Results 21 to 30 of about 6,360,309 (211)

Viral proteins as a potential driver of histone depletion in dinoflagellates

open access: yesNature Communications, 2018
Within canonical eukaryotic nuclei, DNA is packaged with highly conserved histone proteins into nucleosomes, which facilitate DNA condensation and contribute to genomic regulation.
N. Irwin   +7 more
semanticscholar   +1 more source

Mapping the phosphoproteome of influenza A and B viruses by mass spectrometry [PDF]

open access: yes, 2012
Protein phosphorylation is a common post-translational modification in eukaryotic cells and has a wide range of functional effects. Here, we used mass spectrometry to search for phosphorylated residues in all the proteins of influenza A and B viruses ...
Hutchinson, Edward C.   +8 more
core   +3 more sources

Phylogeography, Transmission, and Viral Proteins of Nipah Virus

open access: yesVirologica Sinica, 2018
Nipah virus (NiV), a zoonotic paramyxovirus belonging to the genus Henipavirus, is classified as a Biosafety Level-4 pathogen based on its high pathogenicity in humans and the lack of available vaccines or therapeutics.
B. Sun   +4 more
semanticscholar   +1 more source

Proteomic and functional analyses of the virion transmembrane proteome of cyprinid herpesvirus 3 [PDF]

open access: yes, 2017
Virion transmembrane proteins (VTPs) mediate key functions in the herpesvirus infectious cycle. Cyprinid herpesvirus 3 (CyHV-3) is the archetype of fish alloherpesviruses. The present study was devoted to CyHV-3 VTPs.
Boutier, Maxime   +12 more
core   +1 more source

Towards peptide vaccines against Zika virus: Immunoinformatics combined with molecular dynamics simulations to predict antigenic epitopes of Zika viral proteins

open access: yesScientific Reports, 2016
The recent outbreak of Zika virus (ZIKV) infection in Brazil has developed to a global health concern due to its likely association with birth defects (primary microcephaly) and neurological complications. Consequently, there is an urgent need to develop
Muhammad Usman Mirza   +7 more
semanticscholar   +1 more source

Upstream-binding factor is sequestered into herpes simplex virus type 1 replication compartments [PDF]

open access: yes, 2009
Previous reports have shown that adenovirus recruits nucleolar protein upstream-binding factor (UBF) into adenovirus DNA replication centres. Here, we report that despite having a different mode of viral DNA replication, herpes simplex virus type 1 (HSV ...
Ahmed   +25 more
core   +2 more sources

Development of a minigenome cassette for Lettuce necrotic yellows virus: A first step in rescuing a plant cytorhabdovirus [PDF]

open access: yes, 2020
Rhabdoviruses are enveloped negative-sense RNA viruses that have numerous biotechnological applications. However, recovering plant rhabdoviruses from cDNA remains difficult due to technical difficulties such as the need for concurrent in planta ...
Drake, P   +3 more
core   +1 more source

Infectious Bursal Disease Virus-Host Interactions: Multifunctional Viral Proteins that Perform Multiple and Differing Jobs

open access: yesInternational Journal of Molecular Sciences, 2017
Infectious bursal disease (IBD) is an acute, highly contagious and immunosuppressive poultry disease caused by IBD virus (IBDV). The consequent immunosuppression increases susceptibility to other infectious diseases and the risk of subsequent vaccination
Yao Qin, Shijun J. Zheng
semanticscholar   +1 more source

Equine herpesvirus 1 bridles T lymphocytes to reach its target organs [PDF]

open access: yes, 2019
Equine herpesvirus 1 (EHV1) replicates in the respiratory epithelium and disseminates through the body via a cell-associated viremia in leukocytes, despite the presence of neutralizing antibodies. "Hijacked" leukocytes, previously identified as monocytic
Azab, Walid   +7 more
core   +1 more source

Influenza B virus non-structural protein 1 counteracts ISG15 antiviral activity by sequestering ISGylated viral proteins

open access: yesNature Communications, 2016
The ubiquitin-like protein ISG15 and its conjugation to proteins (ISGylation) are strongly induced by type I interferon. Influenza B virus encodes non-structural protein 1 (NS1B) that binds human ISG15 and provides an appropriate model for determining ...
Chen Zhao   +5 more
semanticscholar   +1 more source

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