Results 41 to 50 of about 24,194,770 (306)
Frontiers in ImmunologySimian immunodeficiency virus (SIV) vaccines based upon 68-1 Rhesus Cytomegalovirus (RhCMV) vectors show remarkable protection against pathogenic SIVmac239 challenge.
Benjamin N. Bimber +17 more
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Virseqimprover: an integrated pipeline for viral contig error correction, extension, and annotation [PDF]
PeerJDespite the recent surge of viral metagenomic studies, it remains a significant challenge to recover complete virus genomes from metagenomic data. The majority of viral contigs generated from de novo assembly programs are highly fragmented, presenting ...
Haoqiu Song +5 more
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Functional Constraint Profiling of a Viral Protein Reveals Discordance of Evolutionary Conservation and Functionality. [PDF]
PLoS Genetics, 2015 Viruses often encode proteins with multiple functions due to their compact genomes. Existing approaches to identify functional residues largely rely on sequence conservation analysis.
Nicholas C Wu +10 more
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Error correction and diversity analysis of population mixtures determined by NGS [PDF]
, 2014 The impetus for this work was the need to analyse nucleotide diversity in a viral mix taken from honeybees; the methods are illustrated using honeybee viral samples. The paper has two findings. First, a method for correction of next generation sequencing
David J Evans +13 more
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Sequence analysis of the small (s) RNA segment of viruses in the genus Orthobunyavirus [PDF]
, 2008 Viruses in the genus Orthobunyavirus (family Bunyaviridae) are classified serologically into 18 serogroups. The viruses have a tripartite genome of negative sense RNA composed of large (L), medium (M) and small (S) segments.
Mohamed, Maizan
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Applications of viral metagenomics in the veterinary field [PDF]
, 2010 Viral metagenomics provide a powerful technology to investigate the viral flora of healthy and sick animals. Using these methodologies, we gain a better understanding in the etiology of diseases, as well as deepen our knowledge into the viruses ...
Blomström, Anne-Lie
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Scientific Reports, 2021 Many lentiviral vectors used for gene therapy are derived from HIV-1. An optimal vector genome would include only the viral sequences required for transduction efficiency and gene expression to minimize the amount of foreign sequence inserted into a ...
Helin Sertkaya +5 more
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Frontiers in Cellular and Infection Microbiology, 2023 IntroductionEarly and accurate identification of pathogens is essential for improved outcomes in patients with viral encephalitis (VE) and/or viral meningitis (VM).MethodsIn our research, Metagenomic next-generation sequencing (mNGS) which can identify viral pathogens unbiasedly was performed on RNA and DNA to identify potential pathogens in ...
Yi-Long Wang +27 more
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Tomato marchitez virus, a new plant picorna-like virus from tomato related to tomato torrado virus [PDF]
, 2008 A new virus was isolated from a tomato plant from the state of Sinaloa in Mexico. This plant showed symptoms locally known as `marchitez disease¿: severe leaf necrosis, beginning at the base of the leaflets, and necrotic rings on the fruits.
Verbeek, M. +4 more
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The nucleotide sequence and genome organization of
Virology Journal, 2011 Background Only very few viruses of Oomycetes have been studied in detail. Isometric virions were found in different isolates of the oomycete Plasmopara halstedii, the downy mildew pathogen of sunflower. However, complete nucleotide sequences and data on
Göpfert Jens C +3 more
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