Results 191 to 200 of about 366,840 (272)

Confinement by Liquid‐Liquid Interface Replicates In Vivo Neutrophil Deformations and Elicits Bleb‐Based Migration

Advanced Science, EarlyView.
Leukocytes sense mechanical cues provided by surrounding cells to regulate motility. Replicating the confining pressures applied by soft, elastic tissues in vitro is challenging. Here, the use of liquid‐liquid interfaces is introduced to model forces exerted by surrounding cells. Confining pressures are tunable by controlling interfacial curvature, and
Jonathan H. Schrope, Adam Horn, Kaitlyn Lazorchak, Clyde W. Tinnen, Jack J Stevens, Mehtab Farooqui, Tanner Robertson, Jiayi Li, David Bennin, Terry Juang, Adeel Ahmed, Chao Li, Anna Huttenlocher, David J Beebe   +13 more
wiley   +1 more source

Foot-and-mouth disease virus activates glycolysis and hijacks HK2 to inhibit innate immunity and promote viral replication. [PDF]

Vet Res
Chen W, Wang X, Li X, Wang W, Huang Y, Qin Y, Liu P, Wu K, Li B, He Y, Zeng S, Yi L, Wang L, Zhao M, Ding H, Fan S, Li Z, Chen J.   +17 more
europepmc   +1 more source

Tumor‐Adhesive Chitosan‐Derived Multi‐Immune Agonist Unleashes Strong and Durable Anti‐Cancer Immunity

Advanced Science, EarlyView.
A tumor‐adhesive chitosan‐derived immune agonist TACTIC is developed for strong and durable anti‐tumor immunity. The immune agonist exhibits multi‐targets and modulates both tumor cell immunogenicity and pro‐inflammatory responses in immune cells, thereby potentiating the therapeutic efficacy of clinical radiotherapy.
Huilan He, Liang Liu, Yun Zheng, Jinlong Ji, Li Cao, Chunlian Ye, Yu Sun, Ying Zhang, Zhiyuan Zhong   +8 more
wiley   +1 more source

Human alpha-herpesvirus 1 (HSV-1) viral replication and reactivation from latency are expedited by the glucocorticoid receptor. [PDF]

J Virol
Jones C.
europepmc   +1 more source

Relationship between frequency of infectious human immunodeficiency virus type 1-harboring cells and kinetics of viral replication: a simple procedure for quantitation of infectious virus-carrying cells in blood samples [PDF]

, 1992
Wei Lu, G Manolikakis, Jean‐Marie Andrieu   +2 more
openalex   +1 more source

ADAR1‐HNRNPL‐Mediated CircCANX Decline Promotes Autophagy in Chronic Obstructive Pulmonary Disease

Advanced Science, EarlyView.
ADAR1‐HNRNPL interaction‐repressed circCANX recruits P53 mRNA and UPF1 to assemble a complex in nuclear. This complex promotes P53 mRNA degradation through the NMD pathway, and finally reduces autophagy and stress granules formation to further regulate inflammation.
Ting‐Ting Chen, Yuan‐Yuan Wei, Jia‐Ying Kang, Da‐Wei Zhang, Jing‐Jing Ye, Xi‐Shi Sun, Mei Hong, Wen‐Ting Zhang, Hui‐Mei Wu, Zhen‐Xing Ding, Guang‐He Fei   +10 more
wiley   +1 more source

YBX1 is required for assembly of viral replication complexes of chikungunya virus and replication of multiple alphaviruses. [PDF]

J Virol
Li Z-Q, Zhao L-X, Wang S-Y, Hu C-Y, Wang Y-Y, Yang Y.   +5 more
europepmc   +1 more source

Conserved cysteine and histidine residues of the avian myeloblastosis virus nucleocapsid protein are essential for viral replication but are not "zinc-binding fingers".

, 1988
Joyce E. Jentoft, L Smith, Xiangdong Fu, Martin R. Johnson, Jonathan Leis   +4 more
openalex   +1 more source

A Model of Epigenetic Inheritance Accounts for Unexpected Adaptation to Unforeseen Challenges

Advanced Science, EarlyView.
A general model of inheriting changes that are acquired during the lifetime of individuals demonstrates tremendous benefits to the population, including escape from extinction in changing environments. Contrasting the model with experimental data shows that inheritance of acquired changes enables rapid adaptation to unforeseen challenges, and accounts ...
Dino Osmanović, Yitzhak Rabin, Yoav Soen   +2 more
wiley   +1 more source

Synthesis of parvovirus H-1 replicative form from viral DNA by DNA polymerase gamma.

, 1981
Regine Kollek, Mehran Goulian
openalex   +1 more source