Results 211 to 220 of about 366,840 (272)

Catheter Injectable Multifunctional Biomaterial for the Treatment of Infected Enterocutaneous Fistulas

Advanced Science, EarlyView.
A multi‐functional shear‐thinning hydrogel is engineered to treat enterocutaneous fistulas. This hydrogel can resist external pressures allowing it to remain within the fistula tract and is shown to have significant antimicrobial, pro‐healing, and anti‐inflammatory properties, which were validated in in vitro and in vivo experiments.
Jinjoo Kim, Zefu Zhang, Hassan Albadawi, Hyeongseop Keum, Joseph L. Mayer, Erin H. Graf, Rahmi Oklu   +6 more
wiley   +1 more source

Perturbation of <i>de novo</i> lipogenesis hinders MERS-CoV assembly and release, but not the biogenesis of viral replication organelles. [PDF]

J Virol
Soultsioti M, de Jong AWM, Blomberg N, Tas A, Giera M, Snijder EJ, Bárcena M.   +6 more
europepmc   +1 more source

Nuclear Translocation of S100A9 Triggers Senescence of Human Amnion Fibroblasts by De‐Repressing LINE1 Via Heterochromatin Erosion at Parturition

Advanced Science, EarlyView.
This study shows that the classical secretory protein S100 calcium‐binding protein A9 (S100A9) can translocate to the nucleus upon de‐phosphorylation at Thr 113 in human amnion fibroblasts at parturition, where S100A9 induces heterochromatin erosion through segregation of the heterochromatin maintenance protein, resulting inLong Interspersed Nuclear ...
Fan Zhang, Meng‐Die Li, Fan Pan, Wen‐Jia Lei, Yang Xi, Li‐Jun Ling, Leslie Myatt, Kang Sun, Wang‐Sheng Wang   +8 more
wiley   +1 more source

RNA Helicase DDX3 Interacts with the Capsid Protein of Hepatitis E Virus and Plays a Vital Role in the Viral Replication. [PDF]

Pathogens
Lin S, Sallapalli BT, Chang P, He J, Coyaud E, Pierce BG, Zhang YJ.   +6 more
europepmc   +1 more source

A synthetic peptide inhibitor of human immunodeficiency virus replication: correlation between solution structure and viral inhibition.

, 1992
Carl Wild, Terrence G. Oas, Charlene McDanal, Dani P. Bolognesi, Thomas J. Matthews   +4 more
openalex   +1 more source

Altered Neural Activity in the Mesoaccumbens Pathway Underlies Impaired Social Reward Processing in Shank3‐Deficient Rats

Advanced Science, EarlyView.
This study examines the effects of Shank3 mutation on the mesoaccumbens pathway using a Shank3‐deficient rat model. The findings reveal altered social reward processing in these rats, accompanied by changes in dopaminergic and GABAergic neural activity within the ventral tegmental area (VTA) and dopamine release in the nucleus accumbense (NAc ...
Marie Barbier, Keerthi Thirtamara Rajamani, Shai Netser, Shlomo Wagner, Hala Harony‐Nicolas   +4 more
wiley   +1 more source

BEV 2C protein inhibits the NF-κB signalling pathway to promote viral replication by targeting IKBKB and p65. [PDF]

Vet Res
Cui X, Guo Y, Zhang F, Chang X, Hu J, Zhang Q, Zheng X, Yan N, Wang X.   +8 more
europepmc   +1 more source

Replicational release of geminivirus genomes from tandemly repeated copies: evidence for rolling-circle replication of a plant viral DNA.

, 1991
Drake C. Stenger, G N Revington, M C Stevenson, David M. Bisaro   +3 more
openalex   +1 more source

Inhibiting the Histone Demethylase Kdm4a Restrains Cardiac Fibrosis After Myocardial Infarction by Promoting Autophagy in Premature Senescent Fibroblasts

Advanced Science, EarlyView.
Kdm4a downregulation restrains excessive cardiac interstitial fibrosis and remodeling by depressing the premature senescence of fibroblasts in the advanced stage after MI but does not affect early ventricular rupture. It verified that Kdm4a downregulation promotes autophagy in premature senescent fibroblasts by increasing the H3K9m3 modification of the
Ming Jin, Chuling Li, Zhaoyi Wu, Zhenquan Tang, Jingfang Xie, Guoquan Wei, Zhiwen Yang, Senlin Huang, Yijin Chen, Xinzhong Li, Yanmei Chen, Wangjun Liao, Yulin Liao, Guojun Chen, Hao Zheng, Jianping Bin   +15 more
wiley   +1 more source

The Japanese encephalitis virus NS1 protein concentrates ER membranes in a cytoskeleton-independent manner to facilitate viral replication. [PDF]

J Virol
Xie S, Lin X, Yang Q, Shi M, Yang X, Cao Z, Cao R.   +6 more
europepmc   +1 more source