Results 31 to 40 of about 370,832 (346)

Long-Read High-Throughput Sequencing (HTS) Revealed That the Sf-Rhabdovirus X+ Genome Contains a 3.7 kb Internal Duplication

open access: yesViruses, 2023
We previously reported a novel rhabdovirus produced from the Spodoptera frugiperda Sf9 cell line, designated as Sf-rhabdovirus X+ since it contained a unique accessory gene X.
Hailun Ma, Trent J. Bosma, Arifa S. Khan
doaj   +1 more source

Targeted-pig trial on safety and immunogenicity of serum-derived extracellular vesicles enriched fractions obtained from Porcine Respiratory and Reproductive virus infections [PDF]

open access: yes, 2018
The Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) is the etiological agent of one of the most important swine diseases with a significant economic burden worldwide.
Borrás, Francesc E.   +6 more
core   +4 more sources

The role of research in viral disease eradication and elimination programs: Lessons for malaria eradication [PDF]

open access: yes, 2011
By examining the role research has played in eradication or regional elimination initiatives for three viral diseases-smallpox, poliomyelitis, and measles-we derive nine cross-cutting lessons applicable to malaria eradication.
Breman, JG   +6 more
core   +1 more source

Vaccine-Associated Enhanced Viral Disease: Implications for Viral Vaccine Development [PDF]

open access: yesBioDrugs, 2021
Vaccine-associated enhanced disease (VAED) is a serious barrier to attaining successful virus vaccines in human and veterinary medicine. VAED occurs as two different immunopathologies, antibody-dependent enhancement (ADE) and vaccine-associated hypersensitivity (VAH).
openaire   +2 more sources

Antibody affinity and cross-variant neutralization of SARS-CoV-2 Omicron BA.1, BA.2 and BA.3 following third mRNA vaccination

open access: yesNature Communications, 2022
Here the authors show that a third SARS-CoV-2 vaccination significantly boosts neutralizing antibodies against Omicron subvariants and that hybrid immunity (infection and vaccination) results in broader neutralization activity and cross-reactive antibody
Lorenza Bellusci   +6 more
doaj   +1 more source

SARS-CoV-2 B.1.1.7 (alpha) and B.1.351 (beta) variants induce pathogenic patterns in K18-hACE2 transgenic mice distinct from early strains

open access: yesNature Communications, 2021
Mutant SARS-CoV-2 strains such as B.1.1.7 and B.1.351 have been termed variants of concerns (VoC) due to their enhanced virulence. Here the authors show, using K18-hACE2 transgenic mouse models, that these two VoCs are also more pathogenic in mice, and ...
Peter Radvak   +11 more
doaj   +1 more source

Using the nonhuman primate model of HCMV to guide vaccine development. [PDF]

open access: yes, 2014
The natural history of human cytomegalovirus (HCMV) is inextricably associated with mucosal surfaces. The vast preponderance of primary infections occur following mucosal exposure to infectious virions, and the high seroprevalence of HCMV throughout the ...
Barry, Peter A, Deere, Jesse D
core   +3 more sources

Coverage with Timely Administered Vaccination against Hepatitis B Virus and Its Influence on the Prevalence of HBV Infection in the Regions of Different Endemicity

open access: yesVaccines, 2021
Universal hepatitis B vaccination of newborns was implemented in Russia starting from 1998. From 1998 to 2019, the incidence of acute hepatitis B reduced from 43.8 to 0.57 cases per 100,000 population.
Karen K. Kyuregyan   +15 more
doaj   +1 more source

MODELLING OF HEPATITIS E IN MINI-PIGS

open access: yesЖурнал микробиологии, эпидемиологии и иммунобиологии, 2017
Aim. Experimental reproduction of HEV-infection in mini-pigs and comparative analysis of virological and immunological characteristics of experimental infection. Materials and methods.
S. A. Gulyaev   +9 more
doaj   +1 more source

The Immunological and Epidemiological Effectiveness of Pediatric Single-Dose Vaccination against Hepatitis A 9 to 11 Years after Its Implementation in the Tyva Republic, the Russian Federation

open access: yesVaccines
Since 2012, universal single-dose HAV vaccination in children aged 3 years and older has been implemented in the Tyva Republic, a region of the Russian Federation.
Maria A. Lopatukhina   +9 more
doaj   +1 more source

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