Results 61 to 70 of about 24,194,770 (306)

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Decreased HIV diversity after allogeneic stem cell transplantation of an HIV-1 infected patient : a case report [PDF]

, 2010
The human immunodeficiency virus type 1 (HIV-1) coreceptor use and viral evolution were analyzed in blood samples from an HIV-1 infected patient undergoing allogeneic stem cell transplantation (SCT).
Bravo Ignacio G, Wolf, Timo, Schnierle Barbara S, Schnierle, Barbara S, Thielen, A., Krause, B., Werner, A., Schnierle, Barbara, Christel Kamp, Bravo, I., Winskowsky, Gudrun, Albrecht Werner, Neumann, B., Thielen, Alexander, Werner Albrecht, Krause Birgit, Kamp Christel, Timo Wolf, Wolf, T., Thielen Alexander, Winskowsky, G., Kraus, Benjamin, Wolf Timo, Werner, Albrecht, Gudrun Winskowsky, Alexander Thielen, Neumann, Britta, Birgit Krause, Bravo, Ignacio G., Neumann Britta, Kraus, B., Kamp, Christel, Kamp, C., Ignacio G Bravo, Barbara S Schnierle, Krause, Birgit, Bravo, Ignacio G, Winskowsky Gudrun, Kraus Benjamin, Britta Neumann, Schnierle, B., Benjamin Kraus   +41 more
core   +1 more source

Association of coral algal symbionts with a diverse viral community responsive to heat shock

BMC Microbiology, 2017
Background Stony corals provide the structural foundation of coral reef ecosystems and are termed holobionts given they engage in symbioses, in particular with photosynthetic dinoflagellates of the genus Symbiodinium.
Jan D. Brüwer, Shobhit Agrawal, Yi Jin Liew, Manuel Aranda, Christian R. Voolstra   +4 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

viRome: an R package for the visualization and analysis of viral small RNA sequence datasets [PDF]

Bioinformatics, 2013
Abstract Summary: RNA interference (RNAi) is known to play an important part in defence against viruses in a range of species. Second-generation sequencing technologies allow us to assay these systems and the small RNAs that play a key role with unprecedented depth.
Mick Watson, Esther Schnettler, Alain Kohl   +2 more
openaire   +5 more sources

Genomic Analysis of Amphioxus Reveals a Wide Range of Fragments Homologous to Viral Sequences

Viruses, 2023
Amphioxus species are considered living fossils and are important in the evolutionary study of chordates and vertebrates. To explore viral homologous sequences, a high-quality annotated genome of the Beihai amphioxus (Branchiostoma belcheri beihai) was examined using virus sequence queries.
Qiao Du, Fang Peng, Qing Xiong, Kejin Xu, Kevin Yi Yang, Mingqiang Wang, Zhitian Wu, Shanying Li, Xiaorui Cheng, Xinjie Rao, Yuyouye Wang, Stephen Kwok-Wing Tsui, Xi Zeng   +12 more
openaire   +3 more sources

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Nucleotide sequence and genomic organization of an ophiovirus associated with lettuce big-vein disease [PDF]

, 2002
The complete nucleotide sequence of an ophiovirus associated with lettuce big-vein disease has been elucidated. The genome consisted of four RNA molecules of approximately 7ò8, 1ò7, 1ò5 and 1ò4 kb.
Wilk, F., van der, Dullemans, A.M., Verbeek, M., Heuvel, J.F.J.M., van den   +3 more
core  

Viral adaptation to host immune responses occurs in chronic hepatitis B virus (HBV) infection, and adaptation is greatest in HBV e antigen-negative disease [PDF]

, 2012
Hepatitis B virus (HBV)-specific T-cell responses are important in the natural history of HBV infection. The number of known HBV-specific T-cell epitopes is limited, and it is not clear whether viral evolution occurs in chronic HBV infection. We aimed to
Chopra, A., Gordon, A, Scott Bowden, Pfafferott, K, Desmond, P.V., Ian R. James, Revill, P.A., Chopra, A, Mallal, SA, Silvana Gaudieri, Anna Ayres, Lewin, S.R., Thompson, AJ, Desmond, C.P., Jennifer Audsley, James, IR, Locarnini, SA, Stephen A. Locarnini, Sharon R. Lewin, James, I.R., Locarnini, S.A., Chivers, S., Christopher P. Desmond, Desmond, PV, Thompson, A.J., Stuart K. Roberts, Audsley, J, Revill, PA, Lau, GK, Gaudieri, S, Gaudieri, S., Audsley, J., Day, C, Caroline Day, Ayres, A, Day, C., Paul V. Desmond, Pfafferott, K., Gordon, A., Roberts, SK, Peter A. Revill, Alexander J. Thompson, Ayres, A., Desmond, CP, Sarah Chivers, Katja Pfafferott, Bowden, S., George K. Lau, Simon A. Mallal, Lewinb, SR, Lau, G.K., Roberts, S. K., Abha Chopra, Bowden, S, Mallal, S.A., Adam Gordon, Chivers, S   +56 more
core   +1 more source

VirusTAP: Viral Genome-Targeted Assembly Pipeline

Frontiers in Microbiology, 2016
Although next-generation sequencing (NGS) technology provides a comprehensive means with which to identify potential pathogens from clinical specimens, simple and user-friendly bioinformatics pipelines are expected to obtain the entire viral genome ...
Akifumi eYamashita, Tsuyoshi eSekizuka, Makoto eKuroda   +2 more
doaj   +1 more source