Results 311 to 320 of about 2,155,361 (380)

Classical swine fever virus utilizes stearoyl-CoA desaturase 1-mediated lipid metabolism to facilitate viral replication. [PDF]

J Virol
Bai J-s, Zou L-K, Liu Y-Y, Zhong L-H, Chen J, Chen J-X, Zhao B-Q, Liu R-C, Sun B-T, Zhou B.   +9 more
europepmc   +1 more source

Activation of Lysosomal Retrograde Transport Triggers TPC1‐IP3R1 Ca2+ Crosstalk at Lysosome‐ER MCSs Leading to Lethal Depleting of ER Calcium

Advanced Science, EarlyView.
The flavonoid compound LW‐213 exerts its antitumor effects through a novel mechanism involving lysosomal‐ER calcium regulation. Specifically, LW‐213 binds to LIMP2, which induces perinuclear clustering of lysosomes and facilitates calcium‐mediated lysosome‐ER interactions.
Meng‐yuan Zhu, Yong‐jian Guo, Yu‐qi Zhu, Hong‐zheng Wang, Hai‐di Wang, Hong‐yu Chen, Yue‐xin Jiang, Hui Li, Hui Hui   +8 more
wiley   +1 more source

Spring viraemia of carp virus modulates the time-dependent unfolded protein response to facilitate viral replication. [PDF]

Front Immunol
Romero A, Figueras A, Novoa B.
europepmc   +1 more source

Dengue Virus Inhibition of Autophagic Flux and Dependency of Viral Replication on Proteasomal Degradation of the Autophagy Receptor p62

Journal of Virology, 2015
P. Metz, Abhilash I. Chiramel, Laurent Chatel-Chaix, G. Alvisi, P. Bankhead, R. Mora-Rodríguez, G. Long, A. Hamacher-Brady, N. Brady, R. Bartenschlager   +9 more
semanticscholar   +1 more source

Systematic Targeting of GD2‐Positive Neuroblastoma Tumors With a Photooncolytic Phage Nanovector Platform

Advanced Science, EarlyView.
A tumor‐penetrating photooncolytic phage is developed for selectively targeting and delivering photosensitizers to GD2‐positive Neuroblastoma cells. Upon light activation, it precisely induces oncolysis of GD2‐positive cells with no effect on GD2‐negative ones.
Suleman Khan Zadran, Nicola Facchinello, Piergiuseppe De Rosa, Roberto Saporetti, Paolo Emidio Costantini, Luca Ulfo, Michela Nigro, Annapaola Petrosino, Lucia Pappagallo, Sara Aloisi, Giorgio Milazzo, Zainul Abe Din, Alberto Rigamonti, Leonardo Flora, Martina Santulli, Leonardo Cimadom, Giampaolo Zuccheri, Mattia Zangoli, Manuele Di Sante, Matteo Di Giosia, Francesca Di Maria, Roberto Bernardoni, Eveline Barbieri, Matteo Calvaresi, Alberto Danielli, Giovanni Perini   +25 more
wiley   +1 more source

Cell-intrinsic regulation of HBV RNAs by the nonsense-mediated mRNA decay pathway controls viral replication. [PDF]

iScience
Wada M, Morita C, Ohsaki E, Ueda K.
europepmc   +1 more source

Phosphorylation-dependent interaction of adenovirus preterminal protein with the viral origin of DNA replication.

, 1994
Jingo Kusukawa, Murali Ramachandra, Ryuichi Nakano, R. Padmanabhan   +3 more
openalex   +1 more source

Enhanced Activities of OCT4 and SOX2 Promote Epigenetic Reprogramming by Shortening G1 Phase

Advanced Science, EarlyView.
Fusing the VP16 domain to OCT4 and SOX2 (OvSvK) enhances iPSC generation by activating downstream targets, including those regulating the cell cycle. This accelerates reprogramming by shortening the G1 phase and reducing H3K27me3 levels. Modulating Ccnd1, Cdkn2a, and Ccne1 improves efficiency, linking cell cycle to epigenetic remodeling.
Lin Guo, Jiechun Lin, Qiwen Ren, Hao Sun, Yanhua Wu, Haofei Ge, Xiaolan Wu, Lihui Lin, Lining Liang, Changpeng Li, He Liu, Yuangbang Mai, Shilong Chu, Jiadong Liu, Jing Liu, Jiekai Chen, Duanqing Pei, Hui Zheng   +17 more
wiley   +1 more source

Reduction of microRNA-221 in BVDV infection enhances viral replication by targeting the ATG7-mediated autophagy pathway. [PDF]

Ir Vet J
Chen Z, Wang J, Lu B, Meng W, Zhu Y, Jiang Q, Gao D, Ma Z, Zeng H, Chen J, Liu S, Wang Z, Jia K.   +12 more
europepmc   +1 more source

O⁶-methylguanine in the SV40 origin of replication inhibits binding but increases unwinding by viral large T antigen

, 1990
Margherita Bignami, David P. Lane
openalex   +2 more sources