Results 221 to 230 of about 2,261,873 (405)

Highly Tunable and Cell‐Remodelable Thiol‐ene Alginate‐Peptide Crosslinked Hydrogels to Recreate Cellular and Organoid Microenvironments for Biofabrication

Advanced Healthcare Materials, EarlyView.
Norbornene‐functionalized alginate is crosslinked with a di‐thiolated peptide sequence cleavable by cell‐secreted matrix metalloproteinases and decorated with cell‐adhesion peptides upon exposure to UV. Thyroid follicles, endometrial and intestinal organoids are encapsulated in a gentle manner with high cell viability and correct phenotype ...
Julia Fernández‐Pérez, Adrián Seijas‐Gamardo, Antonio J. Feliciano, Panagiota Kakni, Anna M. Kip, Paul Wieringa, Stefan Giselbrecht, Matthew B. Baker, Lorenzo Moroni   +8 more
wiley   +1 more source

Activation of the PI3K/Akt Pathway Early during Vaccinia and Cowpox Virus Infections Is Required for both Host Survival and Viral Replication

, 2009
Jamária A. P. Soares, Flávia G. G. Leite, Luciana Garcia Andrade, Alice A. Torres, Lirlândia P. Sousa, Lucíola S. Barcelos, Mauro Martins Teixeira, Paulo César Peregrino Ferreira, Erna Geessien Kroon, Thaïs Souto-Padrón, Cláudio Antônio Bonjardim   +10 more
openalex   +2 more sources

Rational Design of Metal–Organic Frameworks for Pancreatic Cancer Therapy: from Machine Learning Screening to In Vivo Efficacy

Advanced Materials, EarlyView.
This work explores the MOF landscape to select a single, optimal candidate for successfully delivering cancer drugs (gemcitabine, paclitaxel, SN‐38) into tough pancreatic tumors. Machine learning and simulations guide this search, demonstrating colloidal stability, excellent biocompatibility, cellular uptake, and sustained release.
Francesca Melle, Dhruv Menon, João Conniot, Jon Ostolaza‐Paraiso, Sergio Mercado, Jhenifer Oliveira, Xu Chen, Bárbara B. Mendes, João Conde, David Fairen‐Jimenez   +9 more
wiley   +1 more source

Heat Shock Protein 90 Positively Regulates Chikungunya Virus Replication by Stabilizing Viral Non-Structural Protein nsP2 during Infection

, 2014
Indrani Das, Itishree Basantray, Prabhudutta Mamidi, Tapas Kumar Nayak, B.M. Pratheek, Subhasis Chattopadhyay, Soma Chattopadhyay   +6 more
openalex   +2 more sources

Divide et Impera: An In Silico Screening Targeting HCMV ppUL44 Processivity Factor Homodimerization Identifies Small Molecules Inhibiting Viral Replication

, 2020
Hanieh Ghassabian, Federico Falchi, Martina Timmoneri, Beatrice Mercorelli, Arianna Loregian, Giorgio Palù, Gualtiero Alvisi   +6 more
openalex   +2 more sources

Relationship between frequency of infectious human immunodeficiency virus type 1-harboring cells and kinetics of viral replication: a simple procedure for quantitation of infectious virus-carrying cells in blood samples [PDF]

, 1992
Wei Lu, G Manolikakis, Jean‐Marie Andrieu   +2 more
openalex   +1 more source

Carbon Quantum Dots Assisted Virus Tracking: From Skin to Brain

Advanced Materials, EarlyView.
A novel carbon quantum dots‐dissolvable microneedle, CQDs‐dMN system, enables painless delivery and real‐time tracking of HSV‐1. The HSV‐1 is labeled with fluorescent CQDs and delivered to the skin dermis, minimizing damage compared to traditional methods.
Yaxiu Feng, Xiong Wang, Cien Chen, Di Wang, Changshun Hou, Yiran Wang, Huan Hu, Peiran Chen, LeiYing Qin, Qianya Wan, Xi Yao, Ming‐Liang He   +11 more
wiley   +1 more source

Iron limitation differentially affects viral replication in key marine microbes. [PDF]

Proc Natl Acad Sci U S A
Yung CCM, Kelly RL, Kauffman KM, Cunningham BR, Zimmerman AE, Worden AZ, John SG.   +6 more
europepmc   +1 more source

PolyC-Binding Protein 1 Interacts with 5′-Untranslated Region of Enterovirus 71 RNA in Membrane-Associated Complex to Facilitate Viral Replication

, 2014
Zhen Luo, Xingchen Dong, Youxing Li, Qi Zhang, Chol-Ho Kim, Yu Song, Lei Kang, Yingle Liu, Kailang Wu, Jianguo Wu   +9 more
openalex   +2 more sources

Phosphorylation of Hepatitis C Virus RNA Polymerases Ser29 and Ser42 by Protein Kinase C-Related Kinase 2 Regulates Viral RNA Replication [PDF]

, 2014
Song-Hee Han, Seong-Jun Kim, Eun‐Jung Kim, Tae-Eun Kim, Jae-Su Moon, Geon‐Woo Kim, Seung‐Hoon Lee, Kun Cho, Jong Shin Yoo, Woo Sung Son, Jin‐Kyu Rhee, Seung Hyun Han, Jong‐Won Oh   +12 more
openalex   +1 more source