Seneca Valley virus infection exploits DNA damage response to facilitate viral replication. [PDF]
Song J+7 more
europepmc +1 more source
The vpx gene of simian immunodeficiency virus facilitates efficient viral replication in fresh lymphocytes and macrophage [PDF]
Xiaotian Yu, Q C Yu, Max Essex, T H Lee
openalex +1 more source
An Agrin–YAP/TAZ Rigidity Sensing Module Drives EGFR‐Addicted Lung Tumorigenesis
The study identifies agrin‐EGFR mechanotransduction as a critical driver of lung adenocarcinoma which enhances EGFR signaling through an integrin‐FAK‐actomyosin dependent positive feedback on YAP/TAZ ‐TEAD in response to matrix stiffness. Targeting this oncogenic loop through combinatorial treatments inhibits lung cancer due to agrin impairment.
Reza Bayat Mokhtari+20 more
wiley +1 more source
Reduction of microRNA-221 in BVDV infection enhances viral replication by targeting the ATG7-mediated autophagy pathway. [PDF]
Chen Z+12 more
europepmc +1 more source
Mechanisms of viral pathogenesis. Distinct forms of reoviruses and their roles during replication in cells and host. [PDF]
Max L. Nibert+2 more
openalex +1 more source
In KLF1‐on (neonatal and Klf1 overexpression hearts) models, KLF1 regulates Wnt/β‐catenin signaling pathway and the expression of cell proliferation‐related genes via transcriptional and epigenetic mechanisms, which induces cardiomyocyte proliferation and cardiac regeneration in mice after myocardial infarction.
Yanglin Hao+19 more
wiley +1 more source
Absence of Viral Replication Is Associated With Improved Outcome in Anti-HCV-Positive Patients With Hepatocellular Carcinoma. [PDF]
Giannini EG+30 more
europepmc +1 more source
Detecting the ability of viral, bacterial and eukaryotic replication proteins to track along DNA. [PDF]
Rachel L. Tinker+2 more
openalex +1 more source