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Advanced Science, EarlyView.TIPE1m NPs nanoparticles restore TIPE1 expression, promote RAB7A ubiquitination and degradation, suppress autophagic flux, and resensitize paclitaxel‐resistant triple‐negative breast cancer to therapy. ABSTRACT Acquired paclitaxel (PTX) resistance remains a major obstacle in triple‐negative breast cancer (TNBC) treatment.
Wei Hu +9 more
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Polymer Concepts in Cellular Function
Advanced Science, EarlyView.
Miao Yu +7 more
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Studies in the replication of viral RNA
Journal of Cellular Physiology, 1967Experiments will be described which demonstrate that the product of purified “Qβ-replicase” is fully competent to serve both as a template and as a program for the synthesis of complete virus particles. The use of mutant RNA has permitted the demonstration that nucleic acid is the instructive agent in the replication process and hence satisfies the ...
S, Spiegelman +6 more
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Viral replication in mouse macrophages
Archiv f�r die gesamte Virusforschung, 1972Cultures of mouse peritoneal macrophages were capable of supporting the growth of vesicular stomatitis virus (VSV), mengovirus, mouse hepatitis virus (MHV-3 and MHV-S), and reovirus type 3. Age of the cultures and peritoneal stimulation of macrophages appeared to influence this capacity.
J M, Eustatia +3 more
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MicroRNAs in Viral Replication and Pathogenesis
DNA and Cell Biology, 2007MicroRNAs (miRNAs) are an important class of small, noncoding, regulatory RNAs found to be involved in regulating a wide variety of important cellular processes by the sequence-specific inhibition of gene expression. Viruses have evolved a number of mechanisms to take advantage of the regulatory potential of this highly conserved, ubiquitous pathway ...
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Initiation of Viral DNA Replication
1988Publisher Summary This chapter focuses on the mechanisms involved in initiation of animal virus DNA replication. This step is of fundamental importance because it represents the central point of control of the replication process. Two of the best-characterized viruses, adenovirus and SV40, are discussed as examples of viruses that normally multiply ...
T J, Kelly, M S, Wold, J, Li
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Oxygen Biology and Viral Replication.
Virologie (Montrouge, France), 2014International ...
Morinet, Frédéric, Pillet, Sylvie
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Viral replication and genetics
2016This chapter argues that viruses are at a major disadvantage in the task of reproducing themselves compared with higher forms of life. The latter all multiply by some form of fission, which ensures that the daughter cells start their existence with a full complement of genetic information, along with the enzymes necessary to replicate and catalyse the ...
John Oxford, Paul Kellam, Leslie Collier
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La Revue du praticien, 1997
The multiplication of viruses depends on the virus and the infected cell. Viruses seem to have evolved by several routes and no single pattern of replication has prevailed. The cells can be permissive with productive infection or not. The productive cycle of viruses infecting eukaryotic cells exhibit several common steps.
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The multiplication of viruses depends on the virus and the infected cell. Viruses seem to have evolved by several routes and no single pattern of replication has prevailed. The cells can be permissive with productive infection or not. The productive cycle of viruses infecting eukaryotic cells exhibit several common steps.
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1993
Abstract During the last decade considerable interest has focused upon the mechanisms by which the genomes of DNA animal viruses are replicated. These studies provide information relevant not only to our understanding of viral growth and potential strategies for intervention, but also to processes occurring during the replication of ...
Nigel D Stow, Ronald T Hay
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Abstract During the last decade considerable interest has focused upon the mechanisms by which the genomes of DNA animal viruses are replicated. These studies provide information relevant not only to our understanding of viral growth and potential strategies for intervention, but also to processes occurring during the replication of ...
Nigel D Stow, Ronald T Hay
openaire +1 more source