Results 11 to 20 of about 246,650 (312)
Structural Virology: The Key Determinants in Development of Antiviral Therapeutics [PDF]
VirusesStructural virology has emerged as the foundation for the development of effective antiviral therapeutics. It is pivotal in providing crucial insights into the three-dimensional frame of viruses and viral proteins at atomic-level or near-atomic-level ...
Tanuj Handa +6 more
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Unlocking the secrets of Feline calicivirus: advances in structural and nonstructural proteins and its role as a key model for other Caliciviruses [PDF]
Virology JournalFeline calicivirus (FCV) is a highly contagious pathogen responsible for respiratory infections, lingual ulceration, oral ulcers and systemic diseases in cats, posing a significant risk to feline family worldwide.
Sana Asif, Deng Yingkun, Chunchun Meng
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Targeting Viral Surface Proteins through Structure-Based Design [PDF]
Viruses, 2021 The emergence of novel viral infections of zoonotic origin and mutations of existing human pathogenic viruses represent a serious concern for public health. It warrants the establishment of better interventions and protective therapies to combat the virus and prevent its spread.
Yogesh B Narkhede +2 more
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Frontiers in Cellular and Infection Microbiology, 2021 Dengue is emerging as one of the most prevalent mosquito-borne viral diseases of humans. The 11kb RNA genome of the dengue virus encodes three structural proteins (envelope, pre-membrane, capsid) and seven non-structural proteins (NS1, NS2A, NS2B, NS3 ...
Priya Bhatnagar +6 more
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Visualization and analysis of hepatitis C virus structural proteins at lipid droplets by super-resolution microscopy. [PDF]
PLoS ONE, 2014 Cytosolic lipid droplets are central organelles in the Hepatitis C Virus (HCV) life cycle. The viral capsid protein core localizes to lipid droplets and initiates the production of viral particles at lipid droplet-associated ER membranes. Core is thought
Dennis Eggert +3 more
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MultiBac: from protein complex structures to synthetic viral nanosystems [PDF]
BMC Biology, 2017 The MultiBac baculovirus/insect cell expression vector system was conceived as a user-friendly, modular tool-kit for producing multiprotein complexes for structural biology applications. MultiBac has allowed the structure and function of many molecular machines to be elucidated, including previously inaccessible high-value drug targets.
Pelosse, Martin +5 more
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Genes of SARS-CoV-2 and emerging variants [PDF]
Microbiology Australia, 2021 The pandemic caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is distinctly different from outbreaks caused by other coronaviruses: SARS-CoV andMiddle East respiratory syndrome coronavirus (MERS-CoV).
Ian Macreadie, Sudip Dhakal
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An Overview of Spike Surface Glycoprotein in Severe Acute Respiratory Syndrome–Coronavirus
Frontiers in Molecular Biosciences, 2021 The novel coronavirus originated in December 2019 in Hubei, China. This contagious disease named as COVID-19 resulted in a massive expansion within 6 months by spreading to more than 213 countries.
Muthu Kumaradoss Kathiravan +5 more
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Вопросы вирусологии, 2023 Introduction. Kindia tick virus (KITV) is a novel segmented unclassified flavi-like virus of the Flaviviridae family. This virus is associated with ixodes ticks and is potentially pathogenic to humans.
A. A. Gladysheva +3 more
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Viruses, 2020 Protein-mediated membrane fusion is a highly regulated biological process essential for cellular and organismal functions and infection by enveloped viruses. During viral entry the membrane fusion reaction is catalyzed by specialized protein machinery on
Mark A. Benhaim, Kelly K. Lee
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