Results 51 to 60 of about 2,694,187 (254)

Inflammatory Control of Viral Infection

, 2023
Inflammatory responses during virus infection differentially impact the host. Managing inflammatory responses is essential in controlling viral infection and related diseases.
Ritu Chakravarti, Sukanya Chakravarty, Saurabh Chattopadhyay   +2 more
core   +1 more source

Usutu Virus: An Arbovirus on the Rise

Viruses, 2019
The Usutu virus (USUV) is a flavivirus that is drawing increasing attention because of its potential for emergence. First isolated in Africa, it was introduced into Europe where it caused significant outbreaks in birds, such as in Austria in 2001.
Ferdinand Roesch, Alvaro Fajardo, Gonzalo Moratorio, Marco Vignuzzi   +3 more
doaj   +1 more source

Genomic-Scale Interaction Involving Complementary Sequences in the Hepatitis C Virus 5′UTR Domain IIa and the RNA-Dependent RNA Polymerase Coding Region Promotes Efficient Virus Replication

Viruses, 2018
The hepatitis C virus (HCV) genome contains structured elements thought to play important regulatory roles in viral RNA translation and replication processes.
Elodie Rance, Jerome E. Tanner, Caroline Alfieri   +2 more
doaj   +1 more source

Defective viral genomes as therapeutic interfering particles against flavivirus infection in mammalian and mosquito hosts

Nature Communications, 2021
Defective viral genomes (DVGs) can interfere with virus replication and provide a potential approach to control infection. Here, Rezelj et al. use a combined experimental evolution and computational approach to identify DVG sequences that optimally ...
Veronica V. Rezelj, Lucía Carrau, Fernando Merwaiss, Laura I. Levi, Diana Erazo, Quang Dinh Tran, Annabelle Henrion-Lacritick, Valérie Gausson, Yasutsugu Suzuki, Djoshkun Shengjuler, Bjoern Meyer, Thomas Vallet, James Weger-Lucarelli, Veronika Bernhauerová, Avi Titievsky, Vadim Sharov, Stefano Pietropaoli, Marco A. Diaz-Salinas, Vincent Legros, Nathalie Pardigon, Giovanna Barba-Spaeth, Leonid Brodsky, Maria-Carla Saleh, Marco Vignuzzi   +23 more
doaj   +1 more source

Interplay between autophagy and apoptosis in human viral pathogenesis

Virus Research
Highlights • A review elaborating common human DNA/RNA viruses’ autophagy-apoptosis regulation.• Decodes autophagy-apoptosis crosstalk in viral pathogenesis.• Viruses differentially modulates autophagy/apoptosis in different cells for spreading.• Guiding
Qingqing Shao, Tong Liu, Bin Hu, Liu-Qing Chen   +3 more
semanticscholar   +1 more source

A High Frequency of HIV-Specific Circulating Follicular Helper T Cells Is Associated with Preserved Memory B Cell Responses in HIV Controllers

mBio, 2018
Follicular helper T cells (Tfh) play an essential role in the affinity maturation of the antibody response by providing help to B cells. To determine whether this CD4+ T cell subset may contribute to the spontaneous control of HIV infection, we analyzed ...
M. Claireaux, M. Galperin, D. Benati, A. Nouël, M. Mukhopadhyay, J. Klingler, P. de Truchis, D. Zucman, S. Hendou, F. Boufassa, C. Moog, O. Lambotte, L. A. Chakrabarti   +12 more
doaj   +1 more source

Pathogenesis of Respiratory Viral and Fungal Coinfections

Clinical Microbiology Reviews, 2021
Individuals suffering from severe viral respiratory tract infections have recently emerged as “at risk” groups for developing invasive fungal infections.
F. Salazar, E. Bignell, Gordon D. Brown, P. Cook, A. Warris   +4 more
semanticscholar   +1 more source

An Intranasal Virus-Like Particle Vaccine Broadly Protects Mice from Multiple Subtypes of Influenza A Virus

mBio, 2015
Influenza virus infections are a global public health problem, with a significant impact of morbidity and mortality from both annual epidemics and pandemics.
Louis M. Schwartzman, Andrea L. Cathcart, Lindsey M. Pujanauski, Li Qi, John C. Kash, Jeffery K. Taubenberger   +5 more
doaj   +1 more source

Biomarkers of Cellular Stress Do Not Associate with sCD14 in Progressive HIV and SIV Infections in Vivo

Pathogens and Immunity, 2020
Background: Microbial translocation occurs after damage to the structural and/or immunological barrier of the gastrointestinal (GI) tract into circulation.
Carol L. Vinton, Carly E. Starke, Alexandra M. Ortiz, Stephen H. Lai, Jacob K. Flynn, Ornella Sortino, Kenneth Knox, Irini Sereti, Jason Brenchley   +8 more
doaj   +1 more source

Widespread and dynamic expression of granzyme C by skin-resident antiviral T cells

Frontiers in Immunology, 2023
After recognition of cognate antigen (Ag), effector CD8+ T cells secrete serine proteases called granzymes in conjunction with perforin, allowing granzymes to enter and kill target cells.
Ramon A. Lujan, Ramon A. Lujan, Luxin Pei, John P. Shannon, Nathânia Dábilla, Patrick T. Dolan, Heather D. Hickman   +6 more
doaj   +1 more source