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The architecture of the SARS-CoV-2 RNA genome inside virion
Nature Communications, 2021 SARS-CoV-2 carries the largest single-stranded RNA genome and is the causal pathogen of the ongoing COVID-19 pandemic. How the SARS-CoV-2 RNA genome is folded in the virion remains unknown.
Changchang Cao, Zhaokui Cai, Minnan Yang
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SARS-CoV-2 spike-protein D614G mutation increases virion spike density and infectivity
Nature Communications, 2020 SARS-CoV-2 variants with spike (S)-protein D614G mutations now predominate globally. We therefore compare the properties of the mutated S protein (SG614) with the original (SD614).
Lizhou Zhang, Cody B Jackson, Huihui Mou
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Zika Virus NS2A-Mediated Virion Assembly
mBio, 2019 The flavivirus virion consists of an envelope outer layer, formed by envelope (E) and membrane (M) proteins on a lipid bilayer, and an internal core, formed by capsid (C) protein and genomic RNA. The molecular mechanism of flavivirus assembly is not well
Xianwen Zhang +7 more
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Influenza A Virus Cell Entry, Replication, Virion Assembly and Movement
Frontiers in Immunology, 2018 Influenza viruses replicate within the nucleus of the host cell. This uncommon RNA virus trait provides influenza with the advantage of access to the nuclear machinery during replication.
Dan Dou, Henrik Östbye, Robert daniels
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Applied Microbiology and Biotechnology, 2017 Bacteriophages are bacterial viruses that infect the host after successful receptor recognition and adsorption to the cell surface. The irreversible adherence followed by genome material ejection into host cell cytoplasm must be preceded by the passage ...
Agnieszka Latka +2 more
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Identifying Phage Virion Proteins by Using Two-Step Feature Selection Methods
Molecules, 2018 Accurate identification of phage virion protein is not only a key step for understanding the function of the phage virion protein but also helpful for further understanding the lysis mechanism of the bacterial cell. Since traditional experimental methods
Jiu-Xin Tan +4 more
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Nature Microbiology, 2019 Flaviviruses, including dengue virus and Zika virus, extensively remodel the cellular endomembrane network to generate replication organelles that promote viral genome replication and virus production.
Christopher John Neufeldt +2 more
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RF_phage virion: Classification of phage virion proteins with a random forest model
Frontiers in Genetics, 2023 Introduction: Phages play essential roles in biological procession, and the virion proteins encoded by the phage genome constitute critical elements of the assembled phage particle.Methods: This study uses machine learning methods to classify phage ...
Yanqin Zhang, Zhiyuan Li
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Conserved and host-specific features of influenza virion architecture
Nature Communications, 2014 Viruses use virions to spread between hosts, and virion composition is therefore the primary determinant of viral transmissibility and immunogenicity. However, the virions of many viruses are complex and pleomorphic, making them difficult to analyse in ...
Edward C Hutchinson +2 more
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Virion assembly and release. [PDF]
Current Topics in Microbiology and Immunology, 2013 Hepatitis C Virus (HCV) particles exhibit several unusual properties that are not found in other enveloped RNA viruses, most notably their low buoyant density and interaction with serum lipoproteins. With the advent of systems to grow HCV in cell culture, the molecular basis of HCV particle assembly and release can now be addressed.
B. Lindenbach
semanticscholar +3 more sources