Results 31 to 40 of about 614,007 (276)

Viral Regulation of Cell Tropism in Human Cytomegalovirus [PDF]

Journal of Virology, 2016
ABSTRACT The viral glycoproteins that decorate enveloped viruses play crucial roles in cell entry and in large part dictate the spectrum of cell types that a virus can infect. The identification in human cytomegalovirus (HCMV) of a viral endoplasmic reticulum (ER)-resident glycoprotein that regulates the composition of alternative viral ...
Gang Li, Jeremy P. Kamil
openaire   +2 more sources

Association of X4 tropism with disease progression in antiretroviral-treated children and adolescents living with HIV/AIDS in São Paulo, Brazil

Brazilian Journal of Infectious Diseases, 2014
Management of children with HIV/AIDS is specially challenging. Age-related issues do not allow for direct transposition of adult observations to this population. CXCR4 tropism has been associated with disease progression in adults.
Flávia Jacqueline Almeida, Mayra Simioni Zaparoli, Denise Helena Moreira, Jaqueline de Souza Cavalcanti, Rosangela Rodrigues, Eitan Naaman Berezin, João Leandro de Paula Ferreira, Marco Aurélio Palazzi Sáfadi, Luis Fernando de Macedo Brígido   +8 more
doaj   +1 more source

High degree of concordance between flow cytometry and geno2pheno methods for HIV-1 tropism determination in proviral DNA

Brazilian Journal of Infectious Diseases, 2015
Use of CCR5 antagonists requires previous viral tropism determination. The available methods have high cost, are time-consuming, or require highly trained personnel, and sophisticated equipment.
Alex José Leite Torres, Luis Fernando de Macedo Brígido, Marcos Herculano Nunes Abrahão, Ana Luiza Dias Angelo, Gilcivaldo de Jesus Ferreira, Luana Portes Coelho, João Leandro Ferreira, Célia Regina Mayoral Pedroso Jorge, Eduardo Martins Netto, Carlos Brites   +9 more
doaj   +1 more source

Decreased HIV diversity after allogeneic stem cell transplantation of an HIV-1 infected patient : a case report [PDF]

, 2010
The human immunodeficiency virus type 1 (HIV-1) coreceptor use and viral evolution were analyzed in blood samples from an HIV-1 infected patient undergoing allogeneic stem cell transplantation (SCT).
Bravo Ignacio G, Wolf, Timo, Schnierle Barbara S, Schnierle, Barbara S, Thielen, A., Krause, B., Werner, A., Schnierle, Barbara, Christel Kamp, Bravo, I., Winskowsky, Gudrun, Albrecht Werner, Neumann, B., Thielen, Alexander, Werner Albrecht, Krause Birgit, Kamp Christel, Timo Wolf, Wolf, T., Thielen Alexander, Winskowsky, G., Kraus, Benjamin, Wolf Timo, Werner, Albrecht, Gudrun Winskowsky, Alexander Thielen, Neumann, Britta, Birgit Krause, Bravo, Ignacio G., Neumann Britta, Kraus, B., Kamp, Christel, Kamp, C., Ignacio G Bravo, Barbara S Schnierle, Krause, Birgit, Bravo, Ignacio G, Winskowsky Gudrun, Kraus Benjamin, Britta Neumann, Schnierle, B., Benjamin Kraus   +41 more
core   +1 more source

Avian Influenza Virus Tropism in Humans

, 2023
An influenza pandemic happens when a novel influenza A virus is able to infect and transmit efficiently to a new, distinct host species. Although the exact timing of pandemics is uncertain, it is known that both viral and host factors play a role in ...
Jasmine Elanie Khairat, Lina Amrani, Pouya Hassandarvish, Farah Ayuni Kamarulzaman, Saiful Anuar Karsani, Umarqayum AbuBakar   +5 more
core   +1 more source

Human T-Cell Leukemia Virus Type 1 Envelope Protein: Post-Entry Roles in Viral Pathogenesis

Viruses, 2022
Human T-cell leukemia virus type 1 (HTLV-1) is an oncogenic retrovirus that is the causative infectious agent of adult T-cell leukemia/lymphoma (ATL), an aggressive and fatal CD4+ T-cell malignancy, and HTLV-1-associated myelopathy/tropical spastic ...
Victoria Maksimova, Amanda R. Panfil
doaj   +1 more source

Avian Bornaviruses Escape Recognition by the Innate Immune System [PDF]

, 2010
Like other pathogens that readily persist in animal hosts, members of the Bornaviridae family have evolved effective mechanisms to evade the innate immune response.
Kothlow, Sonja, Ackermann, Andreas, Stäheli, Peter, Peter Staeheli, Staeheli, Peter, Kaspers, Bernd, Antje Reuter, Andreas Ackermann, Sonja Kothlow, Rinder, Monika, Monika Rinder, Reuter, Antje, Bernd Kaspers, Staeheli, Ackermann, Reuter, Kothlow, Kaspers, Rinder   +18 more
core   +1 more source

Entrapment of viral capsids in nuclear PML cages is an intrinsic antiviral host defense against varicella-zoster virus. [PDF]

, 2011
The herpesviruses, like most other DNA viruses, replicate in the host cell nucleus. Subnuclear domains known as promyelocytic leukemia protein nuclear bodies (PML-NBs), or ND10 bodies, have been implicated in restricting early herpesviral gene expression.
Baiker Armin, Sommer, Marvin, Nour Adel M., Sen Nandini, Wang, Li, Leigh Zerboni, Nandini Sen, Reichelt, Mike, Adel M. Nour, Mike Reichelt, Zerboni, Leigh, Marvin Sommer, Perrino, John, Reichelt Mike, Arvin Ann M., Arvin, Ann M., Ann M Arvin, Nour, Adel M., Baiker, Armin, John Perrino, Zerboni Leigh, Ann M. Arvin, Sommer Marvin, Adel M Nour, Perrino John, Li Wang, Armin Baiker, Sen, Nandini, Wang Li   +28 more
core   +2 more sources

The Viral Replication Complex Is Associated with the Virulence of Newcastle Disease Virus [PDF]

, 2010
Virulent strains of Newcastle disease virus ([NDV] also known as avian paramyxovirus type 1) can be discriminated from low-virulence strains by the presence of multiple basic amino acid residues at the proteolytic cleavage site of the fusion (F) protein.
Peeters, B.P.H., G. Koch, B. P. H. Peeters, Rottier, P.J.M., Dortmans, J.C.F.M., J. C. F. M. Dortmans, P. J. M. Rottier, Koch, G.   +7 more
core   +1 more source

Spatial transcriptomics for profiling the tropism of viral vectors in tissues

Nature Biotechnology, 2023
Abstract A barrier to advancing engineered adeno-associated viral vectors (AAVs) for precision access to cell subtypes is a lack of high-throughput, high-resolution assays to characterize in vivo transduction profiles. In this study, we developed an ultrasensitive, sequential fluorescence in situ hybridization (USeqFISH) method for ...
Min Jang, Gerard Coughlin, Cameron Jackson, Xinhong Chen, Miguel Chuapoco, Julia Vendemiatti, Alexander Wang, Viviana Gradinaru   +7 more
openaire   +3 more sources