Results 11 to 20 of about 7,035,314 (359)

SARS-CoV-2 viral proteins NSP1 and NSP13 inhibit interferon activation through distinct mechanisms

PLoS ONE, 2021
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a devastating global pandemic, infecting over 43 million people and claiming over 1 million lives, with these numbers increasing daily.
Christine Vazquez, Sydnie E Swanson, S. Negatu, M. Dittmar, Jesse Miller, H. Ramage, S. Cherry, K. Jurado   +7 more
semanticscholar   +1 more source

Multi-Channel Colocalization Analysis and Visualization of Viral Proteins in Fluorescence Microscopy Images

IEEE Access, 2023
Automatic analysis of colocalizing biological structures in multi-channel fluorescence microscopy images is an important task to quantify and understand biological processes at high spatial-temporal resolution.
Christian Ritter, Roman Thielemann, Ji-Young Lee, Minh Tu Pham, Ralf Bartenschlager, Karl Rohr   +5 more
doaj   +1 more source

Specificity of the HIV-1 Protease on Substrates Representing the Cleavage Site in the Proximal Zinc-Finger of HIV-1 Nucleocapsid Protein

Viruses, 2021
To explore the sequence context-dependent nature of the human immunodeficiency virus type 1 (HIV-1) protease’s specificity and to provide a rationale for viral mutagenesis to study the potential role of the nucleocapsid (NC) processing in HIV-1 ...
János András Mótyán, Márió Miczi, Stephen Oroszlan, József Tőzsér   +3 more
doaj   +1 more source

Genome-wide analysis of protein–protein interactions and involvement of viral proteins in SARS-CoV-2 replication

Cell & Bioscience, 2021
Analysis of viral protein–protein interactions is an essential step to uncover the viral protein functions and the molecular mechanism for the assembly of a viral protein complex. We employed a mammalian two-hybrid system to screen all the viral proteins
Yiling Jiang, Kuijie Tong, R. Yao, Yuanze Zhou, Hanwen Lin, Liubing Du, Yunyun Jin, Liu Cao, Jingquan Tan, Xing-Ding Zhang, D. Guo, Ji-An Pan, Xiaoxue Peng   +12 more
semanticscholar   +1 more source

The Potential of Eukaryotic Cell-Free Systems as a Rapid Response to Novel Zoonotic Pathogens: Analysis of SARS-CoV-2 Viral Proteins

Frontiers in Bioengineering and Biotechnology, 2022
The ongoing pandemic caused by the novel coronavirus (SARS-CoV-2) has led to more than 445 million infections and the underlying disease, COVID-19, resulted in more than 6 million deaths worldwide.
Franziska Ramm, Franziska Ramm, Srujan K. Dondapati, Hoai Anh Trinh, Hoai Anh Trinh, Dana Wenzel, Ruben M. Walter, Ruben M. Walter, Anne Zemella, Stefan Kubick, Stefan Kubick, Stefan Kubick   +11 more
doaj   +1 more source

Mimicry between respiratory virus proteins and some human immune proteins

Инфекция и иммунитет, 2020
A comparative analysis on search for amino acid sequences in viral proteins causing respiratory infections (or respiratory infections syndrome) homologous to amino acid sequences from some human immune proteins was performed.
I. N. Zhilinskaya
doaj   +1 more source

Steve Oroszlan: A Personal Perspective

Viruses, 2021
My memories of Steve go back over 50 years. While precise dates are no longer in my memory bank, circumstances and emotions remain alive and easy to recall.
Raymond Gilden
doaj   +1 more source

Across the Hall from Pioneers

Viruses, 2021
I was fortunate to be associated with the lab of Stephen Oroszlan at the US National Cancer Institute from ~1982 until his conversion to Emeritus status in 1995.
Alan Rein
doaj   +1 more source

Viral membrane proteins [PDF]

European Biophysics Journal, 2009
This special issue on ‘Viral membrane proteins’ incorporates a series of research articles that were presented at the ‘Conference on Viral Membrane Proteins’, held at the University of Heidelberg, Germany, on 12–14 December 2008. The aim of the symposium was to involve all areas of research in this emerging Weld focusing on biophysical and clinically ...
Wolfgang B. Fischer, Gerhard Thiel, Rainer H. A. Fink   +2 more
openaire   +1 more source

Activation of Host Cellular Signaling and Mechanism of Enterovirus 71 Viral Proteins Associated with Hand, Foot and Mouth Disease

Viruses, 2022
Enteroviruses are members of the Picornaviridae family consisting of human enterovirus groups A, B, C, and D as well as nonhuman enteroviruses. Human enterovirus type 71 (EV71) has emerged as a major cause of viral encephalitis, known as hand, foot, and ...
Subrat Kumar Swain, Subhasmita Panda, Basanta Pravas Sahu, Rachita Sarangi   +3 more
doaj   +1 more source