Results 81 to 90 of about 349,023 (332)

Protocol for a Scoping/Systematic Review: Scoping Review of Vaccination for the Prevention of Calf Scours in Cow-Calf Operations [PDF]

open access: yes, 2020
Background: The use of antimicrobials in the livestock industry has been a topic of increasing concern in the last  few years. Calf scours is one of the main causes of mortality among calves younger than 1 month and affects the development of the animal,
Breitenbuecher, Jefferson GC   +4 more
core  

Viral Vaccines of the Future

open access: yesPediatric Clinics of North America, 1990
Varicella vaccine seems close to licensure in the United States. It is likely to be recommended for routine use in healthy children, either administered singly or as a combination of MMR. Healthy children who have been immunized develop excellent antibody and cell-mediated responses to VZV in the absence of significant adverse effects, and they are ...
openaire   +3 more sources

Strategies to Design and Optimize Artificial Antigen‐Presenting Cells for T Cell Expansion in Cancer Immunotherapy

open access: yesAdvanced Functional Materials, EarlyView.
This review highlights recent advances in engineering artificial antigen‐presenting cells (aAPCs) as alternatives to dendritic cells for T cell expansion. Key design principles inspired by the immunological synapse are discussed, with emphasis on strategies for polyclonal and antigen‐specific T cell expansion.
Nguyen Thi Nguyen, Yu Seok Youn
wiley   +1 more source

Virus-like Particles (VLPs) as Important Tools for Flavivirus Vaccine Development

open access: yesBiologics, 2022
Flaviviruses, such as dengue, zika, yellow fever, West Nile, and Japanese encephalitis virus, are RNA viruses belonging to the Flaviviridae family (genus Flavivirus).
Leda R. Castilho   +3 more
doaj   +1 more source

A dose-dependent plasma signature of the safety and immunogenicity of the rVSV-Ebola vaccine in Europe and Africa. [PDF]

open access: yes, 2017
The 2014-2015 Ebola epidemic affected several African countries, claiming more than 11,000 lives and leaving thousands with ongoing sequelae. Safe and effective vaccines could prevent or limit future outbreaks.
Agnandji, ST   +17 more
core   +2 more sources

Viral vectors for vaccine applications

open access: yesClinical and Experimental Vaccine Research, 2013
Traditional approach of inactivated or live-attenuated vaccine immunization has resulted in impressive success in the reduction and control of infectious disease outbreaks. However, many pathogens remain less amenable to deal with the traditional vaccine strategies, and more appropriate vaccine strategy is in need.
Jun Chang, Young Joo Choi
openaire   +3 more sources

Synthetic Strategy for mRNA Encapsulation and Gene Delivery with Nanoscale Metal‐Organic Frameworks

open access: yesAdvanced Functional Materials, EarlyView.
This research utilizes the ZIF‐8 for the encapsulation and intracellular delivery of nucleic acids, specifically mRNA, for applications in gene delivery. Integrating PEI addresses the issue of mRNA leakage from ZIF‐8, resulting in the delivery and expression of green fluorescent protein (GFP) in vitro and firefly luciferase in vivo.
Harrison Douglas Lawson   +12 more
wiley   +1 more source

A Multicenter Study To Evaluate the Performance of High-Throughput Sequencing for Virus Detection

open access: yesmSphere, 2017
The capability of high-throughput sequencing (HTS) for detection of known and unknown viruses makes it a powerful tool for broad microbial investigations, such as evaluation of novel cell substrates that may be used for the development of new biological ...
Arifa S. Khan   +7 more
doaj   +1 more source

The Influence of Adjuvant Type on the Immunogenicity of RBD/N Cocktail Antigens as a Vaccine Candidate against SARS-CoV-2 Virus

open access: yesMicrobiology Spectrum, 2023
The emerging virus SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2 virus), agent of COVID-19, appeared in December 2019 in Wuhan, China, and became a serious threat to global health and public safety. Many COVID-19 vaccines have been approved
Gabriela Brzuska   +6 more
doaj   +1 more source

Viral Vaccine Strategies

open access: yesJournal of Biotechnology Research Center, 2022
Background: Lately, many viruses emerged or re-emerged from the obscurity and became considerable threats to the global health, raising alarms concerning their constant epidemic transmissions. A very important public health concern of those viruses is the continuous circulation amongst the population of the immunologically naive, susceptible hosts ...
openaire   +2 more sources

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