Results 241 to 250 of about 956,535 (302)

Assessment of viral pathogen removal across wastewater treatment stages in a swine processing facility

Australian Veterinary Journal, EarlyView.
A swine abattoir wastewater treatment system in Queensland, Australia, was monitored over 6 months to assess the effectiveness of a pond‐based treatment system for the removal of viruses prior to irrigation reuse. Four viruses were tracked through the facility, from points of entry to the final treated effluent, to identify major sources of viral ...
W Ahmed, M Gebrewold, WJM Smith, K Richards, SL Simpson   +4 more
wiley   +1 more source

Large-scale silane bead-based SARS-CoV-2 testing of a nursing home in Spain identifies a viral reservoir during lockdown period

, 2021
Weber ND, Goñi-Salaverri A, Rodríguez JA, Unfried JP, Alameda D, Fernández-Alonso M, Sáez E, Maestro-Galilea S, Alegre F, Carmona-Torre F, Marin-Oto M, Olagüe C, Odriozola L, Navarro-Alonso M, Sanchez-Ostiz R, Argemi J, Pozo JLd, Lara-Astiaso D.   +17 more
europepmc   +1 more source

Selective excitatory effects of γ‐glutamyl‐glycine, a glutathione metabolite, on GluN1 NMDA and mGlu5 receptors impacting synaptic plasticity

British Journal of Pharmacology, EarlyView.
Background and Purpose Gamma‐glutamyl dipeptides are essentially produced after glutathione (GSH) degradation. While several γ‐glutamyl dipeptides have been detected in different organs and body fluids, their biological activity remains elusive. This is the case for γ‐Glutamyl‐Glycine (γ‐Glu‐Gly) which has been found in different brain areas.
Sandro Andreu, Victoria Gizzi, Ugo Pasco, Fatiha Sebih, Yattou Zitouni, Pablo Jimenez, Valérie Rolland, Alain Chavanieu, Sébastien Estaran, Matthieu Rousset, Thierry Cens, Guillaume Cazals, Pierre Charnet, Janique Guiramand, Catherine Cohen‐Solal, Claudine Ménard, Marie‐Céleste de Jésus Ferreira, Nathalie Chevallier, Sonia Cantel, Michel Vignes, Julien Roussel   +20 more
wiley   +1 more source

Early antiretroviral therapy in neonates with HIV-1 infection restricts viral reservoir size and induces a distinct innate immune profile. [PDF]

Sci Transl Med, 2019
Garcia-Broncano P, Maddali S, Einkauf KB, Jiang C, Gao C, Chevalier J, Chowdhury FZ, Maswabi K, Ajibola G, Moyo S, Mohammed T, Ncube T, Makhema J, Jean-Philippe P, Yu XG, Powis KM, Lockman S, Kuritzkes DR, Shapiro R, Lichterfeld M.   +19 more
europepmc   +1 more source

Spatiotemporal CD8+ T‐Cell Dynamics: Clonal Replacement and Expansion as Determinants of Sustainable Antitumor Response

Cancer Science, EarlyView.
Durable antitumor immunity depends on continuous clonal replacement: immune checkpoint inhibitors that drive sustainable, polyclonal mobilization of T‐cell clones from tumor‐draining lymph nodes sustain tumor control, whereas limited, oligoclonal mobilization allows pre‐existing clones to become exhausted, leading to immune escape.
Satoshi Ueha, Hiroyasu Aoki, Munetomo Takahashi, Shigeyuki Shichino, Kouji Matsushima   +4 more
wiley   +1 more source

HIV Subtype and Nef-Mediated Immune Evasion Function Correlate with Viral Reservoir Size in Early-Treated Individuals. [PDF]

J Virol, 2019
Omondi FH, Chandrarathna S, Mujib S, Brumme CJ, Jin SW, Sudderuddin H, Miller RL, Rahimi A, Laeyendecker O, Bonner P, Yue FY, Benko E, Kovacs CM, Brockman MA, Ostrowski M, Brumme ZL.   +15 more
europepmc   +1 more source

Advances in Spatial Heterogeneity and Cellular Localization Specificity of Intratumoral Bacteria

Cancer Science, EarlyView.
Spatial localization of intratumoral bacteria governs their functional roles in tumor progression, metastasis, and treatment responses, with guiding significance for clinical management, as reviewed across three spatial paradigms. ABSTRACT Bacteria in tumors are increasingly recognized to be a part of the tumor microenvironment and their biological ...
Minlan Ren, Jing Jia, Tingting Li, Yiwei Li, Nanxiang Shen, Yun Shi, Zhe Wang, Hao Fan, Guangli Sun, Guanying Xiong, Gang Li, Rui Peng   +11 more
wiley   +1 more source

Advancing FAIR phylogenetics for health threats: a systematic review of SARS‐CoV‐2 research and guidelines for future outbreaks

Cladistics, EarlyView.
Abstract During the COVID‐19 pandemic, the need for quick public health action often conflicted with the careful methods required in phylogenetics. To explore this, we reviewed 217 SARS‐CoV‐2 studies published from January 2020 to March 2025 in 121 journals.
Omkar Marne, Denis Jacob Machado
wiley   +1 more source

Mitigating the human link in emerging reptile fungal pathogen transmission

Conservation Biology, EarlyView.
Abstract Handling wild reptiles is common among amateur herpetology enthusiasts, professional researchers, social media influencers, and photographers. However, the potential for these interactions to spread diseases that threaten wild reptiles remains underappreciated.
Patrick S. Champagne, Richelle G. Butcher, Lachlan A. Bourke, Lorenzo Seneci, Laura F. Grogan   +4 more
wiley   +1 more source

Ecological considerations for reintroducing Chinook salmon upstream of Shasta Dam

Conservation Science and Practice, EarlyView.
In this assessment, we reviewed existing literature to assess the ecological risks, benefits, and uncertainties associated with reintroducing Chinook salmon into the McCloud River, a tributary of the Sacramento River, California. We identified considerations related to population viability, disease, and species interactions.
Claire E. Couch, Bailey A. Morgan, Carl Ostberg, BayLee R. Laufer, Jan Lovy, Rachelle C. Johnson, Jill M. Hardiman, Tobias J. Kock   +7 more
wiley   +1 more source