Results 31 to 40 of about 928,330 (381)
I was fortunate to be associated with the lab of Stephen Oroszlan at the US National Cancer Institute from ~1982 until his conversion to Emeritus status in 1995.
Alan Rein
doaj +1 more source
Keratinocyte differentiation-dependent human papillomavirus gene regulation [PDF]
Human papillomaviruses (HPVs) cause diseases ranging from benign warts to invasive cancers. HPVs infect epithelial cells and their replication cycle is tightly linked with the differentiation process of the infected keratinocyte.
Graham, Sheila V.
core +1 more source
Assembly of Viral Membrane Proteins [PDF]
The generation of computational models is an alternative route to obtain reliable structures for the oligomeric state of membrane proteins. A strategy has been developed to search the conformational space of all possible assemblies in a reasonable time, taking symmetry considerations into account. The methodology tested on M2 from influenza A, shows an
Wolfgang B. Fischer, Jens Krüger
openaire +3 more sources
To explore the sequence context-dependent nature of the human immunodeficiency virus type 1 (HIV-1) protease’s specificity and to provide a rationale for viral mutagenesis to study the potential role of the nucleocapsid (NC) processing in HIV-1 ...
János András Mótyán+3 more
doaj +1 more source
Identification of Epstein-Barr virus replication proteins in Burkitt’s lymphoma cells [PDF]
The working model to describe the mechanisms used to replicate the cancer-associated virus Epstein-Barr virus (EBV) is partly derived from comparisons with other members of the Herpes virus family.
Almohammad, Rajei+8 more
core +2 more sources
Control of human papillomavirus gene expression by alternative splicing [PDF]
Human papillomaviruses possess circular double stranded DNA genomes of around 8 kb in size from which multiple mRNAs are synthesized during an infectious life cycle.
Faizo, Arwa Ali A., Graham, Sheila
core +1 more source
Identification of compounds with anti-human cytomegalovirus activity that inhibit production of IE2 proteins [PDF]
Using a high throughput screening methodology we surveyed a collection of largely uncharacterized validated or suspected kinase inhibitors for anti-human cytomegalovirus (HCMV) activity.
Beelontally, Rooksarr+10 more
core +2 more sources
Molecular mimicry, genetic homology, and gene sharing proteomic “molecular fingerprints” using an EBV (Epstein-Barr virus)-derived microarray as a potential diagnostic method in autoimmune disease [PDF]
EBV (Epstein-Barr Virus) and other human DNA viruses are associated with autoimmune syndromes in epidemiologic studies. In this work, immunoglobulin G response to EBV-encoded proteins which share regions with human immune response proteins from the human
Alessandra Farina, Giuseppina+2 more
core +1 more source
Unconventional secretion of viral proteins
Although largely less numerous and characterized than bacterial secreted effectors, several viral virulence factors are secreted by virus infected cells. However, their mode of secretion only starts to be studied at the molecular level. Several of these viral effectors are secreted using an unconventional secretion pathway, i.e.
Schatz, Malvina+2 more
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Role of electrostatic interactions in the assembly of empty spherical viral capsids [PDF]
We examine the role of electrostatic interactions in the assembly of empty spherical viral capsids. The charges on the protein subunits that make the viral capsid mutually interact and are expected to yield electrostatic repulsion acting against the assembly of capsids.
arxiv +1 more source