Results 161 to 170 of about 617,233 (366)
This review highlights emerging bioengineering strategies for treating neointimal hyperplasia in the peripheral vasculature, focusing on approaches that promote re‐endothelialization, modulate smooth muscle cell phenotype, reduce inflammation, mitigate oxidative stress, and optimize biomechanical compliance.
Nikita Wilson John+5 more
wiley +1 more source
Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq+4 more
wiley +1 more source
Replication of Mengovirus II. General Properties of the Viral-Induced Ribonucleic Acid Polymerase [PDF]
Peter G.W. Plagemann, H. E. Swim
openalex +1 more source
Narrow escape to small windows on a small ball modeling the viral entry into the cell nucleus [PDF]
A certain class of viruses replicates inside a cell if they can enter the nucleus through one of many small target pores, before being permanently trapped or degraded. We adopt for viral motion a switching stochastic process model and we estimate here the probability and the conditional mean first passage time for a viral particle to attain alive the ...
arxiv
This review highlights recent advances in microfluidic technologies for modeling human aging and age‐related diseases. It explores how organ‐on‐chip platforms improve physiological relevance, enable rejuvenation strategies, facilitate drug screening, detect senescent cells, and identify biomarkers.
Limor Zwi‐Dantsis+5 more
wiley +1 more source
Direct participation of a host protein in the replication of viral RNA in vitro. [PDF]
T.S. Eikhom, D J Stockley, S. Spiegelman
openalex +1 more source
G-quadruplex as an essential structural element in cytomegalovirus replication origin
G-quadruplex (G4) structures are found in eukaryotic cell replication origins, but their role in origin function remains unclear. In this study G4 motifs are found in the lytic DNA replication origin (oriLyt) of human cytomegalovirus (HCMV) and ...
Daegyu Park+7 more
doaj +1 more source
Detection of viral replication in bees
Recently foraging bees were discovered with pollen loads infected with honey bee viruses uncorrelated with the infection status of the bees itself. This observation has wide implications on the broadly used PCR viral detection techniques. False positives results could be obtained if viral remnants from infected pollen in the bee gut are detected ...
Ivan Meeus+2 more
openaire +3 more sources
This work explores the MOF landscape to select a single, optimal candidate for successfully delivering cancer drugs (gemcitabine, paclitaxel, SN‐38) into tough pancreatic tumors. Machine learning and simulations guide this search, demonstrating colloidal stability, excellent biocompatibility, cellular uptake, and sustained release.
Francesca Melle+9 more
wiley +1 more source
Effect of actinomycin D and guanidine on the formation of a ribonucleic acid polymerase induced by foot-and-mouth-disease virus and on the replication of virus and viral ribonucleic acid [PDF]
D. N. Black, F. Brown
openalex +1 more source