Results 181 to 190 of about 1,527,964 (244)

LncRNA ckATP1A1-AS1 inhibits influenza A virus replication by mediating innate immune responses and suppressing viral nuclear import. [PDF]

J Virol
Fan M, Liu Z, Deng L, Zheng Y, Zeng Y, Zhang Y, Su J, Xia J, Ping J.   +8 more
europepmc   +1 more source

Olaparib‐associated cutaneous vasculitis in a patient with breast cancer

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Marcial Álvarez‐Salafranca, Teresa Puértolas, Adrián Diago, María Carmen Gómez‐Mateo   +3 more
wiley   +1 more source

Interleukin‐12: Central Roles in Immune Regulation and Disease Therapy

Immunology &Cell Biology, EarlyView.
IL‐12 levels are tightly regulated to balance effective protective immunity against infections and cancer with the risk of excessive inflammation and autoimmune disease. Both insufficient and excessive IL‐12 activity can therefore be detrimental, highlighting the importance of precisely controlling its production and signaling. ABSTRACT Interleukin‐12 (
Anthi Psoma, Geert van den Bogaart
wiley   +1 more source

Lysophosphatidic acid promotes lipid metabolism through AMPK signaling to support Coxsackievirus infection. [PDF]

J Virol
LoMascolo NJ, Thomas CE, Lange ML, Mounce BC.   +3 more
europepmc   +1 more source

Management of Non‐Plaque‐Induced Gingival Conditions: A Systematic Review—Part 2: Inflammatory and Immune Conditions; Neoplasms; and Gingival Pigmentation

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Aims This systematic review assesses current evidence on the management of non‐plaque (dental biofilm)‐induced gingival diseases and conditions (NPIGDs), including (i) inflammatory and immune conditions, (ii) neoplasms and (iii) gingival pigmentations.
Maria Clotilde Carra, Cecile Wasielewski, Bruno Špiljak, Maja Sabalić‐Schoener, Sebastien Jungo, Ivan Alajbeg   +5 more
wiley   +1 more source

Identifying a broad-spectrum influenza inhibitor that blocks multiple functions of viral NS1 protein. [PDF]

Nat Commun
Zhang Y, Luo Y, Gai W, Wang J, Huang L, Wang Z, Sun L, Jiao W, Wang W, Li D.   +9 more
europepmc   +1 more source

Shotgun Metagenomic Analysis Reveals Taxonomic and Functional Transitions in the Salivary Microbiome During Periodontal Disease Progression

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Aim To characterise multi‐kingdom salivary microbiome profiles across clinically defined periodontal states and identify stage‐specific taxonomic and functional alterations using shotgun metagenomic sequencing. Materials and Methods In this cross‐sectional study, 204 adults (mean age 40.3 ± 7.6 years) from the SECRETO study (NCT01934725 ...
Muhammed Manzoor, Jaakko Leskelä, Eija Könönen, Leo Lahti, Jukka Putaala, Pirkko J. Pussinen, Susanna Paju   +6 more
wiley   +1 more source

The worldwide burden of skin diseases: Lessons from the Global Burden of Disease data

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Skin diseases are a major public health concern worldwide, causing significant personal, economic and social burdens. The Global Burden of Disease (GBD) initiative provides valuable insights but underestimates the burden of skin diseases, emphasizing the urgent need for improved data collection and global collaboration among stakeholders.
Luigi Naldi, Simone Cazzaniga, Carsten Flohr, Marco May Lee, Claire Fuller, Roderick Hay, Esther E. Freeman, Rashmi Sarkar, Ricardo Romiti, Antonio Torrelo, Qianjin Lu, Ncoza Dlova, Visnja Zaborski Breton, Jennifer Austin, Matthias Augustin, Henry Lim, Luca Borradori   +16 more
wiley   +1 more source

A Naturally Occurring Novel Reassortant Strain of Infectious Bursal Disease Virus from Quails. [PDF]

Vet Sci
Guo P, Guo X, Yu C, Gao W, Xie Q, Li T, Wan Z, Qin A, Shao H, Ye J.   +9 more
europepmc   +1 more source

European Consortium for Lipodystrophies consensus definition and classification framework for monogenic lipodystrophy

Journal of Internal Medicine, EarlyView.
Abstract Lipodystrophy comprises a heterogeneous group of disorders characterized by reduced adipose tissue often associated with severe metabolic complications. Lipodystrophy may be genetic, acquired, or secondary to medical therapies initiated for other conditions.
Robert K. Semple, Martin Wabitsch, Baris Akinci, Saif Alyaarubi, Marjoleine F. Broekema, Rebecca J. Brown, Giovanni Ceccarini, Carolina Cecchetti, Solaf M. Elsayed, Antía Fernández‐Pombo, Alessandra Gambineri, Ingrid M. Jazet, Lotte Kleinendorst, Konstanze Miehle, Elif A. Oral, Flavia Prodam, Ferruccio Santini, David B. Savage, Nadia Shaukat Ali, Ekaterina Sorkina, Magdalena Szopa, Marie‐Christine Vantyghem, Camille Vatier, Corinne Vigouroux, Julia von Schnurbein, David Araújo‐Vilar   +25 more
wiley   +1 more source