memory CD8(+) T lymphocyte responses in chickens to AIV proteins have not been defined, these responses to H5N9 AIV hemagglutinin (HA) and nucleocapsid (NP) proteins were evaluated by ex vivo stimulation with virus infected non-professional
Singh, Shailbala, Briles, Worthie E., Lupiani, Blanca, Collisson, Ellen W.   +3 more
openaire   +2 more sources

Transmission and pathogenesis of vesicular stomatitis viruses

Brazilian Journal of Veterinary Pathology, 2009
Vesicular Stomatitis (VS) is caused by Vesicular stomatitis viruses (VSV), negative single stranded RNA arthropod-borne members of the Family Rhabdoviridae.
Janildo L. Reis Jr, Danny Mead, Luis L. Rodriguez, Corrie C Brown   +3 more
doaj   +1 more source

Olfactory Tuft Cells Are Critical to Basal Inflammation, Innate Immune Response to Viral Infection, and Modulation of Quiescent Stem Cell Activation, Proliferation and Differentiation

Cell Proliferation, EarlyView.
Olfactory tuft cells communicate with other mucosal cells in maintaining olfactory epithelial immunity and sensory function. Disruption of tuft cell signalling pathways causes a skewed immune response, leading to heightened inflammation and increased activation of the quiescent stem cells, which are further exacerbated by viral infection.
Sai‐Sai Zhang, Haiyan Wang, Yi‐Sen Yang, Yi‐Hong Li, Defu Yu, Yushi Yao, Ruhong Zhou, Liquan Huang   +7 more
wiley   +1 more source

A comparative analysis of cell death signalling in RNA and DNA virus infections and potential inhibitory strategies

The FEBS Journal, EarlyView.
RNA and DNA viruses can manipulate host cell death through various mechanisms. RNA viruses (H1N1, SARS‐CoV‐2) induce acute apoptosis, necroptosis, and pyroptosis to promote rapid viral transmission and epithelial barrier damage. In contrast, DNA viruses (HSV‐1, EBV) regulate these mechanisms to sustain a lytic‐latency cycle, evade immune response and ...
Panagiotis Keramidas, Maria Pitou, Amalia Aggeli, Sotiris Varlamis, Theodora Choli‐Papadopoulou   +4 more
wiley   +1 more source

Effects of phosphorylation of avian retrovirus nucleocapsid protein pp12 on binding of viral RNA.

Journal of Biological Chemistry, 1984
The major nucleocapsid protein of avian retroviruses, pp12, preferentially binds to the single-stranded regions of 60 S viral RNA with a apparent binding constant (Kapp) of 1.2 X 10(11) M-1. If the phosphate associated with serine residues of pp12 is hydrolyzed by either alkali treatment or with partially purified phosphoprotein phosphatase activities ...
J, Leis, S, Johnson, L S, Collins, J A, Traugh   +3 more
openaire   +2 more sources

Conformational plasticity of hepatitis C virus core protein enables RNA-induced formation of nucleocapsid-like particles [PDF]

, 2018
Many of the unanswered questions associated with hepatitis C virus assembly are related to the core protein (HCVcp), which forms an oligomeric nucleocapsid encompassing the viral genome. The structural properties of HCVcp have been difficult to quantify,
Daniel Nettels, Nettels, Daniel, Erik D. Holmstrom, Benjamin Schuler, Schuler, Benjamin, Holmstrom, Erik D, Holmstrom ED, Schuler B, Nettels D   +8 more
core   +1 more source

Structural proteins of human coronaviruses: what makes them different?

Frontiers in Cellular and Infection Microbiology
Following COVID-19 outbreak with its unprecedented effect on the entire world, the interest to the coronaviruses increased. The causative agent of the COVID-19, severe acute respiratory syndrome coronavirus – 2 (SARS-CoV-2) is one of seven coronaviruses ...
Nail Minigulov, Kuandyk Boranbayev, Ayaulym Bekbossynova, Bakhytgul Gadilgereyeva, Olena Filchakova   +4 more
doaj   +1 more source

Genome‐scale evidence for host‐associated lineage divergence in the parasitoid, Microctonus aethiopoides

Insect Molecular Biology, EarlyView.
Host associations are primary drivers of genomic divergence, with clear phylogenetic separation observed between strains associated with Hypera and Sitona weevil hosts. Genomic diversity aligns with reproductive modes: sexually reproducing ancestral lineages maintain high heterozygosity, while derived asexual strains exhibit reduced heterozygosity and ...
Meeran Hussain, Elahe Parvizi, Mark R. McNeill, Angela McGaughran   +3 more
wiley   +1 more source

Characterization of the Interaction between hantavirus nucleocapsid protein (N) and ribosomal protein S19 (RPS19

, 2011
Viral ribonucleocapsids harboring the viral genomic RNA are used as the template for viral mRNA synthesis and replication of the viral genome by viral RNA-dependent RNA polymerase (RdRp).
Mary Ashley Rimmer, Sheema Sheema, Zekun Wang, Mohammad A. Mir, Alex Little, Absarul Haque, Islam T.M. Hussein, Erdong Cheng   +7 more
core   +1 more source

Rice Orange Leaf Phytoplasma Imp Protein Blocks G–M Interaction by Binding Glycoprotein G to Suppress Rice Stripe Mosaic Virus Infection

Plant, Cell &Environment, EarlyView.
ABSTRACT Plants frequently encounter multiple pathogens concurrently, yet the molecular bases of pathogen–pathogen interactions during mixed infections remain largely unresolved. Here we show that co‐infection of rice by Rice orange leaf phytoplasma (ROLP) and Rice stripe mosaic virus (RSMV) markedly suppresses RSMV proliferation in both host plants ...
Jiaxin Qiu, Yujiao Zheng, Yanmei Yi, Yuxin Zhang, Tianbao Zeng, Hongyan Chen, Taiyun Wei, Xiao‐Feng Zhang   +7 more
wiley   +1 more source